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119413-54-6

Basic Information
CAS No.: 119413-54-6
Name: 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, hydrochloride (1:1), (4S)-
Article Data: 10
Cas Database
Molecular Structure:
Molecular Structure of 119413-54-6 (1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, hydrochloride (1:1), (4S)-)
Formula: C23H23N3O5.HCl
Molecular Weight: 457.914
Synonyms: Topotecan HCl;Hycamtin;NSC 609669;Nogitecan hydrochloride;SKF 104864A;SKFS 104864A;
EINECS: 601-607-9
Density: 1.49 g/cm3
Melting Point: 213-218 °C
Boiling Point: 782.9 °C at 760 mmHg
Flash Point: 427.3 °C
Solubility: N/A
Appearance: White Crystalline Solid
Hazard Symbols: ToxicT
Risk Codes: 25-36/37/38-46
Safety: 26-36/37/39-45
Transport Information: N/A
PSA: 104.89000
LogP: 2.64880
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    Specification:USP/EP Month production ablity:50kg/Month Low price& High quality Manufacturer Name Topotecan hydrochloride Synonyms (S)-10-[(Dimethylamino)me

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  • Topotecan Hydrochloride 119413-54-6

  • Casno:

    119413-54-6

    Topotecan Hydrochloride 119413-54-6

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

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  • Topotecanhydrochloride

  • Casno:

    119413-54-6

    Topotecanhydrochloride

    Min.Order: 1 Gram

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  • China Manufacturer High Purity Topotecan hydrochloride CAS NO.119413-54-6

  • Casno:

    119413-54-6

    China Manufacturer High Purity Topotecan hydrochloride CAS NO.119413-54-6

    Min.Order: 25 Metric Ton

    FOB Price:  USD $ 10.0-15.0/Metric Ton

    About us: Hebei wego import and export Co. LTD is located in Hebei province of China, limited is specialized in the production of high complex new type intermediates and chemical custom synthesis, scale-up production and rare chemicals trade. produ

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  • Topotecan hydrochloride

  • Casno:

    119413-54-6

    Topotecan hydrochloride

    Min.Order: 0

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  • High Quality API Topotecan hydrochloride Powder Anti-cancer raw materials

  • Casno:

    119413-54-6

    High Quality API Topotecan hydrochloride Powder Anti-cancer raw materials

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Chemistry

The Molecular formula of  Topotecan HCl (119413-54-6): C23H24ClN3O5
The Molecular Weight of  Topotecan HCl (119413-54-6): 457.91
Molecular Structure : 
Melting point:  213-218 °C 
Index of Refraction: 1.733
Surface Tension: 82.8 dyne/cm
Density: 1.49 g/cm3
Flash Point: 427.3 °C
Enthalpy of Vaporization: 119.49 kJ/mol
Boiling Point: 782.9 °C at 760 mmHg
Vapour Pressure: 8.13E-26 mmHg at 25 °C 
Appearance of Topotecan HCl (119413-54-6): White Crystalline Solid

 

Uses

 Topotecan HCl (119413-54-6) is naturally occurring amino acid.It is the precursor of tetrapyrroles in the biosynthesis of chlorophyll and heme.And it is antineoplastic (photosensitizer),especially a DNA topoisomerase I inhibitor,just like semisynthetic analog of Camptothecin.

Safety Profile

The Hazard Codes of  Topotecan HCl (119413-54-6) :  T
The Risk Statements information of  Topotecan HCl (119413-54-6): 25-36/37/38-46
25:  Toxic if swallowed 
46:  May cause heritable genetic damage
36/37/38:  Irritating to eyes, respiratory system and skin
The Safety Statements information of  Topotecan HCl (119413-54-6): 26-36/37/39-45
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice    
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) 
36/37/39:  Wear suitable protective clothing, gloves and eye/face protection 

Specification

 Topotecan HCl (119413-54-6),also called topotecan monohydrochloride;topetecan hydrochloride;5-piperazin-1-yl-benzofuran-2-carboxylic acid ethyl ester,is white crystalline solid.