Systematically vary the structure of the lead compound to understand how specific chemical modifications affect IRTK activation. Evaluate the activity of these derivatives in in vitro kinase assays and cell-based assays.
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4-methylphenyl 3-[({7-[({7-[({3-[(4-methylphenyl)oxysulfonyl]phenyl}amino)sulfonyl]-2-naphthyl}amino)carbonylamino]-2-naphthyl}sulfonyl)amino]benzenesulfonate
5-Amino-2-chlorobenzoic acid
Pyridine
