10364-35-9

Upstream product

• 17206-91-6 1,4-Diacetoxybicyclo<2.2.2>oct-2-ene 
• 17206-90-5 1,4-Diacetoxybicyclo<2.2.2>octane-2,3-dicarboxylic Acid 
• 4982-20-1 1,4-dimethylidenecyclohexane 
• 64-19-7 acetic acid 
• 108-24-7 acetic anhydride 
• 141-78-6 ethyl acetate 

Downstream Products

• 1194-44-1 1,4-dihydroxybicyclo[2.2.2]octane 
• 1123-39-3 1,4-Dichloro-bicyclo<2.2.2>octane 
• 10364-04-2 bicyclo[2.2.2]octane-1,4-dibromide 
• 10364-05-3 1,4-diiodobicyclo<2.2.2>octane 
• 54774-94-6 4-acetoxybicyclo<2.2.2>octan-1-ol 
• 280-33-1 bicyclo[2,2,2]octane 
• 1459-96-7 dimethyl bicyclo[2.2.2]octane-1,4-dicarboxylate 
• 826-45-9 Bicyclo<2.2.2>octane-1,4-dimethanol 
• 94994-15-7 4-hydroxymethyl-bicyclo[2.2.2]octane-1-carboxylic acid methyl ester 
• 711-02-4 1,4-bicyclo[2.2.2]octanedicarboxylic acid 

Relevant academic research and scientific papers

SYNTHESIS OF BICYCLO[2.2.2]OCTANE DERIVATIVES

Provided is a process for the preparation of certain 1,4-bicyclo[2.2.2]octane derivatives. The new synthetic procedure involves treating 1,4-dimethylene cyclohexane with an oxidizing agent in the presence of a transition metal catalyst to afford an oxo-substituted bicyclo[2.2.2]octane species. This intermediate structure can then be further derivatized. The processes of this disclosure thus affords a novel and simplified means for the commercial production of a wide variety of bicyclo[2.2.2]octane derivatives.

SYNTHESIS OF BICYCLO(2.2.2)OCTANES

Provided is a process for the preparation of certain 1,4- bicyclo[2.2.2]octane derivatives. The new synthetic procedure involves treating 1,4-dimethylene cyclohexane with an oxidizing agent in the presence of a transition metal catalyst comprising a palla

SYNTHESIS OF BRIDGEHEAD BICYCLOOCTANOLS

The paper describes syntheses of bicyclooctan-1-ol, its 4-methyl and 4-phenyl derivatives, and bicyclooctane-1,4-diol.