87386-07-0

Basic information

• Product Name: Glycine, N-(phenylthioxomethyl)-, ethyl ester
• CAS NO: 87386-07-0
• Molecular Formula: C11H13NO2S
• Molecular Weight: 223.296
• Mol File: 87386-07-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Glycine, N-(phenylthioxomethyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Glycine, N-(phenylthioxomethyl)-, ethyl ester(87386-07-0)
• EPA Substance Registry System: Glycine, N-(phenylthioxomethyl)-, ethyl ester(87386-07-0)

Safety Data

• Hazardous Substances Data: 87386-07-0(Hazardous Substances Data)

Upstream product

• 98-91-9 thiobenzoic acid 
• 637-81-0 ethyl-2-azidoacetate 
• 495-69-2 Hippuric Acid 
• 98-88-4 benzoyl chloride 
• 623-33-6 glycine ethyl ester hydrochloride 
• 942-91-6 Carboxymethyl dithiobenzoate 

Downstream Products

• 16446-30-3 4-benzylidene-2-phenyl-4H-thiazol-5-one 
• 16446-29-0 2-phenyl-3-thiazolin-5-one 
• 16446-03-0 4-[2-(5'-chloro-8'-methoxy-3',4'-dihydro-2'H-spiro[[1,3]dioxolane-2,1'-naphthalen]-3'-yl)-ethylidene]-2-phenyl-4H-thiazol-5-one 
• 161198-41-0 ethyl 2,5-diphenyl-4-thiazolecarboxylate 
• 93729-29-4 ethyl 2,5-diphenyloxazole-4-carboxylate 
• 15926-46-2 diethyl 2-phenyl-4,5-oxazoledicarboxylate 
• 82507-66-2 1,4,5-trihydro-3-pheny<1,2,4>triazin-6(2H)-one 
• 103112-01-2 N-glycine ethyl ester 
• 2584-64-7 N-(thiobenzoyl)glycine 

Relevant articles and documents

Chemoselectivity in coupling of azides with thioacids in solution-phase and solvent-free conditions

Solvent-free rapid coupling of monothiocarboxylic acid with azide affords carboxamide chemoselectively. Triphenyl phosphine included as an additive influences the chemoselectivity, yielding carboxamide and thioamide. Similar variation in the chemoselectivity is observed in the absence and presence of triphenyl phosphine in solution-phase methodology. Rapidity and ecofriendliness of the solvent-free approach to yield the products in just 15min is noteworthy compared to the solution-phase protocol, which has a long reaction time (1-3 days).

Synthesis of oxazoles and thiazoles using thioimidates

Several oxazoles and thiazoles were synthesized easily by the reaction of N-(methylthioalkylidene)glycine ethyl ester with diethyl oxalate, acid halides, and thionesters in the presence of base.