54774-94-6Relevant articles and documents
228. Polar Effects. Part 14. Inductive Charge Dispersal in Bicyclooct-1-yl Cations
Bielmann, Rolf,Grob, Cyril A.,Kuery, Dieter,Yao, Guo Wei
, p. 2158 - 2164 (1985)
The rate constants (log k) for solvolysis of 2-, 3-, and 4-substituted bicyclooctyl p-nitrobenzenesulfonates 10, 11, and 12, respectively, correlate linearly with the corresponding inductive substituent constants ?qI.The formation of the ion pairs 9 is, therefore, controlled by the I effect of the neighboring substituents.It follows from the corresponding reaction constants ρI of -1.54, -1.12, and -1.22 that inductivity is highest at the positions α to C(1).It is lower and practically equal at the β- and γ-positions.Therefore, charge dispersal is similar to that previously observed in the quinuclidinium ion 7.
SYNTHESIS OF BICYCLO(2.2.2)OCTANES
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Paragraph 0063, (2018/05/15)
Provided is a process for the preparation of certain 1,4- bicyclo[2.2.2]octane derivatives. The new synthetic procedure involves treating 1,4-dimethylene cyclohexane with an oxidizing agent in the presence of a transition metal catalyst comprising a palla