926-39-6Relevant academic research and scientific papers
Cyclic process for producing taurine from monoethanolamine
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Page/Page column 13-14, (2022/03/22)
There is disclosed a cyclic process for producing taurine from monoethanolamine comprising the steps of: (a) recovering monoethanolamine sulfate from an aqueous mother liquor solution; (b) reacting the monoethanolamine sulfate with sulfuric acid to form an aqueous solution comprised of monoethanolamine bisulfate; (c) heating the aqueous solution comprised of the monoethanolamine sulfate and optionally added monoethanolamine sulfate to yield 2-aminoethyl hydrogen sulfate ester; (d) reacting the ester with ammonium sulfite or an alkali sulfite to yield taurine and ammonium or alkali sulfate; (e) separating taurine and ammonium or alkali sulfate to give an aqueous mother liquor solution; and (f) recovering the monoethanolamine sulfate from the aqueous mother liquor solution and recycling to the monoethanolamine sulfate to step (b).
Cyclic process for producing taurine from monoethanolamine
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Page/Page column 12-15, (2021/11/03)
There is disclosed a cyclic process for producing taurine from monoethanolamine comprising the steps of: (a) reacting monoethanolamine with ammonium sulfate in the recycling mother liquor to yield monoethanolamine sulfate; (b) reacting the monoethanolamine sulfate with sulfuric acid to form 2-aminoethyl hydrogen sulfate ester; (c) subjecting the 2-aminoethyl hydrogen sulfate ester to a sulfonation reaction with ammonium sulfite to yield taurine and ammonium sulfate; (d) separating the taurine and the ammonium sulfate by means of solid-liquid separation; (e) removing the excess ammonium sulfite from the mother liquor to obtain an aqueous solution comprised of ammonium sulfate and (f) returning the aqueous solution to step (a) to complete the cyclic process.
Synthesis method of taurine precursor 2-aminoethanol sulfate
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Paragraph 0027-0078, (2019/12/11)
The invention relates to a synthesis method of taurine precursor 2-aminoethanol sulfate, and the synthesis method takes ethanolamine as an initial raw material to synthesize the 2-aminoethanol sulfatein the presence of sulfuric acid and phase transfer catalyst tetrabutyl ammonium bromide. The synthesis method of the 2-aminoethanol sulfate has the advantages of shorter synthesis circuit and higherreaction efficiency; meanwhile, the obtained product has better purity and higher yield. In addition, the synthesis method does not need special production equipment with high price, has wide raw material sources and low price, thereby effectively reducing the production cost and obtaining good economic benefits.
Synthesis method and application of 3-benzyl-1,3-thiazolidine-2-thione
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Paragraph 0054, (2018/04/03)
The invention provides a synthesis method of 3-benzyl-1,3-thiazolidine-2-thione. The synthesis method comprises the following step of performing reaction on 1,3-thiazolidine-2-thione, an alkaline reagent and benzyl halide in a solvent to obtain the 3-benzyl-1,3-thiazolidine-2-thione. According to the synthesis method, an optimization condition of synthesizing the 3-benzyl-1,3-thiazolidine-2-thionethrough exploration, the yield of the 3-benzyl-1,3-thiazolidine-2-thione is 67.8 percent, and the purity reaches up to 99.99 percent. Further, when the 3-benzyl-1,3-thiazolidine-2-thione is synthesized with the method provided by the invention, 2-benzylthio-1,3-thiazolidine as an isomer can also be produced, and the two compounds both have higher activity in a herbicide and an insecticide. In addition, the invention also provides application of the 3-benzyl-1,3-thiazolidine-2-thione in the herbicide and the insecticide.
One-step synthesis of 6-acetamido-3-(N-(2-(dimethylamino) ethyl) sulfamoyl) naphthalene-1-yl 7-acetamido-4-hydroxynaphthalene-2-sulfonate and its characterization with 1D and 2D NMR techniques
Zhang, Wei
, p. 431 - 434 (2013/07/26)
A one-step method was reported for the synthesis of 6-acetamido-3-(N-(2- (dimethylamino) ethyl) sulfamoyl) naphthalene-1-yl 7-acetamido-4- hydroxynaphthalene-2-sulfonate by treating 7-acetamido-4-hydroxy-2- naphthalenesulfonyl chloride with equal moles of N, N-dimethylethylenediamine in acetonitrile in the presence of K2CO3. The chemical structure of the obtained compounds was characterized by MS, FTIR, 1H NMR, 13C NMR, gCOSY, TOCSY, gHSQC, and gHMBC. The chemical shift differences of 1H and 13C being δ 0.04 and 0.2, respectively, were unambiguously differentiated. Copyright 2013 John Wiley & Sons, Ltd. 6-Acetamido-3-(N-(2-(dimethylamino) ethyl) sulfamoyl) naphthalene-1-yl 7-acetamido-4-hydroxynaphthalene-2-sulfonate was prepared by a one-step method. The structure of the compound was elucidated by 1D and 2D NMR. The chemical shift differences of 1H and 13C being δ 0.04 and 0.2, respectively, were unambiguously differentiated. Copyright
Synthesis, crystal structure, and fungicidal activity of novel 1,5-diaryl-1H-pyrazol-3-Oxy derivatives containing oxyacetic acid or oxy(2-thioxothiazolidin-3-yl)ethanone moieties
Liu, Yuanyuan,He, Guangke,Kai, Chen,Li, Yufeng,Zhu, Hongjun
, p. 1370 - 1375 (2013/02/22)
A series of novel 1,5-diaryl-1H-pyrazol-3-oxy derivatives containing oxyacetic acid or oxy(2-thioxothiazolidin-3-yl)ethanone moieties were prepared from methyl 3-arylacrylates via a serial of reactions included addition-cyclization, oxidation, substitution, hydrolysis, and condensation. Their structures were confirmed by 1H-NMR, 13C-NMR, IR, and elemental analysis. In addition, the crystal structure of the compound 2-(1,5-diphenyl-1H-pyrazol-3-yloxy)-1-(2-thioxothiazolidin-3-yl)ethanone was determined by single crystal X-ray diffraction analysis. Bioassay results indicated that the compound 2-(5-(4-chlorophenyl)-1-phenyl-1H-pyrazol-3-yloxy)- 1-(2-thioxo-thiazolidin-3-yl)ethanone exhibited moderate inhibitory activity against Gibberella zeae at the dosage of 10 μg mL-1.
Reaction of 2-thiazolidinethione with halohydrocarbon: Synthesis of novel N-alkylated 2-thiazolidinethione and S-alkylated thiazoline derivatives
Liu, Yufa,Liu, Junwei,Liu, Xiuming
scheme or table, p. 275 - 278 (2011/06/10)
Reaction of 2-thiazolidinethione with halohydrocarbon in ethanol gave a series of N-alkylated 2-thiazolidinethione and S-alkylated thiazoline derivatives in excellent yields. The reaction was carried out under mild conditions using NaOH as a base and it did not require protection from air.
Process For Preparing Sulfuric Monoesters From Amino Alkanols
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Page/Page column 2-3, (2009/01/24)
Process for the preparation of sulfuric acid monoesters of aminoalkanols by reacting sulfuric acid with aminoalkanols and removing the water forming in the reaction from the reaction mixture, sulfuric acid and at least one aminoalkanol being mixed and the hot reaction mixture forming being passed with turbulent flow into a container and being quenched therein with a fluid.
Synthesis and Biological Activity of 2-Aminothiazolines and 2-Mercaptothiazolines as Octopaminergic Agonists
Hirashima, Akinori,Yoshii, Yutuka,Eto, Morifusa
, p. 2537 - 2546 (2007/10/02)
2-Aminothiazoline derivatives were synthesized by both hydrochloric acid-catalyzed cyclization of thiourea and cyclization of β-aminoalkyl hydrogen sulfate with isothiocyanate in the presence of sodium hydroxide.Substituted 2-mercaptothiazoline derivatives were prepared by alkylation or acylation of the sodium salt of 2-mercaptothiazoline, which was obtained from β-aminoalkyl hydrogen sulfate with carbon disulfide. 2-(4-Chloro-o-toluidino)-2-thiazoline (III-16) was 33percent as effective as octopamine at 100 μM in stimulating adenylate cyclase of Periplaneta americana ventral-nerve-cord homogenates.Its activity was nonadditive to the activity of octopamine.Stimulation of nerve-cord adenylate cyclase activity by III-16 was inhibited by several antagonists, including mianserin, cyproheptadine, chlorpromazine and gramine.The rank-order ability of these antagonists to block the activation by III-16 was identical to the rank-order ability of the same antagonists to block enzyme activation of octopamine.The β-adrenergic antagonist propanolol was less potent.These data suggest that III-16 is a potent and selctive agonist of octopamine-activated adenylate cyclase.Aminothiazolines which activated adenylate cyclase by 10-87percent relative to octopamine also had acaricidal activity at 300 ppm, indicating a correlation between the in vitro octopaminergic-agonist activity and in vivo acaricidal activity of aminothiazolines.
Production of aminoethyl hydrogen sulfate
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, (2008/06/13)
Aminoethyl hydrogen sulfate is produced under acidic conditions by reating ammonium bisulfate or ammonium sulfate with an ethylene compound represented by either of the formulae: STR1 where A represents C=C or C=S.
