1005385-47-6

Basic information

• Product Name: 3-(4-(tert-butyl)phenyl)-1-phenylprop-2-yn-1-one
• Synonyms: 3-(4-(tert-butyl)phenyl)-1-phenylprop-2-yn-1-one
• CAS NO: 1005385-47-6
• Molecular Weight: 262.351
• Mol File: 1005385-47-6.mol
• Article Data: 39

Chemical Properties

• CAS DataBase Reference: 3-(4-(tert-butyl)phenyl)-1-phenylprop-2-yn-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-(tert-butyl)phenyl)-1-phenylprop-2-yn-1-one(1005385-47-6)
• EPA Substance Registry System: 3-(4-(tert-butyl)phenyl)-1-phenylprop-2-yn-1-one(1005385-47-6)

Safety Data

• Hazardous Substances Data: 1005385-47-6(Hazardous Substances Data)

Upstream product

• 772-38-3 4-tert-Butylphenylacetylene 
• 100-52-7 benzaldehyde 
• 201230-82-2 carbon monoxide 
• 59-88-1 phenylhydrazine hydrochloride 
• 591-50-4 iodobenzene 
• 124-38-9 carbon dioxide 
• 35779-04-5 1-tert-butyl-4-iodobenzene 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 
• 220006-53-1 3-(4-(tert-butyl)phenyl)propiolic acid 
• 65-85-0 benzoic acid 
• 98-86-2 acetophenone 
• 611-73-4 Benzoylformic acid 
• 939-97-9 4-tert-Butylbenzaldehyde 
• 64-18-6 formic acid 

Downstream Products

• 1324007-20-6 C₃₁H₂₇F₃N₂O₂ 
• 883018-08-4 2-(4-(tert-butyl)phenyl)-5-methylbenzo[d]oxazole 
• 1350516-24-3 4-(4-tert-butylphenyl)-7-(trifluoromethyl)-2-phenyl-9H-pyrido-[2,3-b]indole 
• 1350516-21-0 4-(4-tert-butylphenyl)-6-methyl-2-phenyl-9H-pyrido[2,3-b]indole 
• 1042682-69-8 2-[1-(4-tert-butylphenyl)-2-fluoro-2-(phenylsulfonyl)ethylidene]-1,3-diphenylpropane-1,3-dione 
• 1042682-61-0 (E)-3-(4-tert-butylphenyl)-4-fluoro-1-phenyl-4,4-bis(phenylsulfonyl)but-2-en-1-one 

Relevant articles and documents

A highly efficient nano-sized Cu2O/SiO2 egg-shell catalyst for C-C coupling reactions

Mesoporous SiO2-supported Cu2O nanoparticles as an egg-shell type catalyst were prepared by impregnation method. The obtained Cu2O/SiO2 egg-shell nanocatalyst had a large surface area and narrow pore size distri

Palladium-catalyzed Sonogashira cross-coupling of organic tellurides with alkynes

Alkyl aryl tellurides and a tellurol ester were used as coupling partners in Pd(0)-catalyzed Sonogashira reactions. Microwave-assisted reactions of alkyl aryl tellurides with alkynes in the presence of CuI and catalytic amounts of Pd(PPh3)4 produced alkynyl arenes. Similarly, a tellurol ester on reaction with alkynes afforded alkynyl phenyl ketones in the presence of CuI and a catalytic amount of Pd(PPh3)4 at room temperature.

A facile and efficient method for the synthesis of alkynone by carbonylative Sonogashira coupling using CHCl3 as the CO source

A facile and efficient method for the synthesis of alkynones by a Pd-catalyzed carbonylative Sonogashira coupling reaction starting from aryl iodide, terminal alkyne and chloroform (CHCl3) as the CO source is described. This procedure proves th

Palladium-catalyzed carbonylative Sonogashira coupling of aryl diazonium salts with formic acid as the CO source: The effect of 1,3-butadiene

An efficient carbonylative cross-coupling of aryl diazonium salts with terminal alkynes using formic acid as the CO source has been developed. Various useful alkynones were produced in moderate to good yields. Notably, 1,3-butadiene was found to play a crucial role in this transformation.

Merging " Anti-Baldwin" 3- Exo-Dig Cyclization with 1,2-Alkynyl Migration for Radical Alkylalkynylation of Unactivated Olefins

A new combination of "anti-Baldwin" 3-exo-dig cyclization with 1,2-alkynyl migration of 1,4-enynes with simple cycloalkanes was established, enabling C-C breaking and reconstruction to access a wide range of α-alkynyl ketones with generally good yields by

Synthesis of 1-Cyano-3-acylnaphthalenes via Formal [4+2] Benzannulation of 2-(2-Alkynylphenyl)acetonitriles and Alkynones

Effective transition-metal-free formal [4+2] benzannulation for the preparation of 1-cyano-3-acylnaphthalenes from 2-(2-alkynylphenyl)acetonitriles and alkynones through sequential C-C bond coupling has been developed. This protocol is characterized by mi

One-Pot Palladium-Catalyzed Carbonylative Sonogashira Coupling using Carbon Dioxide as Carbonyl Source

Carbonylation coupling reaction has emerged as a powerful and versatile strategy for the construction of carbonyl-containing compounds in modern synthetic chemistry over the past years. Carbon dioxide, a renewable one carbon molecule, has become one of the most attractive and promising alternative carbonyl sources due to its highly abundance, nontoxicity and stability in comparison with CO in recent years. However, in most cases, a two-chamber technique was generally necessary to allow the CO-producing and CO-consuming processes to perform successfully because of the complexities and incompatibility of reaction conditions, when carbon dioxide was utilized as carbonyl source. Herein, a practical one-pot protocol using carbon dioxide as the carbonyl source for the palladium-catalyzed carbonylative Sonogashira coupling has been established, providing an expedient and practical route to a wide range of functionalized alkynones and indoxyls under mild reaction conditions. By finding a suitable catalytic system, the method allowed the CO-generating and CO-consuming processes to proceed in one pot, wherein carbon monoxide was generated in situ from the reduction of carbon dioxide in the absence of any fluoride reagents. Simple and safe operation, readily available substrates, good functional group tolerance and mild reaction conditions are the features of the method.

Base-Promoted Synthesis of Polysubstituted 4-Aminoquinolines from Ynones and 2-Aminobenzonitriles under Transition-Metal-Free Conditions

A transition-metal-free and base-promoted one-pot reaction of ynones with 2-aminobenzonitriles is described. The reaction was initiated through sequential aza-Michael addition/intramolecular annulation to afford various multisubstituted 4-aminoquinolines