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151767-02-1

Basic Information
CAS No.: 151767-02-1
Name: Montelukast sodium
Molecular Structure:
Molecular Structure of 151767-02-1 (Montelukast sodium)
Formula: C35H35ClNNaO3S
Molecular Weight: 608.17
Synonyms: Cyclopropaneacetic acid,1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2- quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy- 1-methylethyl)phenyl]propyl]thio]methyl]-,monosodium salt;Singulair (TN);Singulair;sodium 2-[1-[[(1R)-1-[3-[2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetate;MK 476;
EINECS: 604-813-7
Density:
Melting Point: 115 °C(dec.)
Boiling Point: 750.5 °C at 760 mmHg
Flash Point: 407.7 °C
Solubility:
Appearance: White to off-white crystalline powder
Hazard Symbols: Xi
Risk Codes: 63-41-62
Safety: 26
Transport Information:
PSA:
LogP:
Synthetic route
1310-73-2

sodium hydroxide

158966-92-8

montelukast

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
In methanol; toluene at 20℃; for 1h; Product distribution / selectivity;100%
In methanol; toluene at 2 - 20℃; for 0.75h; Product distribution / selectivity;100%
In methanol at 20℃; for 1h; Product distribution / selectivity;73%
In methanol at 25 - 35℃; for 0.166667h;
158966-92-8

montelukast

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
With sodium hydroxide In methanol; toluene at 20℃; for 1h;100%
With sodium hydroxide In methanol; water; toluene for 0.5h; Product distribution / selectivity; Alkaline aqueous solution;98%
With sodium hydroxide In methanol at -5 - 35℃; for 1h;98.7%
577953-88-9

1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid dicyclohexylamine salt

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
Stage #1: 1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid dicyclohexylamine salt With acetic acid In dichloromethane pH=4 - 4.5;
Stage #2: With pyrographite; sodium hydroxide In methanol; water for 1h;
99%
Stage #1: 1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid dicyclohexylamine salt With acetic acid In dichloromethane; water pH=4 - 4.5;
Stage #2: With pyrographite; sodium hydroxide In methanol; water for 1h;
99%
Stage #1: 1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid dicyclohexylamine salt With acetic acid In water; toluene at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: With sodium hydroxide In methanol at 20 - 25℃; for 2h; Inert atmosphere;
94%
880769-29-9

1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid α-methylbenzylamine salt

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
Stage #1: 1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid α-methylbenzylamine salt With acetic acid In dichloromethane pH=4 - 4.5;
Stage #2: With pyrographite; sodium hydroxide In methanol; water for 1h;
99%
Stage #1: 1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid α-methylbenzylamine salt With acetic acid In dichloromethane; water pH=4 - 4.5;
Stage #2: With pyrographite; sodium hydroxide In methanol; water for 1h;
99%
Stage #1: 1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid α-methylbenzylamine salt With acetic acid In dichloromethane; water at 25 - 35℃; for 0.75h;
Stage #2: With sodium hydroxide In ethanol; dichloromethane at 25 - 30℃; for 1h; Product distribution / selectivity;
75.6%
Stage #1: 1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid α-methylbenzylamine salt With acetic acid In dichloromethane; water at 25 - 35℃;
Stage #2: With sodium hydroxide In ethanol at 25 - 30℃; Product distribution / selectivity;
75.6%
1100021-03-1

1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid benzylamine salt

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
Stage #1: 1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid benzylamine salt With acetic acid In dichloromethane; water pH=4 - 4.5;
Stage #2: With pyrographite; sodium hydroxide In methanol; water for 1h;
99%
Stage #1: 1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid benzylamine salt With acetic acid In dichloromethane pH=4 - 4.5;
Stage #2: With pyrographite; sodium hydroxide In methanol; water for 1h;
1254938-23-2

1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid 4-chloro benzylamine salt

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
Stage #1: 1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid 4-chloro benzylamine salt With acetic acid In dichloromethane pH=4 - 4.5;
Stage #2: With pyrographite; sodium hydroxide In methanol; water for 1h;
99%
Stage #1: 1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid 4-chloro benzylamine salt With acetic acid In dichloromethane; water pH=4 - 4.5;
Stage #2: With pyrographite; sodium hydroxide In methanol; water for 1h;
99%

1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid 4-methoxy benzylamine salt

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
Stage #1: 1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid 4-methoxy benzylamine salt With acetic acid In dichloromethane pH=4 - 4.5;
Stage #2: With pyrographite; sodium hydroxide In methanol; water for 1h;
99%
Stage #1: 1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid 4-methoxy benzylamine salt With acetic acid In dichloromethane; water pH=4 - 4.5;
Stage #2: With pyrographite; sodium hydroxide In methanol; water for 1h;
99%
1310-73-2

sodium hydroxide

577953-88-9

1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid dicyclohexylamine salt

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
Stage #1: 1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid dicyclohexylamine salt With water; acetic acid In toluene at 20 - 25℃; for 0.166667h;
Stage #2: sodium hydroxide In ethanol; water; toluene at 20℃; for 0.333333h;
98%
1254938-26-5

1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid 4-bromo benzylamine salt

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
Stage #1: 1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid 4-bromo benzylamine salt With acetic acid In dichloromethane pH=4 - 4.5;
Stage #2: With pyrographite; sodium hydroxide In methanol; water for 1h;
98%
Stage #1: 1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid 4-bromo benzylamine salt With acetic acid In dichloromethane; water pH=4.5;
Stage #2: With pyrographite; sodium hydroxide In methanol; water for 1h;
98%

1-(((1-(R)-(3-(2-(7-chloro-2-quinolinyl)-ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropylacetate 2-amino-1-butanol

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
Stage #1: 1-(((1-(R)-(3-(2-(7-chloro-2-quinolinyl)-ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropylacetate 2-amino-1-butanol With acetic acid In dichloromethane; water for 0.25h;
Stage #2: With pyrographite; sodium sulfate; sodium hydroxide In methanol at 15 - 25℃; for 1h; Temperature;
97.2%
918972-53-9

montelukast isopropylamine salt

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
With sodium t-butanolate In toluene at 30 - 35℃; for 0.75h; Product distribution / selectivity; Inert atmosphere; Darkness;94%
With sodium t-butanolate In toluene at 35℃;78%
Stage #1: montelukast isopropylamine salt With hydrogenchloride In dichloromethane; water at 10 - 25℃; for 0.5h; pH=4 - 4.5;
Stage #2: With sodium hydroxide In ethanol; dichloromethane at 8 - 12℃; for 2h;
Stage #1: montelukast isopropylamine salt With hydrogenchloride In dichloromethane; water at 10 - 20℃; pH=4 - 4.5; Inert atmosphere;
Stage #2: With sodium hydroxide In ethanol; dichloromethane at 8 - 12℃; for 30h; Inert atmosphere;

1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acid R-(+)-α-methylbenzylamine salt

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
With sodium methylate; pyrographite In toluene at 25 - 30℃; for 1.5h;93%
880769-26-6

1-(((1-(R)-(3-(2-(E)-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl) thio)methyl)cyclopropaneacetic acid dipropylamine salt

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
Stage #1: 1-(((1-(R)-(3-(2-(E)-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl) thio)methyl)cyclopropaneacetic acid dipropylamine salt With acetic acid In water; isopropyl alcohol at 4 - 40℃; for 17h; Inert atmosphere;
Stage #2: With sodium hydroxide In methanol for 1h;
92%
Stage #1: 1-(((1-(R)-(3-(2-(E)-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl) thio)methyl)cyclopropaneacetic acid dipropylamine salt With acetic acid In dichloromethane; water at 25 - 30℃; for 0.75h;
Stage #2: With sodium hydroxide In ethanol; dichloromethane at 25 - 30℃; for 1h; Product distribution / selectivity;
67.8%
Stage #1: 1-(((1-(R)-(3-(2-(E)-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl) thio)methyl)cyclopropaneacetic acid dipropylamine salt With acetic acid In dichloromethane; water at 25 - 35℃;
Stage #2: With sodium hydroxide In ethanol at 25 - 30℃; Product distribution / selectivity;
67.8%
142522-28-9

cyclopentyl 3-{2-methoxy-4-[(o-tolylsulfonyl)carbamoyl]benzyl}-1-methyl-1H-indol-5-ylcarbamate

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
With sodium hydroxide In methanol at 20℃; for 0.5h; Inert atmosphere;92%
942303-96-0

montelukast N-methyl-morpholine salt

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
With sodium methylate In toluene at 25 - 30℃; for 0.5h;90%

montelukast hexamethylenediamine

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
Stage #1: montelukast hexamethylenediamine With tartaric acid In dichloromethane; water for 0.25 - 0.333333h;
Stage #2: With sodium hydroxide In methanol; dichloromethane for 0.0833333 - 0.166667h;
90%

(R,E)-2-(1-((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)-phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propylthio)-methyl)cyclopropyl)acetic acid L-(-)-ephedrine

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
Stage #1: (R,E)-2-(1-((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)-phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propylthio)-methyl)cyclopropyl)acetic acid L-(-)-ephedrine With acetic acid In dichloromethane; water pH=7; Inert atmosphere;
Stage #2: With sodium hydroxide In methanol for 1h; Activated carbon;
86.8%
1312993-47-7

Montelukast L-ephedrine salt

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
Stage #1: Montelukast L-ephedrine salt With acetic acid In dichloromethane; water at 15 - 20℃; pH=7; Inert atmosphere;
Stage #2: With sodium hydroxide In methanol at 32℃;
86.8%
1100021-00-8

montelukast n-propylamine salt

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
With sodium t-butanolate In toluene at 30℃;82%
851755-58-3

montelukast tert-butylamine salt

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
Stage #1: montelukast tert-butylamine salt With acetic acid In dichloromethane; water for 0.5h; Industry scale;
Stage #2: With sodium hydroxide In methanol for 0.333333h; Industry scale;
75.4%
With sodium methylate In methanol at 25 - 35℃; for 1h; Product distribution / selectivity;
Stage #1: montelukast tert-butylamine salt With acetic acid In dichloromethane; water at 25 - 35℃; for 0.25h;
Stage #2: With sodium hydroxide; pyrographite In methanol at 25 - 35℃; for 0.5h;
1187364-41-5

[R-(E)]-1-[[[1-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid homoveratrylamine salt

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
Stage #1: [R-(E)]-1-[[[1-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid homoveratrylamine salt With acetic acid In dichloromethane; water at 0 - 5℃;
Stage #2: With sodium hydroxide In methanol at 25 - 35℃; Product distribution / selectivity;
75%
1020313-99-8

C39H43ClN2O2S

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
With sodium hydroxide; water; ethylene glycol at 120 - 195℃; for 3 - 25h; Product distribution / selectivity;60%
1399184-58-7

(1-{1-(R)-(E)-{3-[2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-3-[2-(1-hydroxy-1-methyl-ethyl)-phenyl]-propylsulfanylmethyl}-cyclopropyl)-acetic acid diisobutylamine salt

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
With sodium tert-pentoxide In methyl cyclohexane; toluene at 20 - 45℃; for 1.5h;56%
With sodium tert-pentoxide In toluene at 40 - 45℃; for 0.5h; Product distribution / selectivity; Inert atmosphere;56%
1008509-41-8

1-(((1(R)-(3-(2-(7-chloro-2-quinolinyl)ethenyl)-phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)-cyclopropaneacetic acid trans-4-aminocyclohexanol salt

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
Stage #1: 1-(((1(R)-(3-(2-(7-chloro-2-quinolinyl)ethenyl)-phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)-cyclopropaneacetic acid trans-4-aminocyclohexanol salt With tartaric acid In water for 1h;
Stage #2: With sodium hydroxide In methanol for 1h; Product distribution / selectivity;
945934-73-6

1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acid cyclohexylamine salt

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
Stage #1: 1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acid cyclohexylamine salt With tartaric acid In water for 1h;
Stage #2: With sodium hydroxide In methanol for 1h; Product distribution / selectivity;

1-[[[(1R)-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl] cyclopropane acetic acid magnesium salt

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
Stage #1: 1-[[[(1R)-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl] cyclopropane acetic acid magnesium salt With acetic acid In water at 25 - 30℃; for 0.5h;
Stage #2: With sodium hydroxide In ethanol; water at 25 - 30℃; for 0.5h;
855473-51-7

1-(((1(R)-(3-(2(E)-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid methyl ester

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
With sodium hydroxide In tetrahydrofuran; methanol; water at 24 - 27℃; for 20h; Product distribution / selectivity; Alkaline aqueous solution;
With sodium hydroxide In tetrahydrofuran; methanol at 20 - 25℃; for 50h;
With sodium hydroxide In tetrahydrofuran; ISOPROPYLAMIDE at 40℃; for 4h;
1310-73-2

sodium hydroxide

851755-58-3

montelukast tert-butylamine salt

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
In methanol at 5 - 10℃; for 0.5h; Product distribution / selectivity;
1310-73-2

sodium hydroxide

1028683-07-9

n-butylamine salt of montelukast

151767-02-1

Montelukast sodium

Conditions
ConditionsYield
In methanol at 5 - 10℃; for 0.5h; Product distribution / selectivity;
151767-02-1

Montelukast sodium

158966-92-8

montelukast

Conditions
ConditionsYield
With hydrogenchloride In water at 20 - 25℃; for 1h;97%
With hydrogenchloride In water at 20℃; for 1h; pH=6;97.9%
With hydrogenchloride; citric buffer In water; acetone at 20 - 25℃; for 2h;76%
143418-49-9

3,4,5-trifluorophenylboronic acid

151767-02-1

Montelukast sodium

C41H38F3NO3S

Conditions
ConditionsYield
With O4P(3-)*3K(1+)*5H2O; tris(1-adamantyl)phosphine; C28H26N2O8Pd2S2 In tetrahydrofuran at 100℃; for 5h; Suzuki-Miyaura Coupling; Inert atmosphere; Schlenk technique;89%
143418-49-9

3,4,5-trifluorophenylboronic acid

151767-02-1

Montelukast sodium

C41H38F3NO3S

Conditions
ConditionsYield
With O4P(3-)*3K(1+)*5H2O; tris(1-adamantyl)phosphine; {2-[((acetyl-κO)amino)phenyl-κC](tri-1-adamantylphosphine)palladium}(p-toluenesulfonate) In tetrahydrofuran at 100℃; for 5h; Suzuki-Miyaura Coupling; Inert atmosphere;89%
77-78-1

dimethyl sulfate

151767-02-1

Montelukast sodium

855473-51-7

1-(((1(R)-(3-(2(E)-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid methyl ester

Conditions
ConditionsYield
With sodium hydroxide In 1,4-dioxane Reflux;54%
151767-02-1

Montelukast sodium

[R,E]-1-[[[1-[3-[2-(7-chloro-2-quinolinyl) ethenyl]-phenyl]-3-[2-(-hydroxy-1-methylethyl) phenyl]propyl]-sulfinyl] methyl] cyclopropaneacetic acid

Conditions
ConditionsYield
With 3-chloro-benzenecarboperoxoic acid; trifluoroacetic acid In dichloromethane at -22℃; for 2h; Yield given;
Stage #1: Montelukast sodium With dihydrogen peroxide In methanol; water for 3h;
Stage #2: With acetic acid
With dihydrogen peroxide In methanol; water for 3h;
Downstream Products
158966-92-8
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  • Montelukast sodium CAS No. 151767-02-1

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    151767-02-1

    Montelukast sodium CAS No. 151767-02-1

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    Montelukast Sodium Tablets

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  • Casno:

    151767-02-1

    Montelukast sodium

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

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    Located in Zhengdong New District,?Zhengzhou of Henan province, Henan Allgreen Chemical Co.,Ltd is a comprehensive high-tech modern enterprises integrating professional R&D, pro

  •  Henan Allgreen Chemical Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-0371-87507775

    Address:No 260 Dongming Road,Jinshui District

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  • 151767-02-1  Montelukast sodium

  • Casno:

    151767-02-1

    151767-02-1 Montelukast sodium

    Min.Order: 1 Gram

    FOB Price:  USD $ 40.0-50.0/Gram

    1.good quality 1) good quality is the basic of our goal; 2) we can offer samples to be tested; 3) 98% of our products have exported to uk, usa, germany, spain, australia, middle east and many other countries. 4) Good feedback of quality from our cu

    Mulei (Wuhan) New Material Technology Co. Ltd is a scientific and technological company integrating product research and development, manufacture and trading of chemical intermedia

  •  WUHAN MULEI NEW MATERIAL CO., LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+8619831967063

    Address:Office1201#, Block C, Hanjie Headquarters International Plaza, Zhongbei Rd, Wuchang District, Wuhan

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  • Bulk Powder Montelukast sodium

  • Casno:

    151767-02-1

    MSDS/COA Download

    Bulk Powder Montelukast sodium

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    FOB Price:  USD $ 1.0-1.0/Kilogram

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    Shaanxi greenyo biotech co., ltd is one specialized company which engaged in the naturalplant extracts, pharmaceutical intermediates, chemical raw materials research and developmen

  •  Shaanxi Greenyo Biotech Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:86-29-81772657

    Address:Gaoxin 4th road, High-tech zone,

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  • Montelukast Sodium

  • Casno:

    151767-02-1

    Montelukast Sodium

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    Chemwill Asia co.,Ltd is one of the leading manufacturer in CHINA.Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Active pharmaceutical ingredients(APIs), Veterinary, Indole derivatives, Aro

    Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Fine chemicals, Active pharmaceutical ingredients(APIs), Veterinary, In

  •  Chemwill Asia Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:021-51086038

    Address:High-Tech Industrial park,Chemical Economical Development Zone,Xuzhou, Jiangsu-Province, P.R.China

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  • Montelukast sodium

  • Casno:

    151767-02-1

    Montelukast sodium

    Min.Order: 1 Metric Ton

    FOB Price:  USD $ 1.0-1.0/Metric Ton

    Production Name: Montelukast Sodium CAS NO:151767-02-1 EINECS No.:N//A Molecular Formula:C35H35ClNNaO3S MW:608.17 Category:API Appearance:White Powder Appearance:White powder Storage:Store in cool and dry place, away from

    Welcome to Henan Sinotech! Sinotech Corporation has exceptional sourcing ability for chemicals used in Organic Fine Chemicals and APIs; Inorganic chemicals; Flame Retardants;OLED

  •  Henan Sinotech Import&Export Corporation

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:86-371-86181678

    Address:No. 260, Dongming Road,Jinshui District

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  • TIANFUCHEM-- 151767-02-1--High purity Montelukast sodium in stock

  • Casno:

    151767-02-1

    TIANFUCHEM-- 151767-02-1--High purity Montelukast sodium in stock

    Min.Order: 1 Metric Ton

    FOB Price:  USD $ 2000.0-2000.0/Metric Ton

    TIANFUCHEM-- 151767-02-1--High purity Montelukast sodium in stock Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable busin

    Our company engages in Electronic chemicals such as OLED,Photoresist chemical,Electrolyte additive and Intermediate Pharmaceutical production; development of noble metal catalysts,

  •  Henan Tianfu Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-371-55170693/55170694

    Address:Zhengzhou International Trade New Territory,Jinshui District,Zhengzhou ,China

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  • Anti-inflammatory drugs/Montelukast sodium

  • Casno:

    151767-02-1

    Anti-inflammatory drugs/Montelukast sodium

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    Montelukast Quick details Chemical Name: Montelukast CAS No.:151767-02-1 Appearence: powder Montelukast COA Item Standard Result

    Shaanxi Mingqi Chemical Co., Ltd is committed to the development of import and export trade in the production, operation and plant extracts of pharmaceutical raw materials and inte

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     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:18092428356

    Address:Weiyang District

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  • Montelukast sodium CAS 151767-02-1  Pharmaceutical Raw materials for antiasthmatic

  • Casno:

    151767-02-1

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    Min.Order: 10 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Our Adwantage: 1.We have stock so we can delivery quickly at the very day when receive the payment. 2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order. 3.High quality gua

    Hubei Xinrunde Chemical Co., Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredient(s)

  •  Hubei XinRunde Chemical Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:+8618874586545

    Address:No.43, Xinandu Industrial Park, East and West Lake District, Wuhan, Hubei, China

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  • Pharmaceutical Grade CAS 151767-02-1 with competitive price

  • Casno:

    151767-02-1

    Pharmaceutical Grade CAS 151767-02-1 with competitive price

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 139.0-210.0/Kilogram

    WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

    Zhuo Zhou Wen Xi Import and Export Co., Ltd. is a company mainly engaged in the export of pharmaceutical raw materials. Its parent company is (Wen Xi Pharma), including three subs

  •  Zhuozhou Wenxi import and Export Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-13111626072

    Address:Room 1710, Baoxin International Phase I, 19 Guanyun East Road, Zhuozhou, Hebei

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  • Casno:

    151767-02-1

    MSDS/COA Download

    BLOOM TECH Advanced API/Technology support Montelukast sodium CAS 151767-02-1

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Inquiry guide 1.Please send the quantity(Weight) to us, we will arrange our sales to provide the one-for-one service for you. 2.Then we will provide the professional quotation list for you, it will be including all the factors in who

    WHO WE ARE 1.We Focus on the technology of Organic Synthesis since 2008. 2.API/Pharmaceutical intermediate/Fine chemical/New material/Extraction etc. 3.Chemical reagent: Over 300,0

  •  Shaanxi BLOOM TECH Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-29-86470566

    Address:Block A of Central Mansion, No.113 of Weiyang Rd, ETDZ, Xi'an, Shaanxi 710016, China

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  • Casno:

    151767-02-1

    Montelukast sodium/ LIDE PHARMA- Factory supply / Best price

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&

    LIDE PHARMACEUTICALS LIMITED is one of the fastest growing pharmaceutical company in China. We have developed strategic partnership with our manufacturing associates having state o

  •  LIDE PHARMACEUTICALS LIMITED

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-25-58409506

    Address:11F, Building A1, No.288 North Zhongshan Road, Gulou District, Nanjing,210003, P.R.China.

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  • Montelukast sodium CAS 151767-02-1

  • Casno:

    151767-02-1

    MSDS/COA Download

    Montelukast sodium CAS 151767-02-1

    Min.Order: 10 Gram

    FOB Price:  USD $ 1.0-50.0/Gram

    WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Ita

    HUBEI AOKS BIO-TECH CO.,LTD is located in Hubei province of China.We specialized in Active pharmaceutical ingredient,pharmaceutical intermediates,veterinary drug intermediates and

  •  HUBEI AOKS BIO-TECH CO.,LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-27-52345788

    Address:28F,China Construction Third Bureau,Wuhan,Hubei Province, China

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  • High quality Montelukast sodium CAS 151767-02-1 with favorable price

  • Casno:

    151767-02-1

    High quality Montelukast sodium CAS 151767-02-1 with favorable price

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 500.0-500.0/Kilogram

    1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:White Powder Storage:-20°C Freezer, Under Inert Atmosphere Pa

    Wuhan Fortuna Chemical Co., Ltd, located in the predominant Wu Han City where is a traffic hinge of China, is a big integrative chemical enterprise being engaged in producing and

  •  Wuhan Fortuna Chemical Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-27-59207850

    Address:A2705,Dong Yi Shi Qu,129# XinHua Road,WuHan,China

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  • Montelukast sodium 151767-02-1

  • Casno:

    151767-02-1

    Montelukast sodium 151767-02-1

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

    Shanghai Upbio Tech Co.,Ltd (Former Onchem (China)Co.,Ltd) is a comprehensive manufacturer and an international distribution of chemicals throughout the world, The predecessor of

  •  Shanghai Upbio Tech Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-21-52196435

    Address:No.2 Floor,No.979 Yunhan Rd,Nicheng,Pudong New Area,Shanghai,China

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  • Montelukast sodium    manufacturer with low price

  • Casno:

    151767-02-1

    MSDS/COA Download

    Montelukast sodium manufacturer with low price

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

    Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd (JL Pharm) is established in 2012 at the beautiful West Lake – Hangzhou city, China. The company's main business includes R&D, Produ

  •  Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-571-85829053

    Address:Rm A606, Fuyi Center, jianqiao street, Jianggan Area

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  • High purity Montelukast sodium powder cas no. 151767-02-1

  • Casno:

    151767-02-1

    High purity Montelukast sodium powder cas no. 151767-02-1

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 20.0-30.0/Kilogram

    Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

    Baoji Guokang Healthchem co.,ltd located in Baoji High-tech Zone,is epitomizing international,cooperative and honest.We are a young company full of action and energy,and our profes

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     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-917-3909592

    Address:China

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  • Montelukast sodium

  • Casno:

    151767-02-1

    Montelukast sodium

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    SUNSANTA We are one of the leading exporters in China in the fields of active pharma ingredients including oncology drug, prostaglandin, anti-HIV drug, cardiovascular drug, diabetes drug, anti-inflammatory drug, urinary system drug, cosmetics

    Changzhou Sunsanta Chemical Co.,Ltd is located in changzhou,jiangsu,china, it is dedicated to developing, manufacturing and marketing of pharmaceutical intermediates, APIs and Fin

  •  Changzhou Sunsanta Chemical Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-519-83980506

    Address:RM 601,BUILDING 38,NO.98 HONGBEI ROAD,WUJIN,CHANGZHOU,JIANGSU,CHINA

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  • Montelukast sodium CAS No. 151767-02-1

  • Casno:

    151767-02-1

    MSDS/COA Download

    Montelukast sodium CAS No. 151767-02-1

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 1000.0-1500.0/Kilogram

    Product Name: Montelukast sodium Synonyms: singulair;MONTELUKAST NA;MONTELUKAST SODIUM;mk-476;2-[1-[[1-[3-[2-[(7-chloro-2-quinolyl)]vinyl]phenyl]-3-[2-(1-hydroxy-1-methyl-ethyl)phenyl]-propyl]sulfanylme

    Hebei Guanlang Biotechnology Co., Ltd. belongs to Guanlang Group,which was founded in 2007 , located in Shijiazhuang city which is the capital of Hebei Province and hub sector amon

  •  Hebei Guanlang Biotechnology Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+8619930503256

    Address:No.66, Yuhua West Road

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  • Montelukast sodium

  • Casno:

    151767-02-1

    Montelukast sodium

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

    Shandong Hanjiang Chemical Co., Ltd. is located in Qilu Petrochemical Industrial Park, Zibo City, Shandong Province, involving pesticide, medicine, chemical industry, coating, dy

  •  Shandong Hanjiang Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:18369939125

    Address:95A, Xingyuan East Road, Zhangdian District

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  • Montelukast sodium CAS 151767-02-1

  • Casno:

    151767-02-1

    Montelukast sodium CAS 151767-02-1

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    Company introduce: Wuhan Monad Medicine Tech Co.,LTD is located in Hubei province of China.We specialized in active pharmaceutical ingredient,pharmaceutical intermediates,veterinary drugs and agrochemicals. We have strong professional res

    Wuhan Monad Medicine Tech Co.,LTD is a research and development, production, sales in one high-tech company, own about 100 kinds of products, can provide about more than 30000 kind

  •  Wuhan Monad Medicine Tech Co.,LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+8613397160123

    Address:13th Floor, Tower B, Century Plaza, Zhongnan Road, Wuchang District, Wuhan, China.

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  • Montelukast sodium

  • Casno:

    151767-02-1

    Montelukast sodium

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Betterbiochem is specialized in APIs, pharmaceutical intermediates & fine chemicals. 1. The best quality, competitive price. 2. The best service before or after shipment. 3. Rich experience in export operation. 4. Rich experience in

    Shanghai BetterBioChem Co., Ltd. specializes in research, production of APIs, building blocks and key pharmaceutical intermediates. We provide our products from milligrams to kilog

  •  Shanghai BetterBioChem Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-18013506594

    Address:No. 8 Building, 18 nong, Xi Yingnan Road, Pudong, Shanghai,China

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  • ISO 9001   National Research Platform CAS No.  151767-02-1

  • Casno:

    151767-02-1

    ISO 9001 National Research Platform CAS No. 151767-02-1

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    1. Subsidiary of Institute of Chemistry, Henan Academy of Sciences, national research platform;2. About 30 years’ experience in this field since 1983;3. An experienced R&D team consisting of Doctors and Masters;4. Various types of analytical instrume

    Zhengzhou Kingorgchem Chemical Technology Co., Ltd. was founded on the basis of Organophosphorus Chemistry Lab of Institute of Chemistry Henan Academy of Sciences in 2015. The

  •  Zhengzhou Kingorgchem Chemical Technology Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-371-65511936

    Address:NO.56,Hongzhuan Road

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  • Montelukast Sodium

  • Casno:

    151767-02-1

    Montelukast Sodium

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    Wuhan Sun-shine Bio-technology Corporation Limited is specializing in the anticancer, antitumor,heart head blood-vessel,pharmaceutical intermediates,fine Chemicals production and customization. Company has strong ability of research and development

    Wuhan Sun-shine Bio-technology Corporation Limited (Shanghai Sun-shine Chemical Technology Corporation Limited) is a high-tech enterprise engaged inR&D and sales of related compoun

  •  Wuhan Sun-shine Bio-technology Corporation Limited

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-27-65522452

    Address:No. 388 Gaoxin Road(No. 2), East Lake Hi-tech Development Zone, Wuhan, Hubei Province, PRC

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  • Montelukast sodium

  • Casno:

    151767-02-1

    Montelukast sodium

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 1.0-100000.0/Kilogram

    Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

    AFINE CHEMICALS LIMITED is specialized in the fine chemicals and pharmaceuticals and we have enjoyed great popularity in world markets. Since 2005, we have been rapidly growing to

  •  Afine Chemicals Limited

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-85134551

    Address:No. 206 Zhen Hua Road, Hangzhou 310030, Zhejiang, China

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  • Montelukast Sodium

  • Casno:

    151767-02-1

    MSDS/COA Download

    Montelukast Sodium

    Min.Order: 10 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Min Order 10 Gram Supply Ability

    We, Jilin Tely Imp & Exp Co., Ltd. mainly supply and export products including: pharmaceutical raw materials,Chemical reagents, Food additives, pharmaceutical and pesticide interme

  •  Jilin Tely Imp.& Exp.Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-431-81915458

    Address:Room 302, 47 Changping Street, Chaoyang District, Changchun, Jilin Province,China

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  • Montelukast Sodium 151767-02-1

  • Casno:

    151767-02-1

    Montelukast Sodium 151767-02-1

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 10.0-10.0/Kilogram

    Appearance:off-white to white solid Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for Synthesis API and Research Transportation:As customer request Port:Qingda

    Triumph International Development Limilted is engaged in the API, pharmaceutical intermediates research and developmen.Adhering to the "customer first" business philosophy,we suppl

  •  Triumph International Development Limilted

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-536-7971999

    Address:Yinhai Road,Shouguang

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  • Montelukastsodium 151767-02-1

  • Casno:

    151767-02-1

    Montelukastsodium 151767-02-1

    Min.Order: 1 Gram

    FOB Price:  USD $ 1.0-1.0/Gram

    The company is a high-tech enterprise providing comprehensive customer service for pharmaceutical companies at home and abroad in accordance with international standards. Our business includes research, development, process optimization and product

    Prime Molecular Co., Ltd. is an advanced chemical intermediates manufacture with ?two R&D centers and two production sites in China, all well-equipped with dedicated and profession

  •  PRIME MOLECULAR CO.,LIMITED

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:0852-95636137

    Address:Hong Kong

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  • Good Price Powder Montelukast Sodium

  • Casno:

    151767-02-1

    Good Price Powder Montelukast Sodium

    Min.Order: 1 Gram

    FOB Price:  USD $ 1.0-5.0/Gram

    Strong backup of facotry: high R&D ability, favorable quality and competitive price 2. Stock avaliability 3. Flexible business way, like payment term and product delivery 4. Fast response 24*7 5. A good troubleshooter/very positive atti

    Beijing Yibai Biotechnology Co., Ltd, backed up with factory toppest support with high R&D ability, we have confidence to make you more competitive on market. Yibai is devoting fo

  •  Beijing Yibai Biotechnology Co., Ltd

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-010-60404860

    Address:Xuhui Plaza, Shunyi district, Beijing

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  • Montelukast sodium

  • Casno:

    151767-02-1

    Montelukast sodium

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

    J&H Chemical is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other

  •  Hangzhou J&H Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-87396432

    Address:No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China

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  • High Quality Montelukast Sodium

  • Casno:

    151767-02-1

    High Quality Montelukast Sodium

    Min.Order: 1 Gram

    FOB Price:  USD $ 1.0-1.0/Gram

    Qingdao Sigma Chemical Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, peptide,Nootropis etc API, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc. Our Labo

    SHANDONG SIGMACHEMICAL is mainly engaged in R&D, manufacturing and marketing pharmaceuticals, chemical intermediates, Biochemicals, Veterinary medicines and Nutrition products. Wit

  •  Qingdao Sigma Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:0532-80916960

    Address:shandong qingdao

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  • Montelukast sodium

  • Casno:

    151767-02-1

    Montelukast sodium

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 100.0-100.0/Kilogram

    HangYu Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. HangYu Chemical consis

    Zibo HangYu Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals

  •  Zibo Hangyu Import&Export Co., Ltd

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-15988566987

    Address:Room1701, Tianxing Building,Licheng district, jinan, Shandong, China

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Montelukast sodium, its cas register number is 151767-02-1. It also can be called Singulair; montelukast na; montelukast sodium; 2-[1-[[1-[3-[2-[(7-chloro-2-quinolyl)]vinyl]phenyl]-3-[2-(1-hydroxy-1-methyl-ethyl)phenyl]-propyl]sulfanylmethyl]cyclopropyl]acetic acid sodium salt; montelukast, sodium salt. Montelukast sodium is a hygroscopic, optically active, white to off-white powder. Montelukast sodium is freely soluble in ethanol, methanol, and water and practically insoluble in acetonitrile. The empirical formula is C35H35CINNaO3S, and its molecular weight is 608.18. Montelukast sodium is a selective leukotriene D4-receptor antagonist, can be used as an antiasthmatic treatment of asthma and to relieve symptoms of seasonal allergies.

Physical properties about Montelukast sodium are: (1)ACD/LogP: 7.799; (2)# of Rule of 5 Violations: 2; (3)ACD/LogD (pH 5.5): 6.99; (4)ACD/LogD (pH 7.4): 5.19; (5)ACD/BCF (pH 5.5): 76510.22; (6)ACD/BCF (pH 7.4): 1223.10; (7)ACD/KOC (pH 5.5): 63978.22; (8)ACD/KOC (pH 7.4): 1022.76; (9)#H bond acceptors: 4; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 13; (12)Flash Point: 407.7 °C; (13)Enthalpy of Vaporization: 114.78 kJ/mol; (14)Boiling Point: 750.5 °C at 760 mmHg; (15)Vapour Pressure: 1.17E-23 mmHg at 25°C

You can still convert the following datas into molecular structure:
(1)InChI=1S/C35H36ClNO3S.Na/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29;/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39);/q;+1/p-1/b15-10+;/t32-;/m1./s1;
(2)InChIKey=LBFBRXGCXUHRJY-HKHDRNBDSA-M;
(3)SmilesC1(CC1)(CS[C@@H](c1cc(\C=C\c2nc3c(ccc(c3)Cl)cc2)ccc1)CCc1c(cccc1)C(C)(C)O)CC(=O)[O-].[Na+]

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