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32897-26-0

Basic Information
CAS No.: 32897-26-0
Name: 1-Ethyl-3(3-dimethylamino)urea
Article Data: 6
Molecular Structure:
Molecular Structure of 32897-26-0 (1-Ethyl-3(3-dimethylamino)urea)
Formula: C8H19 N3 O
Molecular Weight: 173.258
Synonyms: 1-Ethyl-3-(3-dimethylaminopropyl)urea
Density: 0.948g/cm3
Boiling Point: 316.5°C at 760 mmHg
Flash Point: 145.2°C
Solubility: Soluble in water.
PSA: 44.37000
LogP: 1.03900
Synthetic route
2016-42-4

tetradecylamine

28393-02-4

10,12-docosadiynedioic acid

25952-53-8

1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride

A

N1,N22-ditetradecyldocosa-10,12-diynediamide

B

32897-26-0

1-ethyl-3-(3-dimethylaminopropyl)carbodiimide

Conditions
ConditionsYield
With dmap In chloroform at 25℃; for 20h;A 92.6%
B n/a
124-22-1

n-Dodecylamine

28393-02-4

10,12-docosadiynedioic acid

25952-53-8

1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride

A

N1,N22-didodecyldocosa-10,12-diynediamide

B

32897-26-0

1-ethyl-3-(3-dimethylaminopropyl)carbodiimide

Conditions
ConditionsYield
In chloroform at 25℃; for 20h; Solvent; Reagent/catalyst;A 85%
B n/a
28393-02-4

10,12-docosadiynedioic acid

25952-53-8

1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride

765-30-0

Cyclopropylamine

A

N1,N22-dicyclopropyldocosa-10,12-diynediamide

B

32897-26-0

1-ethyl-3-(3-dimethylaminopropyl)carbodiimide

Conditions
ConditionsYield
With dmap In acetone at 25℃; for 20h;A 84.2%
B n/a
870-46-2

t-butoxycarbonylhydrazine

61621-71-4

dodec-6-ynedioic acid

25952-53-8

1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride

A

C22H38N4O6

B

32897-26-0

1-ethyl-3-(3-dimethylaminopropyl)carbodiimide

Conditions
ConditionsYield
With dmap In tetrahydrofuran at 25℃;A 76%
B n/a
28393-02-4

10,12-docosadiynedioic acid

108-91-8

cyclohexylamine

25952-53-8

1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride

A

C34H56N2O2

B

32897-26-0

1-ethyl-3-(3-dimethylaminopropyl)carbodiimide

Conditions
ConditionsYield
With dmap In tetrahydrofuran at 25℃; for 20h;A 65.3%
B n/a
192332-48-2

N'-hydroxy-4-nitrobenzimidamide

25952-53-8

1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride

A

1261168-15-3

N-ethyl-3-(4-nitrophenyl)-1,2,4-oxadiazol-5-amine

B

1261168-16-4

N1,N1-dimethyl-N3-[3-(4-nitrophenyl)-1,2,4-oxadiazol-5-yl]propane-1,3-diamine

C

32897-26-0

1-ethyl-3-(3-dimethylaminopropyl)carbodiimide

Conditions
ConditionsYield
Stage #1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride With sodium carbonate In water; toluene for 0.0833333h;
Stage #2: N'-hydroxy-4-nitrobenzimidamide With oxygen In toluene for 4h; Reflux; Air atmosphere;
A 65%
B 28%
C n/a
19227-13-5

p-toluamidoxime

25952-53-8

1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride

A

1041005-85-9

N-ethyl-3-p-tolyl-1,2,4-oxadiazol-5-amine

B

1041005-86-0

N1,N1-dimethyl-N3-(3-p-tolyl-1,2,4-oxadiazol-5-yl)propane-1,3-diamine

C

32897-26-0

1-ethyl-3-(3-dimethylaminopropyl)carbodiimide

Conditions
ConditionsYield
Stage #1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride With sodium carbonate In water; toluene for 0.0833333h;
Stage #2: p-toluamidoxime With oxygen In toluene for 4h; Reflux; Air atmosphere;
A 61%
B 27%
C n/a
25952-53-8

1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride

613-92-3

N-hydroxybenzenecarboximidamide

A

1041005-83-7

N1,N1-dimethyl-N3-(3-phenyl-1,2,4-oxadiazol-5-yl)propane-1,3-diamine

B

16219-35-5

N-ethyl-3-phenyl-1,2,4-oxadiazol-5-amine

C

32897-26-0

1-ethyl-3-(3-dimethylaminopropyl)carbodiimide

Conditions
ConditionsYield
Stage #1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride With sodium carbonate In water; toluene for 0.0833333h;
Stage #2: N-hydroxybenzenecarboximidamide With oxygen In toluene for 4h; Reflux; Air atmosphere;
A 31%
B 60%
C n/a
25952-53-8

1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride

6965-39-5

2-(4-chlorophenyl)-N'-hydroxyacetimidamide

A

1247600-99-2

3-(4-chlorobenzyl)-N-ethyl-1,2,4-oxadiazol-5-amine

B

C14H19ClN4O

C

32897-26-0

1-ethyl-3-(3-dimethylaminopropyl)carbodiimide

Conditions
ConditionsYield
Stage #1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride With sodium carbonate In water; toluene for 0.0833333h;
Stage #2: 2-(4-chlorophenyl)-N'-hydroxyacetimidamide With oxygen In toluene for 4h; Reflux; Air atmosphere;
A 59%
B n/a
C n/a
5373-87-5

4-methoxybenzamidoxime

25952-53-8

1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride

A

1031930-94-5

N-ethyl-3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-amine

B

1041005-84-8

C14H20N4O2

C

32897-26-0

1-ethyl-3-(3-dimethylaminopropyl)carbodiimide

Conditions
ConditionsYield
Stage #1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride With sodium carbonate In water; toluene for 0.0833333h;
Stage #2: 4-methoxybenzamidoxime With oxygen In toluene for 4h; Reflux; Air atmosphere;
A 55%
B n/a
C n/a
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