CAS No.74-87-3,Methyl chloride Suppliers,MSDS download

Products Categories

Pharmaceutical (24)
Organic Chemicals (12)
Others (6)
Reagent (4)
Materials (2)
Basic Inorganic Chemicals (1)

Basic Information

Molecular Structure:
CAS No.:	74-87-3
Name:	Methyl chloride
Article Data:	719
Cas Database

Formula:	CH₃Cl
Molecular Weight:	50.4878
Synonyms:	chloromethane;
EINECS:	200-817-4
Density:	0.895 g/cm³
Melting Point:	-97 °C
Boiling Point:	-24.2oC
Flash Point:	-46oC
Appearance:	colourless gas with a minorly sweet odor
Hazard Symbols:	F+,Xn,T,F
Risk Codes:	12-40-48/20
Safety:	9-16-33
Transport Information:	UN 1993 3/PG 1
PSA:	0.00000
LogP:	0.85500

Related products

Synthetic route

: 1928-38-7
methyl 2,4-dichlorophenoxyacetate

A: 94-75-7
2,4-Dichlorophenoxyacetic acid

B: 74-87-3
methylene chloride

Conditions

Conditions	Yield
With hydrogenchloride; zinc(II) chloride In water at 140℃; for 4h; Reagent/catalyst; Temperature;	A 99.6% B 98.1%

: 756-79-6
dimethyl methane phosphonate

A: 676-97-1
methylphosphonic acid dichloroanhydride

B: 74-87-3
methylene chloride

Conditions

Conditions	Yield
With thionyl chloride; N-Formylpiperidine for 19h; Heating; various conditions and cactalasts investigated;	A 99.2% B n/a

: 54705-23-6
methyl o-(N-methylcarbamoyl)phenyl sulphoxide

A: 2527-66-4
2-methyl-1,2-benzisothiazole-3(2H)-one

B: 74-87-3
methylene chloride

Conditions

Conditions	Yield
With thionyl chloride In tetrachloromethane for 5h; Heating;	A 99% B n/a

: [PdCl(N,N′-di-metyl-2,11-diaza[3,3](2,6)pyridinophane)(CH3)](2+)

: 56-34-8
tetraethylammonium chloride

A: 74-87-3
methylene chloride

: 1414791-67-5
[PdCl2(N,N-di-metyl-2,11-diaza[3,3](2,6)pyridinophane)]

Conditions

Conditions	Yield
In acetonitrile at 20℃; for 1h; Mechanism; Darkness;	A 99% B 99%

...Expand

: 75-44-5
phosgene

: 104953-88-0
2,3-bis(dimethylamino)quinol-4-one

A: 74-87-3
methylene chloride

B: 104953-90-4
4-Dimethylamino-3-methyl-3H-oxazolo[4,5-c]quinolin-2-one

Conditions

Conditions	Yield
With triethylamine In dichloromethane for 3h; Product distribution; Ambient temperature; aminoquinolones with COCl2;	A n/a B 98%
With triethylamine In dichloromethane for 3h; Ambient temperature;	A n/a B 98%

...Expand

: 79054-68-5
N-phenyl-2-(methylsulfinyl)benzamide

A: 2527-03-9
2-phenyl-1,2-benzisothiazolin-3-one

B: 74-87-3
methylene chloride

Conditions

Conditions	Yield
With thionyl chloride In dichloromethane for 0.166667h; Heating;	A 98% B n/a

: 79054-66-3
N-Cyclohexyl-2-methanesulfinyl-benzamide

A: 74-87-3
methylene chloride

B: 2527-02-8
2-cyclohexyl-1,2-benzisothiazol-3(2H)-one

Conditions

Conditions	Yield
With thionyl chloride In dichloromethane Heating;	A n/a B 98%

: 79054-69-6
2-Methanesulfinyl-N-p-tolyl-benzamide

A: 74-87-3
methylene chloride

B: 2514-30-9
2-(4-tolyl)-1,2-benzisothiazol-3-one

Conditions

Conditions	Yield
With thionyl chloride In dichloromethane Heating;	A n/a B 98%

: 79054-67-4
N-Benzyl-2-methanesulfinyl-benzamide

A: 74-87-3
methylene chloride

B: 2514-36-5
2-benzylbenzo[d]isothiazol-3(2H)-one

Conditions

Conditions	Yield
With thionyl chloride In dichloromethane Heating;	A n/a B 98%

: 79054-64-1
N-Isopropyl-2-methanesulfinyl-benzamide

A: 74-87-3
methylene chloride

B: 2-isopropyl-1,2-benzisothiazolin-3-one

Conditions

Conditions	Yield
With thionyl chloride In dichloromethane Heating;	A n/a B 97%

Downstream Products

22611-72-9

74-83-9

1624-62-0

993-16-8

345-89-1

75-83-2

506-77-4

4957-14-6

Country:
Business Type:
All

Lab/Research institutions

Trading Company

Manufacturers

Other
Certificate:
Manufacturer

Enterprise Authentication

ISO

GMP

FDA

HALAL

Display:default sort
Suppiers of more reward points first

New supplier

Total:43 Page 1 of 2 1 2 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 74-87-3

Consensus Reports

IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 246.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 41 ,1986,p. 161.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 41 ,1986,p. 161.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

Standards and Recommendations

OSHA PEL: TWA 50 ppm; STEL 100 ppm
ACGIH TLV: TWA 50 ppm; STEL 100 ppm; Not Classifiable as a Human Carcinogen
DFG MAK: 50 ppm (100 mg/m³); Suspected Carcinogen
NIOSH REL: (Monohalomethanes) TWA Reduce to lowest level
DOT Classification: 2.1; Label: Flammable Gas

Analytical Methods

For occupational chemical analysis use NIOSH: Methyl Chloride, 1001.

Specification

The Methyl chloride, with the CAS registry number 74-87-3 and EINECS registry number 200-817-4, has the systematic of chloromethane. And the molecular formula of this chemical is CH₃Cl. It is the most abundant organohalogen-anthropogenic or natural–in the atmosphere. It is a kind of colourless gas with a minorly sweet odor, and belongs to the following product categories: Refrigerants; Organics; CCosmetics; CFCsAlphabetic; Allergens; Alpha Sort; C; CH; Volatiles/ Semivolatiles; Alkyl; Halogenated Hydrocarbons; Organic Building Blocks. In addition, it should be stored at 2-8°C.

The physical properties of Methyl chloride are as following: (1)ACD/LogP: 1.11; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.113; (4)ACD/LogD (pH 7.4): 1.113; (5)ACD/BCF (pH 5.5): 4.129; (6)ACD/BCF (pH 7.4): 4.129; (7)ACD/KOC (pH 5.5): 96.046; (8)ACD/KOC (pH 7.4): 96.046; (9)#H bond acceptors: 0; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 0 Å²; (13)Index of Refraction: 1.331; (14)Molar Refractivity: 11.531 cm³; (15)Molar Volume: 56.427 cm³; (16)Polarizability: 4.571×10^-24cm³; (17)Surface Tension: 14.643 dyne/cm; (18)Density: 0.895 g/cm³; (19)Enthalpy of Vaporization: 21.902 kJ/mol; (20)Vapour Pressure: 4074.091 mmHg at 25°C.

Preparation of Methyl chloride: Large amounts of Methyl chloride are produced naturally in the oceans by the action of sunlight on biomass and chlorine in sea foam. However, all Methyl chloride that is used in industry is produced synthetically. It can be prepared by reacting methanol with hydrogen chloride:
CH₃OH + HCl → CH₃Cl + H₂O

Uses of Methyl chloride: It was widely used as refrigerant, but due to its toxicity and flammability, its use has been discontinued. It is used as a chemical intermediate in the production of silicone polymers. It is also used as a solvent in the manufacture of butyl rubber and in petroleum refining. What's more, it also used as a methylating and chlorinating agent in organic chemistry.

You should be cautious while dealing with this chemical. It is a kind of extremely flammable chemical, and has danger of serious damage to health by prolonged exposure through inhalation. What's more, it may cause carcinogenic effect. Therefore, you had better take the following instructions: Keep container in a well-ventilated place; Keep away from sources of ignition - No smoking; Take precautionary measures against static discharges.

You can still convert the following datas into molecular structure:
(1)SMILES: CCl
(2)InChI: InChI=1/CH3Cl/c1-2/h1H3
(3)InChIKey: NEHMKBQYUWJMIP-UHFFFAOYAW

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LCLo	inhalation	129mg/m³/4H (129mg/m³)	BEHAVIORAL: GENERAL ANESTHETIC LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Archiv fuer Hygiene und Bakteriologie. Vol. 116, Pg. 131, 1936.
dog	LCLo	inhalation	14661ppm/6H (14661ppm)	VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	National Institutes of Health, Bulletin. Vol. 191, Pg. 1, 1949.
guinea pig	LCLo	inhalation	20000ppm/2H (20000ppm)		Fluorine Chemistry Reviews. Vol. 1, Pg. 197, 1967.
human	LCLo	inhalation	20000ppm/2H (20000ppm)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: NAUSEA OR VOMITING	"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 386, 1969.
mouse	LC50	inhalation	2200ppm/6H (2200ppm)		Toxicology and Applied Pharmacology. Vol. 86, Pg. 93, 1986.
rat	LC50	inhalation	5300mg/m³/4H (5300mg/m³)		"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 82, 1982.
rat	LD50	oral	1800mg/kg (1800mg/kg)		"Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 86, 1986.