RP-HPLC

reverse-phase high-performance liquid chromatography, a technique used to separate and purify compounds based on their polarity.

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Design, synthesis, and structure-activity relationships of novel insulin receptor tyrosine kinase activators
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Chemical shifts NMR Column chromatography Sodium bicarbonate Melting point Coupling constants brine MgSO4 reflux Optimization CDCl3 Ethyl acetate Rotary evaporation Singlet, doublet, triplet, etc. DMSO CD3OD TMS C18 stationary phase CH3CN H2O TFA NH4OAc High-Throughput Screening In Vivo Testing Preclinical and Clinical Development Regulatory Approval Post-Market Surveillance Structure Elucidation Target Selection and Validation Lead Generation Medicinal Chemistry and Chemical Synthesis Structure-Activity Relationships (SAR) Study Pharmacokinetics and Toxicology Assessment

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