Vinyl epoxides can generate radicals upon activation. You'll need to model how these radicals are formed and their reactivity with the DNA.
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2-<2-(tert-butyldiphenylsiloxy)ethoxy>ethyl 2,3-epoxypent-4-enyl ether
2-Pentenoic acid, 5-phenyl-, (Z)-
NaH
(1S,6R)-N-[N-(S)-(p-toluenesulfonyl)-p-toluenesulfonimidoyl]-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-enamine
3,3-dimethyl-1-phenylsulphonyl butane
2-HEXANONE OXIME
trans-2-cyclohexyl-5-methylidene-6-methyl-1,3-dioxan-4-one
1,3,4,6-tetra-O-acetyl-2-O-(diphenylphosphoryl)-α-D-glucopyranose