10017-39-7Relevant articles and documents
An efficient synthesis of 2-(((9- fluorenylmethoxycarbonyl)amino)methyl)benzoic acid
Sun, Jung-Hui,Daneker, Wayne F.
, p. 4525 - 4530 (1998)
An efficient, two-step synthesis of the title compound 3 in 61% overall yield is presented. The synthesis involves hydrazine removal of the N- phthalimide protecting group of α-phthalimido-o-toluic acid (6), followed by N-Fmoc formation with (9-fluorenylm
Attachment of a hydrogen-bonding carboxylate side chain to an [FeFe]- hydrogenase model complex: Influence on the catalytic mechanism
Gao, Weiming,Sun, Junliang,Akermark, Torbjoern,Li, Mingrun,Eriksson, Lars,Sun, Licheng,Akermark, Bjoern
, p. 2537 - 2546 (2010)
Azapropanedithiolate (adt)- bridged model complexes of [FeFe]-hydrogenase bearing a carboxylic acid functionality have been designed with the aim of decreasing the potential for reduction of protons to hydrogen. Protonation of the bisphosphine complexes 4-6 has been studied by in situ IR and NMR spectroscopy, which revealed that protonation with triflic acid most likely takes place first at the N-bridge for complex 4 but at the Fe-Fe bondfor complexes 5 and 6. Using an excess of acid, the diprotonated species could also be observed, but none of the protonated species was sufficiently stable to be isolated in a pure state. Electrochemical studies have provided an insight into the catalytic mechanismsunder strongly acidic conditions, and have also shown that complexes 3 and 6 are electro-active in aqueous solution even in the absence of acid, presumably due to hydrogen bonding. Hydrogen evolution, driven by visible light, has been observed for three-component systems consisting of [Ru(bpy)3]2+ ,complex 1, 2, or 3, and ascorbic acid in CH3CN/D2O solution by on-line mass spectrometry.
Cu/Fe Catalyzed Intermolecular Oxidative Amination of Benzylic C-H Bonds
Liu, Cong,Zhang, Qi,Li, Hongbo,Guo, Shuangxi,Xiao, Bin,Deng, Wei,Liu, Lei,He, Wei
, p. 6208 - 6212 (2016/05/09)
We report a Cu/Fe co-catalyzed Ritter-type C-H activation/amination reaction that allows efficient and selective intermolecular functionalization of benzylic C-H bonds. This new reaction is featured by simple reaction conditions, readily available reagents and general substrate scope, allowing facile synthesis of biologically interesting nitrogen containing heterocycles. The Cu and Fe salts were found to play distinct roles in this cooperative catalysis. With a little help: A Ritter-type intermolecular amination of benzylic C-H bonds with acetonitrile, co-catalyzed by CuII/FeIII is reported. A wide array of biologically interesting nitrogen containing heterocycles was prepared from 2-alkyl benzoic acids and heteroaromatic carboxylic acids under operationally simple conditions. The Cu and Fe salts were found to play distinct roles in this cooperative catalysis.
