Welcome to LookChem.com Sign In|Join Free

CAS

  • or

142770-42-1

142770-42-1

Post Buying Request

142770-42-1 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

142770-42-1 Usage

General Description

1-Chloro-4-propoxythioxanthone, also known as CPTX, is a chemical compound commonly used in the field of organic synthesis and photoinitiators for polymerization reactions. It is a thioxanthone derivative that possesses a chlorine atom at the first position and a propoxy group at the fourth position of the thioxanthone ring. CPTX is often utilized in the production of coatings, adhesives, and printing inks due to its ability to initiate polymerization when exposed to UV light. Additionally, CPTX has been studied for its potential application in photodynamic therapy for cancer treatment. Overall, 1-Chloro-4-propoxythioxanthone is a versatile chemical compound with various industrial and biomedical applications.

Check Digit Verification of cas no

The CAS Registry Mumber 142770-42-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,7,7 and 0 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 142770-42:
(8*1)+(7*4)+(6*2)+(5*7)+(4*7)+(3*0)+(2*4)+(1*2)=121
121 % 10 = 1
So 142770-42-1 is a valid CAS Registry Number.
InChI:InChI=1/C16H13ClO2S/c1-2-9-19-12-8-7-11(17)14-15(18)10-5-3-4-6-13(10)20-16(12)14/h3-8H,2,9H2,1H3

142770-42-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-chloro-4-propoxythioxanthen-9-one

1.2 Other means of identification

Product number -
Other names 1-chloro-4-propyloxy-thioxanthone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:142770-42-1 SDS

142770-42-1Synthetic route

1-chloro-4-hydroxy-9H-thioxanthen-9-one
59803-22-4

1-chloro-4-hydroxy-9H-thioxanthen-9-one

propyl bromide
106-94-5

propyl bromide

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

Conditions
ConditionsYield
With potassium carbonate at 80℃;95.4%
1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

1-chloro-4-hydroxy-9H-thioxanthen-9-one
59803-22-4

1-chloro-4-hydroxy-9H-thioxanthen-9-one

Conditions
ConditionsYield
Stage #1: 1-chloro-4-propoxy-9H-thioxanthen-9-one With boron tribromide In dichloromethane at -70℃;
Stage #2: With methanol		88%
With boron tribromide Ullmann Condensation;
1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

4-propoxy-1-chloro-9H-thioxanthen-9-one 10-oxide
591773-95-4

4-propoxy-1-chloro-9H-thioxanthen-9-one 10-oxide

Conditions
ConditionsYield
With ammonium cerium(IV) nitrate In water; acetonitrile at 20 - 25℃; for 2h;87%
With ammonium cerium(IV) nitrate In water; acetonitrile at 50℃; for 1h;72.7%
With ammonium cerium(IV) nitrate In water; acetonitrile at 20℃; for 2h;
1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

4-propoxy-1-chloro-9H-thioxanthen-9-one 10,10-dioxide

4-propoxy-1-chloro-9H-thioxanthen-9-one 10,10-dioxide

Conditions
ConditionsYield
With dihydrogen peroxide In water; acetic acid for 2h; Heating;56%
methanol
67-56-1

methanol

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

propan-1-ol-3-amine
156-87-6

propan-1-ol-3-amine

A

1-methoxy-4-propoxy-9H-thioxanthen-9-one
1351934-50-3

1-methoxy-4-propoxy-9H-thioxanthen-9-one

B

1-[(3-hydroxypropyl)amino]-4-propoxy-9H-thioxanthen-9-one
1351934-52-5

1-[(3-hydroxypropyl)amino]-4-propoxy-9H-thioxanthen-9-one

Conditions
ConditionsYield
With copper(I) oxide at 100℃; for 48h; Ullmann cross-coupling;A n/a
B 30%
(2R)-hydroxypropylamine
2799-16-8

(2R)-hydroxypropylamine

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

(R)-1-((2-hydroxypropyl)amino)-4-propoxy-9H-thioxanthen-9-one

(R)-1-((2-hydroxypropyl)amino)-4-propoxy-9H-thioxanthen-9-one

Conditions
ConditionsYield
With copper(l) iodide; potassium carbonate In methanol at 100℃; for 48h;23.62%
(S)-2-amino-4-methylpentan-1-ol
7533-40-6

(S)-2-amino-4-methylpentan-1-ol

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

(S)-1-((1-hydroxy-4-methylpentan-2-yl)amino)-4-propoxy-9H-thioxanthen-9-one

(S)-1-((1-hydroxy-4-methylpentan-2-yl)amino)-4-propoxy-9H-thioxanthen-9-one

Conditions
ConditionsYield
With copper(l) iodide; potassium carbonate In methanol at 100℃; for 48h;19.59%
2-amino-4-methyl-1-pentanol
7533-40-6, 16369-17-8, 53448-09-2, 502-32-9

2-amino-4-methyl-1-pentanol

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

(R)-1-((1-hydroxy-4-methylpentan-2-yl)amino)-4-propoxy-9H-thioxanthen-9-one

(R)-1-((1-hydroxy-4-methylpentan-2-yl)amino)-4-propoxy-9H-thioxanthen-9-one

Conditions
ConditionsYield
With copper(l) iodide; potassium carbonate In methanol at 100℃; for 48h;10.4%
(R)-2-amino-3-methylbutanol
4276-09-9

(R)-2-amino-3-methylbutanol

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

(R)-1-((1-hydroxy-3-methylbutan-2-yl)amino)-4-propoxy-9H-thioxanthen-9-one

(R)-1-((1-hydroxy-3-methylbutan-2-yl)amino)-4-propoxy-9H-thioxanthen-9-one

Conditions
ConditionsYield
With copper(l) iodide; potassium carbonate In methanol at 100℃; for 48h;10.24%
(S)-valinol
2026-48-4

(S)-valinol

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

(S)-1-((1-hydroxy-3-methylbutan-2-yl)amino)-4-propoxy-9H-thioxanthen-9-one

(S)-1-((1-hydroxy-3-methylbutan-2-yl)amino)-4-propoxy-9H-thioxanthen-9-one

Conditions
ConditionsYield
With copper(l) iodide; potassium carbonate In methanol at 100℃; for 48h;10.12%
(S)-1-amino-2-propanol
2799-17-9

(S)-1-amino-2-propanol

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

(S)-1-((2-hydroxypropyl)amino)-4-propoxy-9H-thioxanthen-9-one

(S)-1-((2-hydroxypropyl)amino)-4-propoxy-9H-thioxanthen-9-one

Conditions
ConditionsYield
With copper(l) iodide; potassium carbonate In methanol at 100℃; for 48h;7.86%
(R)-2-aminopropan-1-ol
35320-23-1

(R)-2-aminopropan-1-ol

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

(R)-1-((1-hydroxypropan-2-yl)amino)-4-propoxy-9H-thioxanthen-9-one

(R)-1-((1-hydroxypropan-2-yl)amino)-4-propoxy-9H-thioxanthen-9-one

Conditions
ConditionsYield
With copper(l) iodide; potassium carbonate In methanol at 100℃; for 48h;5.91%
(S)-Alaninol
2749-11-3

(S)-Alaninol

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

(S)-1-((1-hydroxypropan-2-yl)amino)-4-propoxy-9H-thioxanthen-9-one

(S)-1-((1-hydroxypropan-2-yl)amino)-4-propoxy-9H-thioxanthen-9-one

Conditions
ConditionsYield
With copper(l) iodide; potassium carbonate In methanol at 100℃; for 48h;1.97%
1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

4-propoxy-1-chloro-9-oxo-10-(4-heptoxyphenyl)-9H-thioxanthenium

4-propoxy-1-chloro-9-oxo-10-(4-heptoxyphenyl)-9H-thioxanthenium

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 87 percent / cerium ammonium nitrate / acetonitrile; H2O / 2 h / 20 - 25 °C
2: P2O5; methanesulfonic acid
View Scheme
4,4'-didodecyloxyphenyl sulfoxide
134216-06-1

4,4'-didodecyloxyphenyl sulfoxide

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

C52H70ClO4S2(1+)*F6Sb(1-)

C52H70ClO4S2(1+)*F6Sb(1-)

Conditions
ConditionsYield
Stage #1: 4,4'-didodecyloxyphenyl sulfoxide; 1-chloro-4-propoxy-9H-thioxanthen-9-one With sulfuric acid In chloroform; acetic anhydride at 10 - 20℃; for 48h;
Stage #2: With sodium hexafluoroantimonate In chloroform; water; acetic anhydride at 20℃; for 12h;
piperidine
110-89-4

piperidine

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

1-(piperidin-1-yl)-4-propoxy-9H-thioxanthen-9-one
1351934-53-6

1-(piperidin-1-yl)-4-propoxy-9H-thioxanthen-9-one

Conditions
ConditionsYield
With copper(I) oxide Ullmann cross-coupling;
DL-threonine
72-19-5, 80-68-2, 144-98-9, 632-20-2, 2676-21-3, 7004-04-8, 24830-94-2, 28954-12-3, 36676-50-3

DL-threonine

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

3-Hydroxy-2-[(9-oxo-4-propoxy-9H-thioxanthen-1-yl)amino]butanoic acid
1351934-55-8

3-Hydroxy-2-[(9-oxo-4-propoxy-9H-thioxanthen-1-yl)amino]butanoic acid

Conditions
ConditionsYield
With copper(I) oxide In 1-methyl-pyrrolidin-2-one; water Ullmann cross-coupling;
N-acetylpiperidine
13889-98-0

N-acetylpiperidine

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

1-(4-acetylpiperazin-1-yl)-4-propoxy-9H-thioxanthen-9-one
1351934-58-1

1-(4-acetylpiperazin-1-yl)-4-propoxy-9H-thioxanthen-9-one

Conditions
ConditionsYield
With copper(I) oxide; potassium carbonate In 1-methyl-pyrrolidin-2-one at 205℃; for 0.833333h; Ullmann cross-coupling; Microwave irradiation;
isoniazid
54-85-3

isoniazid

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

N'-(9-oxo-4-propoxy-9H-thioxanthen-1-yl)isonicotinohydrazide
1351934-61-6

N'-(9-oxo-4-propoxy-9H-thioxanthen-1-yl)isonicotinohydrazide

Conditions
ConditionsYield
With copper(I) oxide Ullmann cross-coupling;
valinol
16369-05-4

valinol

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

C21H25NO3S

C21H25NO3S

Conditions
ConditionsYield
With copper(I) oxide; potassium carbonate In methanol at 100℃; for 48h; Ullmann cross-coupling;
2-(1H-benzimidazol-2-yl)ethylamine
29518-68-1

2-(1H-benzimidazol-2-yl)ethylamine

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

1-[2-(1H-benzimidazole-2-yl)ethylamino]-4-propoxy-9H-thioxanthen-9-one
1351934-65-0

1-[2-(1H-benzimidazole-2-yl)ethylamino]-4-propoxy-9H-thioxanthen-9-one

Conditions
ConditionsYield
With copper(I) oxide In 1-methyl-pyrrolidin-2-one; water Ullmann cross-coupling;
1,2,3,4-tetrahydroisoquinolin-5-amine
115955-90-3

1,2,3,4-tetrahydroisoquinolin-5-amine

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

1-(5-Amino-3,4-dihydroisoquinolin-2(1H)-yl)-4-propoxy-9H-thioxanthen-9-one
1351934-63-8

1-(5-Amino-3,4-dihydroisoquinolin-2(1H)-yl)-4-propoxy-9H-thioxanthen-9-one

Conditions
ConditionsYield
With copper(I) oxide; potassium carbonate In 1-methyl-pyrrolidin-2-one at 205℃; for 0.833333h; Ullmann cross-coupling; Microwave irradiation;
C12H17NO6

C12H17NO6

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

C28H29NO8S

C28H29NO8S

Conditions
ConditionsYield
With copper(I) oxide In 1-methyl-pyrrolidin-2-one; water Ullmann cross-coupling;
sulfuric acid mono-(2-amino-ethyl ester)
926-39-6

sulfuric acid mono-(2-amino-ethyl ester)

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

2-[(9-Oxo-4-propoxy-9H-thioxanthen-1-yl)amino]ethyl hydrogen sulfate
1351934-62-7

2-[(9-Oxo-4-propoxy-9H-thioxanthen-1-yl)amino]ethyl hydrogen sulfate

Conditions
ConditionsYield
With copper(I) oxide Ullmann cross-coupling;
O-(p-nitrobenzyl)hydroxylamine
1944-96-3

O-(p-nitrobenzyl)hydroxylamine

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

1-(((4-nitrobenzyl)oxy)amino)-4-propoxy-9H-thioxanthen-9-one
1351934-69-4

1-(((4-nitrobenzyl)oxy)amino)-4-propoxy-9H-thioxanthen-9-one

Conditions
ConditionsYield
With copper(I) oxide Ullmann cross-coupling;
p-xylylidenediamine
539-48-0

p-xylylidenediamine

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

1-{[4-(Aminomethyl)benzyl]amino}-4-propoxy-9H-thioxanthen-9-one
1351934-59-2

1-{[4-(Aminomethyl)benzyl]amino}-4-propoxy-9H-thioxanthen-9-one

Conditions
ConditionsYield
With copper(I) oxide Ullmann cross-coupling;
2-(p-nitrophenyl)ethylamine
24954-67-4

2-(p-nitrophenyl)ethylamine

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

1-{[2-(4-nitrophenyl)ethyl]amino}-4-propoxy-9H-thioxanthen-9-one
1351934-68-3

1-{[2-(4-nitrophenyl)ethyl]amino}-4-propoxy-9H-thioxanthen-9-one

Conditions
ConditionsYield
With copper(I) oxide Ullmann cross-coupling;
2-nitro-4-ethoxyaniline
616-86-4

2-nitro-4-ethoxyaniline

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

1-[(4-Ethoxy-2-nitrophenyl)amino]-4-propoxy-9H-thioxanthen-9-one
1351934-70-7

1-[(4-Ethoxy-2-nitrophenyl)amino]-4-propoxy-9H-thioxanthen-9-one

Conditions
ConditionsYield
With copper(I) oxide; potassium carbonate In 1-methyl-pyrrolidin-2-one at 205℃; for 0.833333h; Ullmann cross-coupling; Microwave irradiation;
3,4-methylenedioxyphenylethylamine
1484-85-1

3,4-methylenedioxyphenylethylamine

1-chloro-4-propoxy-9H-thioxanthen-9-one
142770-42-1

1-chloro-4-propoxy-9H-thioxanthen-9-one

1-{[2-(1,3-benzodioxol-5-yl)ethyl]amino}-4-propoxy-9H-thioxanthen-9-one
1351934-66-1

1-{[2-(1,3-benzodioxol-5-yl)ethyl]amino}-4-propoxy-9H-thioxanthen-9-one

Conditions
ConditionsYield
With copper(I) oxide Ullmann cross-coupling;
Ullmann Condensation; Alkaline conditions; Microwave irradiation;

142770-42-1Relevant articles and documents

Preparation method of photoinitiator 1-chloro-4-propoxythioxanthone

-

Paragraph 0035; 0037; 0038, (2018/09/12)

The invention discloses a preparation method of a photoinitiator 1-chloro-4-propoxythioxanthone. The method comprises the following steps: step 1, carrying out condensation ring formation reaction: adding 2-mercaptobenzoic acid and p-chlorophenol into concentrated sulfuric acid and extracting to obtain a corresponding organic product; step 2, directly carrying out etherification reaction, withoutthe need of separation and purification: adding 1-halogenated propane and alkali into an obtained organic layer; finally, carrying out decompression and desolvation, de-coloring, filtering and vacuumdrying on an etherified product to obtain a final product, i.e., the photoinitiator 1-chloro-4-propoxythioxanthone. Compared with the prior art, the yield is greatly improved, reaction conditions aremoderate and post-treatment is simple; the preparation method is a production method suitable for industrialization.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 142770-42-1