CAS No.9004-54-0,Dextran Suppliers

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Basic Information

Molecular Structure:
CAS No.:	9004-54-0
Name:	Dextran
Article Data:	13

Formula:	[C₆H₁₀O₅]_n
Molecular Weight:	396.42998
Synonyms:	T 40(polysaccharide);T 5 (polysaccharide);T 500;T 500 (carbohydrate);T 6;T 70;Low molecular dextran-L;Dextrans;Dextran 10;Dextran 1000;Dextran 110;T 70 (carbohydrate);a-Dextran;Dextran 15;Dextran 2000;Dextran 250;Dextran 40;Dextran 40000;Dextran 500;Dextran 70;Dextran 75;Dextran T 10;Dextran T100;Dextran T 2000;Dextran T 40;Dextran T 500;Dextran T 70;Dextranen;Dextraven;Eudextran;Gentran;Gentran 40;Infucoll;Intradex;LVD;Macrodex;Macrose;Oncovertin N;Onkotin;PL 1S;Plasmodex;Plavolex;Polyglusol;Rheomacrodex;Rheopolyglucin;Rheopolyglucine;Rheotran;Rondex;Rondex (polysaccharide);Serva G;T 110;T 110 (carbohydrate);T 150;T 20 (carbohydrate);T 250;T 250 (polysaccharide);T 4;T 4 (polysaccharide);T 40;
EINECS:	232-677-5
Melting Point:	-114.22oC
Boiling Point:	-85.05oC at 760 mm Hg
Solubility:	Soluble in water, dimethyl sulfoxide, ethylene glycol and glycerol.
Appearance:	white crystals or powder
Hazard Symbols:	Xi,Xn
Risk Codes:	20/21/22-36/37/38
Safety:	24/25-37/39-36-26
PSA:	276.52000
LogP:	-7.73040

Raw Materials

133-99-3

57-50-1

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Consensus Reports

Reported in EPA TSCA Inventory.

Specification

The systematic name of Dextran 70 is Dextran. With the CAS registry number 9004-54-0, it is also named as Low molecular dextran-L. The product's categories are Dextrins, Sugar & Carbohydrates; Carbohydrates D-FAlphabetic; DA - DH Biochemicals and Reagents; Biostabilization Agents Carbohydrates; Biostabilization Agents Biochemicals and Reagents; Carbohydrates A to; Carbohydrates D-FBiochemicals and Reagents; DA - DH Polymer Standards; Alphabetic; D; Dextran etc., and the other registry numbers are 11104-36-2; 11121-03-2; 12626-85-6; 128635-03-0; 37224-17-2; 60454-72-0; 86280-85-5; 9013-80-3; 9044-66-0; 911319-01-2. Besides, it is white crystals or powder, which should be stored in closed, cool and dry place at 2-8 °C. It is stable, and incompatible with strong oxidizing agents. In addition, its molecular formula is [C₆H₁₀O₅]_n.

Preparation and Uses of Dextran 70: this chemical can be prepared by microbial fermentation of Leyconostoc meseteroides. What's more, this chemical is used as an antithrombotic (anti-platelet), to reduce blood viscosity, and as a volume expander in anemia. it is also used in some eye drops as a lubricant, and in certain intravenous fluids to solubilise other factors, e.g. iron. Furthermore, it is in bead form used to aid in bioreactor applications. And it can be used to protect metal nanoparticles from oxidation and improve biocompatibility as a stabilising coating. Additionally, it can be used for industrial cell culture to make microcarriers.

When you are using this chemical, please be cautious about it as the following: it is harmful by inhalation, in contact with skin and if swallowed. You should avoid contact with skin and eyes. It is also irritating to eyes, respiratory system and skin. In case of contact with eyes, please rinse immediately with plenty of water and seek medical advice. And you should wear suitable protective clothing, gloves and eye/face protection.

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mammal (species unspecified)	LD50	unreported	13500mg/kg (13500mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Gematologiya i Transfuziologiya. Hematology and Transfusion Science. Vol. 31(10), Pg. 38, 1986.
mouse	LD50	intravenous	12100mg/kg (12100mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.
mouse	LD50	oral	> 12gm/kg (12000mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.
mouse	LD50	subcutaneous	13900mg/kg (13900mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.
rabbit	LD50	intravenous	17400mg/kg (17400mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.
rabbit	LD50	intravenous	208gm/kg (208000mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: CYANOSIS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 201, 1975.
rat	LD50	intravenous	6900mg/kg (6900mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.
rat	LD50	oral	> 3gm/kg (3000mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.
rat	LD50	subcutaneous	10700mg/kg (10700mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.
women	TDLo	intravenous	6mg/kg (6mg/kg)	CARDIAC: OTHER CHANGES VASCULAR: OTHER CHANGES SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	British Medical Journal. Vol. 2, Pg. 1502, 1976.

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