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CAS No.: | 100-69-6 |
---|---|
Name: | 2-Vinylpyridine |
Article Data: | 103 |
Molecular Structure: | |
Formula: | C7H7N |
Molecular Weight: | 105.139 |
Synonyms: | Pyridine,2-vinyl- (8CI);2-Ethenylpyridine;2-Pyridylethylene;NSC18255;a-Vinylpyridine; |
EINECS: | 202-879-8 |
Density: | 0.968 g/cm3 |
Melting Point: | -50 °C |
Boiling Point: | 160.3 °C at 760 mmHg |
Flash Point: | 46.7 °C |
Solubility: | 2.5 g/100 mL (20 °C) in water |
Appearance: | dark brown liquid with an unpleasant odour |
Hazard Symbols: | T,C,F |
Risk Codes: | 10-20-25-34-42/43 |
Safety: | 16-23-26-36/37/39-45-28A |
Transport Information: | UN 3073 6.1/PG 2 |
PSA: | 12.89000 |
LogP: | 1.72460 |
Conditions | Yield |
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With hydrogen In toluene at 20℃; under 22801.5 Torr; for 12h; Autoclave; chemoselective reaction; | 99% |
With hydrogen In toluene at 110℃; under 760.051 Torr; for 24h; Schlenk technique; | 87% |
With ammonium formate In N,N-dimethyl-formamide at 80℃; Green chemistry; | 76% |
diethyl-(2-pyridin-2-yl-ethyl)-amine
2-vinylpyridine
Conditions | Yield |
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92.3% |
Conditions | Yield |
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With (IMes)CuCl; triphenylphosphine; isopropyl alcohol In 1,4-dioxane; diethyl ether at 60℃; for 16h; | 86% |
Conditions | Yield |
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With cesium fluoride In ethanol; water at 50℃; for 5h; Stille coupling; Inert atmosphere; | 82% |
2-(pyridin-2-yl)ethyl methanesulfonate
2-vinylpyridine
Conditions | Yield |
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With N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide In water at 40℃; for 2h; | 80% |
With sodium carbonate |
Conditions | Yield |
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With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran for 6h; Ambient temperature; | 73% |
Conditions | Yield |
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With acetic acid for 12h; Heating; | 70% |
With sodium tetrafluoroborate; acetic acid In N,N-dimethyl acetamide at 150℃; for 24h; Reagent/catalyst; | 64% |
With tris(triphenylphosphine)ruthenium(II) chloride; 1,3-bis-(diphenylphosphino)propane; sodium t-butanolate In toluene at 111℃; for 24h; Inert atmosphere; | 41% |
Conditions | Yield |
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borininato-cobalt-COD catalyst at 120℃; under 38253.1 Torr; for 2h; | 62% |
With (η-1,5-cyclooctadien(<1-6-η-(1-phenylborinato)>cobalt at 120℃; under 38253.1 Torr; for 2.08333h; | 61.5% |
Conditions | Yield |
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With sodium tetrafluoroborate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; copper diacetate; acetic acid In N,N-dimethyl acetamide at 150℃; for 24h; Time; | A 26% B 53% |
Conditions | Yield |
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at 800℃; under 0.1 Torr; | 45% |
The 2-Vinylpyridine, with the CAS registry number 100-69-6, is also known as 2VP. It belongs to the product categories of Pyridines Derivates; Monomers; Polymer Science; Vinyl Halides, Amines, Amides, and Other Vinyl Monomers; C7 and C8; Heterocyclic Building Blocks; Pyridines. Its EINECS registry number is 202-879-8. This chemical's molecular formula is C7H7N and molecular weight is 105.13718. Its IUPAC name is called 2-ethenylpyridine. The product can be used to prepare modification latex of vinyl pyridine with butadiene or styrene copolymerization. In addition, it also can be used for binder. 2-Vinylpyridine is a useful intermediate for the production of polymers.
Physical properties of 2-Vinylpyridine: (1)ACD/LogP: 1.34; (2)ACD/LogD (pH 5.5): 1.23; (3)ACD/LogD (pH 7.4): 1.34; (4)ACD/BCF (pH 5.5): 4.78; (5)ACD/BCF (pH 7.4): 6.1; (6)ACD/KOC (pH 5.5): 99.31; (7)ACD/KOC (pH 7.4): 126.9; (8)#H bond acceptors: 1; (9)#Freely Rotating Bonds: 1; (10)Index of Refraction: 1.562; (11)Molar Refractivity: 35.26 cm3; (12)Molar Volume: 108.6 cm3; (13)Surface Tension: 36.1 dyne/cm; (14)Density: 0.968 g/cm3; (15)Flash Point: 46.7 °C; (16)Enthalpy of Vaporization: 38.05 kJ/mol; (17)Boiling Point: 160.3 °C at 760 mmHg; (18)Vapour Pressure: 3.13 mmHg at 25°C.
Preparation of 2-Vinylpyridine: this chemical can be obtained from 2-hydroxyethyl pyridine by dehydration.
Uses of 2-Vinylpyridine: it can be used to produce 4-chlorophenyl 2-(2-pyridyl)ethyl sulfide at temperature of 60 °C. This reaction is a kind of Alkylation. It will need 2.5 hours. The yield is about 93%.
When you are using this chemical, please be cautious about it as the following:
This chemical may destroy living tissue on contact and may cause burns. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. Whenever you will contact it, please wear suitable protective clothing, gloves and eye/face protection.
You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C=CC1=CC=CC=N1
(2)InChI: InChI=1S/C7H7N/c1-2-7-5-3-4-6-8-7/h2-6H,1H2
(3)InChIKey: KGIGUEBEKRSTEW-UHFFFAOYSA-N
The toxicity data is as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LDLo | skin | 500mg/kg (500mg/kg) | "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 845, 1986. | |
mammal (species unspecified) | LD50 | oral | 415mg/kg (415mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(4), Pg. 86, 1974. | |
mouse | LC50 | inhalation | 460mg/m3 (460mg/m3) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 10(3), Pg. 9, 1966. | |
mouse | LD50 | oral | 420mg/kg (420mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 10(3), Pg. 9, 1966. | |
rat | LC50 | inhalation | 610mg/m3 (610mg/m3) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 57(9-10), Pg. 64, 1992. | |
rat | LD50 | oral | 100mg/kg (100mg/kg) | "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 845, 1986. |