1014645-87-4

Basic information

• Product Name: Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1)
• Synonyms: Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1);Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1)/4-(1-Aminocyclopropyl)benzoic acid methyl ester hydrochloride;Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride;Methyl 4-(1-aminocyclopropyl)
• CAS NO: 1014645-87-4
• Molecular Formula: C₁₁H₁₃NO₂*ClH
• Molecular Weight: 227.68736
• Mol File: 1014645-87-4.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1)(1014645-87-4)
• EPA Substance Registry System: Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1)(1014645-87-4)

Safety Data

• Hazardous Substances Data: 1014645-87-4(Hazardous Substances Data)

Usage

General Description

Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1) is a chemical compound that consists of benzoic acid, methyl ester, and hydrochloride in a 1:1 ratio. It is a white, crystalline powder that is commonly used in pharmaceutical and organic synthesis applications. Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1) has potential pharmaceutical properties and has been studied for its potential use as an antifungal agent. It is also known to have antibacterial and antiviral properties. Additionally, this chemical may have potential applications in the treatment of various diseases and disorders. Overall, Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1) is a versatile compound with potential uses in medicine and pharmaceuticals.

Upstream product

• 1338243-88-1 methyl 4-(1-((tert-butoxycarbonyl)amino)cyclopropyl)benzoate 
• 1129-35-7 4-cyanobenzoic acid methyl ester 
• 360773-84-8 tert-butyl [1-(4-bromophenyl)-cyclopropyl]-carbamate 
• 345965-52-8 1-(4-bromophenyl)cyclopropanecarboxylic acid 
• 1014743-82-8 4-(1-aminocyclopropyl)benzoic acid 
• 67-56-1 methanol 
• 1014645-83-0 4-(1-aminocyclopropyl)benzoic acid hydrochloride 
• 1006037-03-1 4-(1-aminocyclopropyl)-benzoic acid methyl ester 

Downstream Products

• 1006037-11-1 methyl 4-{1-[({2,5-dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]cyclopropyl}benzoate 
• 1369490-23-2 C₂₃H₁₈Cl₂F₃N₃O₄ 
• 1369489-88-2 ER-888363-00 
• 1380755-18-9 methyl 4-(1-(2-(3-((3-fluorophenyl)amino)azetidin-1-yl)-5-(trifluoromethyl)nicotinamido)cyclopropyl)benzoate 
• 1380753-67-2 methyl 4-(1-(2,5-dichloronicotinamido)cyclopropyl)benzoate 
• 1380750-84-4 4-(1-(5-chloro-2-(3-(3-fluorobenzoyl)azetidin-1-yl)nicotinamido)cyclopropyl)benzoic acid 
• 1380750-88-8 4-(1-(5-chloro-2-(3-((3-fluorophenyl)(methoxyimino)methyl)azetidin-1-yl)nicotinamido)cyclopropyl)benzoic acid 
• 1380751-13-2 4-(1-(5-chloro-2-(3-((4-fluoro-2-methylphenyl)amino)azetidin-1-yl)nicotinamido)cyclopropyl)benzoic acid 
• 1380754-68-6 methyl 4-(1-(5-chloro-2-(3-(3-(piperazin-1-yl)phenoxy)azetidin-1-yl)nicotinamido)cyclopropyl)benzoate 
• 1380754-78-8 methyl 4-(1-(5-chloro-2-(3-(3-fluorobenzoyl)azetidin-1-yl)nicotinamido)cyclopropyl)benzoate 
• 1380754-92-6 methyl 4-(1-(5-chloro-2-(3-((4-fluoro-2-methylphenyl)amino)azetidin-1-yl)nicotinamido)cyclopropyl)benzoate 
• 1380750-15-1 4-(1-(5-chloro-2-(2-phenylpyrrolidin-1-yl)nicotinamido)cyclopropyl)benzoic acid 
• 1380754-44-8 methyl 4-(1-(5-chloro-2-(2-phenylpyrrolidin-1-yl)nicotinamido)cyclopropyl)benzoate 
• 1380750-32-2 4-(1-(2-(2-benzylpyrrolidin-1-yl)-5-chloronicotinamido)cyclopropyl)benzoic acid 

Relevant articles and documents

NOVEL INDOLE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)

The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.

PHENOXYETHYL PIPERIDINE COMPOUNDS

The present invention provides a compound of the Formula II: Formula II wherein X is: R1 is H, -CN, or F; R2 is H or methyl; R3 is H; and R4 is H, methyl, or ethyl; or R3 and R4 joined toge

PYRIDINE AMIDE DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS

The invention relates pyridine amide derivative of Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are independently hydrogen, linear o branched (C1-C3)alkyl or joined together they form a cyclopropyl ring; R is independently selected from the group consisting of halogens and trifluoromethyl and p is 1, 2 or 3; A is C or N; E is a group of formula (B) or (C), wherein B is C(O)OH, C(O)O(C1-C3)alkyl, and C is selected from the group consisting of formula (I) m is 1,2 or 3, n is 0 or 1, W is -O-, -O(C1-C3 alkyl)-; -(C1-C3 alkyl)O-; -C(O)-; -C(=N-O(C1-C3 alkyl))-; -NH- or -NH(C1-C3alkyl)-; Ar is phenyl, optionally substituted with one or more substituents selected from the group consisting of halogen, trifluoromethyl, trifluoromethoxy, methyl, -NH(C1-C3alkyl)-; -N(C1-C3alkyl)(C1-C3alkyl)-, a from 5 to 7 membered heterocyclic ring containing one nitrogen atom which is convalently bonded to Ar and optionally containing one or two heteroatoms selected from N, O and S; and a 5- or 6-membered heteroaromatic ring containing 1 to 3 heteroatoms selected from S, O e N, such heteroaromatic ring being substituted with one or two substituents selected from the group consisting of (C1-C3)alkyl, (C3-C5)cycloalkyloxy, (C1-C3)alkylcarbonyl. The compounds of the invention could be used for manufacturing a medicament for the treatment of pathologies which require the use of an antagonist of the EP4 receptor, such as the treatment of acute and chronic pain, inflammatory pain, osteoarthritis, inflammation-associated disorder as arthritis, rheumatoid artrhritis, cancer, endometriosis and migraine.