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| CAS No.: | 7005-47-2 |
|---|---|
| Name: | 2-DIMETHYLAMINO-2-METHYL-1-PROPANOL |
| Article Data: | 11 |
| Molecular Structure: | |
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|
|
| Formula: | C6H15 N O |
| Molecular Weight: | 117.191 |
| Synonyms: | 2-(Dimethylamino)-2-methyl-1-propanol;2-(Dimethylamino)-2-methylpropyl alcohol;2-(N,N-Dimethylamino)-2-methyl-1-propanol; DMAMP; DMAMP 80;N,N-Dimethyl-2-amino-2-methylpropan-1-ol; NSC 17706; T-Amine WR 500 |
| Density: | 0.95g/mLat 20°C(lit.) |
| Melting Point: | 19°C |
| Boiling Point: | 61°C20mm Hg |
| Flash Point: | 145°F |
| Solubility: | 1000g/L at 20℃ |
| Hazard Symbols: | C |
| Risk Codes: | 34-35 |
| Safety: | Poison by intraperitoneal route. When heated to decomposition it emits toxic fumes of NOx. |
| PSA: | 23.47000 |
| LogP: | 0.31890 |
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| Conditions | Yield |
|---|---|
| With formic acid at 80℃; for 24h; | 46% |
| With formic acid; water | |
| With titanium(IV) isopropylate; sodium tetrahydroborate 1.) diglyme, 60 deg C, 30 min then r.t., 30 min; 2.) diglyme, r.t., 3 h then 60 deg C, 3 h; Yield given. Multistep reaction; | |
| With sodium tetrahydroborate; zinc(II) chloride 1.) CH2Cl2, RT, 1 h, 2.) CH2Cl2, 11 h; Yield given. Multistep reaction; | |
| Stage #1: formaldehyd; 2-Amino-2-methyl-1-propanol With formic acid In water at 0 - 90℃; for 5h; Stage #2: With sodium hydroxide; water pH=14; |
| Conditions | Yield |
|---|---|
| (methylation); |
| Conditions | Yield |
|---|---|
| Stage #1: 2-nitro-2-methylpropanol With hydrogen Stage #2: formaldehyd | |
| With hydrogen In methanol at 100℃; Autoclave; |
| Conditions | Yield |
|---|---|
| In benzene at 60℃; | 100% |
| In benzene at 60℃; | 28.3 g |
- 7005-47-2
2-dimethylamino-2-methylpropan-1-ol
- 74-88-4
methyl iodide
- 17199-19-8
2-(1-hydroxy-2-methyl)propyltrimethylammonium iodide
| Conditions | Yield |
|---|---|
| In isopropyl alcohol at 20 - 45℃; for 4h; Inert atmosphere; | 94% |
- 7005-47-2
2-dimethylamino-2-methylpropan-1-ol
- 540-72-7
sodium thiocyanide
- 6046-93-1
copper(II) acetate monohydrate
- 500128-69-8
[Cu((CH3)4NCCH2O)(NCS)]2
| Conditions | Yield |
|---|---|
| In methanol MeOH soln. of NaNCS was added to MeOH soln. of Cu(OAc)2*H2O and ligand, allowed to stand at 25°C for several ds; filtered, dried in vacuo; elem. anal.; | 90% |
| Conditions | Yield |
|---|---|
| In methanol MeOH soln. of CuCl2 was added to MeOH soln. of ligand, allowed to stand at 25°C for several ds; filtered, dried in vacuo; elem. anal.; | 90% |
- 7005-47-2
2-dimethylamino-2-methylpropan-1-ol
- 78676-35-4
benzo[b]thiophene-3-carbonyl azide
| Conditions | Yield |
|---|---|
| In benzene Heating; | 80% |
- 897441-42-8
N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-7-fluoro-6-nitroquinazolin-4-amine
- 7005-47-2
2-dimethylamino-2-methylpropan-1-ol
| Conditions | Yield |
|---|---|
| With potassium tert-butylate In dimethyl sulfoxide at 25℃; for 2h; | 77% |
- 39827-12-8
benzothiophene-3-carbonyl chloride
- 7005-47-2
2-dimethylamino-2-methylpropan-1-ol
| Conditions | Yield |
|---|---|
| In benzene Heating; | 70% |
- Total:28 Page 1 of 1 1
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Chemistry
Chemistry informtion about 2-Dimethylamino-2-Methyl-1-Propanol (CAS NO.7005-47-2) is:
IUPAC Name: 2-(Dimethylamino)-2-Methylpropan-1-Ol
Synonyms: Dmamp-80(Tm) ; 2-(N,N-Dimethylamino)Isobutanol ; 2-Dimethylaminoisobutanol ; 2-Dimethylamino-2-Methyl-1-Propanol ; 2-(Dimethylamino)-2-Methyl-1-Propano ; 2-(Dimethylamino)-2-Methylpropanol ; 2-(N,N-Dimethylamino)-2-Methyl-1-Propanol ; 2-Dimethylamino-2-Methyl-1-Propano
MF: C6H15NO
MW: 117.19
EINECS: 230-279-6
Density: 0.885 g/cm3
Flash Point: 39.9 °C
Boiling Point: 151 °C at 760 mmHg
Vapour Pressure: 1.41 mmHg at 25°C
Enthalpy of Vaporization: 45.18 kJ/mol
Refractive Index: n20/D 1.447
Following is the molecular structure of 2-Dimethylamino-2-Methyl-1-Propanol (CAS NO.7005-47-2) is:
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 25mg/kg (25mg/kg) | National Technical Information Service. Vol. AD277-689, |
Consensus Reports
Reported in EPA TSCA Inventory.
Safety Profile
Safty information about 2-Dimethylamino-2-Methyl-1-Propanol (CAS NO.7005-47-2) is:
Poison by intraperitoneal route. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:
C
Risk Statements:
R34:Causes burns.
Safety Statements:
S23:Do not breathe vapour.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2735 8/PG 3
RTECS: UB3325000
F:
F 10: Keep under argon.
F 34: Sensitive to CO2.
HazardClass: 3.2
PackingGroup: III