1071-38-1 Usage
Description
(Dimethylaminomethylene)dimethylammonium chloride, also known as N,N,N′,N′-tetramethylformamidinium chloride, is an amidine derivative with a unique chemical structure that features a dimethylamino group connected to a methylene bridge and a dimethylammonium group. (DIMETHYLAMINOMETHYLENE)DIMETHYLAMMONIUM CHLORIDE is known for its versatile reactivity and potential applications in various chemical syntheses.
Uses
Used in Chemical Synthesis:
(Dimethylaminomethylene)dimethylammonium chloride is used as a synthetic intermediate for the production of various organic compounds due to its unique reactivity and functional groups. It serves as a key building block in the synthesis of complex molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (Dimethylaminomethylene)dimethylammonium chloride is used as a reagent in the synthesis of aminomethylene hydantoins, which are important intermediates for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
(Dimethylaminomethylene)dimethylammonium chloride is also utilized in the agrochemical industry for the synthesis of thiohydantoins. These compounds are known for their insecticidal and fungicidal properties, making them valuable in the development of new pesticides.
Used in Polymer Industry:
In the polymer industry, (Dimethylaminomethylene)dimethylammonium chloride is used as a monomer in the synthesis of 2,2′-o-phenyl-enebis(1,3-dimethylguanidine). (DIMETHYLAMINOMETHYLENE)DIMETHYLAMMONIUM CHLORIDE can be used to create novel polymers with unique properties, such as enhanced thermal stability and mechanical strength.
Used in Solvent Production:
(Dimethylaminomethylene)dimethylammonium chloride is used as a starting material in the production of N,N-dimethylformamide di-tert-butyl acetal, a valuable solvent with applications in various chemical processes, including the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 1071-38-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,7 and 1 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1071-38:
(6*1)+(5*0)+(4*7)+(3*1)+(2*3)+(1*8)=51
51 % 10 = 1
So 1071-38-1 is a valid CAS Registry Number.
InChI:InChI=1/C5H13N2.ClH/c1-6(2)5-7(3)4;/h5H,1-4H3;1H/q+1;/p-1
1071-38-1Relevant articles and documents
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de Vries,L.
, p. 926 - 933 (1978)
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Toeniskoetter,R.H.,Killip,K.A.
, p. 690 - 694 (1964)
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Nickel-Catalyzed Enantioselective Cross-Coupling of N-Hydroxyphthalimide Esters with Vinyl Bromides
Suzuki, Naoyuki,Hofstra, Julie L.,Poremba, Kelsey E.,Reisman, Sarah E.
supporting information, p. 2150 - 2153 (2017/04/27)
An enantioselective Ni-catalyzed cross-coupling of N-hydroxyphthalimide esters with vinyl bromides is reported. The reaction proceeds under mild conditions and uses tetrakis(N,N-dimethylamino)ethylene as a terminal organic reductant. Good functional group tolerance is demonstrated, with over 20 examples of reactions that proceed with >90% ee.
Orthoamides and iminium salts LXXIV [1]. Reactions of N,N,N',N'- Tetramethyl-chloroformamidiniumChloride with metals
Kantlehner, Willi,Aichholz, Reiner,Karl, Martin
, p. 305 - 319 (2012/07/13)
N,N,N',N'-Tetramethyl-formamidinium chloride (2a) reacts with elemental sodium in various solvents to give N,N,N',N',N'',N''-hexamethyl-guanidinium chloride (4a). The reaction of 2a with potassium affords N,N,N',N',N'',N'',N''', N'''-octamethyl-oxamidinium dichloride (3a). From the reaction of 2a with magnesium in different solvents in general result mixtures of the salts 4a, 3a and N,N,N',N'-tetramethyl-formamidinium chloride (10a). The composition of these mixtures depends on the solvent and the reaction temperature. Similar results are obtained, when a zinc'copper couple is used instead of magnesium. Very likely from 2a and magnesium or zinc, respectively, organometallic intermediates 11, 12 are formed which could be trapped by aromatic aldehydes and phenylisocyanate. The salt 2a can be reductively coupled by a low-valent titanium reagent to give the oxamidinium salt 3a.
