Gram-negative bacteria

a group of bacteria that do not retain the crystal violet stain used in the Gram staining method, characterized by their cell wall structure

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Synthesis QSAR (quantitative structure-activity relationship) Inhibitors Heterocyclic compounds Molecular docking IC50 Pharmacophore Cytotoxicity binding affinity Precursor antimicrobial agents Minimum inhibitory concentration (MIC) Intermediate X-ray crystallography Analogues Chemical modification Tetrahydropyran Enzyme inhibition In vitro Testing In Vivo Testing Biological Evaluation Lead Optimization Zone of Inhibition Virtual Screening Structure Broad-Spectrum Activity Resistance Structure-Activity Relationship (SAR) Antiviral Activity Enzyme Kinetics Drug Resistance Drug Repurposing Functional Groups MIC Determination Bioavailability Mycobacterium tuberculosis In Silico Studies Antitubercular Agents Metabolic Stability Antifungal Activity Scaffold Hopping Toxicity Profile Bioisosteres Experimental terms SAR (Structure-Activity Relationship) Sisomicin Quinazolinones Docking simulation Gram-positive bacteria MIC assay

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