1036715-60-2

Basic information

• Product Name: Methyl 4-acetyl-2-Methylbenzoate
• Synonyms: Methyl 4-acetyl-2-Methylbenzoate
• CAS NO: 1036715-60-2
• Molecular Formula: C₁₁H₁₂O₃
• Molecular Weight: 192.21118
• EINECS: -0
• Mol File: 1036715-60-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Methyl 4-acetyl-2-Methylbenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-acetyl-2-Methylbenzoate(1036715-60-2)
• EPA Substance Registry System: Methyl 4-acetyl-2-Methylbenzoate(1036715-60-2)

Safety Data

• Hazardous Substances Data: 1036715-60-2(Hazardous Substances Data)

Usage

Uses

Used in Flavor and Fragrance Industry:
Methyl 4-acetyl-2-Methylbenzoate is used as a flavoring agent and fragrance ingredient for its distinctive aromatic properties, enhancing the sensory experience of various products.
Used in Pharmaceutical Synthesis:
As an intermediate in the synthesis of pharmaceuticals, Methyl 4-acetyl-2-Methylbenzoate plays a crucial role in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Cosmetics and Personal Care Products:
Methyl 4-acetyl-2-Methylbenzoate is utilized in the production of cosmetics and personal care products, where it may serve as a scent component or contribute to the formulation's overall effectiveness.
Used in Industrial Processes:
Methyl 4-acetyl-2-Methylbenzoate is also employed in various industrial processes, where its chemical properties can be harnessed for specific applications, such as in the manufacturing of certain types of plastics or other materials.

Upstream product

• 67-56-1 methanol 
• 3637-01-2 3,4-dimethylacetophenone 
• 369-32-4 1-(4-fluoro-3-methylphenyl)ethanone 
• 95-52-3 2-Fluorotoluene 
• 99548-55-7 4-bromo-2-methyl-benzoic acid methyl ester 
• 201230-82-2 carbon monoxide 
• 37074-40-1 1-(4-bromo-3-methylphenyl)ethan-1-one 
• 51930-77-9 1-(4-bromo-3-methylphenyl)ethan-1-ol 
• 78775-11-8 3-methyl-4-bromobenzaldehyde 
• 55860-35-0 4-acetyl-2-methyl benzoic acid 

Downstream Products

• 1391709-79-7 C₁₈H₁₅FO₃ 
• 1391709-90-2 4-(5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-3-yl)-2-methylbenzohydrazide 
• 1391709-74-2 C₁₈H₁₅ClO₃ 
• 1391709-78-6 C₁₈H₁₅ClO₃ 
• 1391709-89-9 4-(5-(2-chlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl)-2-methylbenzohydrazide 
• 1391709-70-8 C₁₈H₁₅NO₅ 
• 1391709-75-3 C₁₈H₁₅NO₅ 
• 1391709-76-4 C₁₈H₁₆O₃ 
• 1391709-87-7 4-(4,5-dihydro-5-phenyl-1H-pyrazol-3-yl)-2-methylbenzohydrazide 
• 1391709-71-9 C₁₈H₁₆O₄ 
• 1391709-77-5 C₁₉H₁₈O₄ 
• 1391709-88-8 4-(4,5-dihydro-5-(4-methoxyphenyl)-1H-pyrazol-3-yl)-2-methylbenzohydrazide 
• 1391709-69-5 C₁₈H₁₆O₄ 
• 1391709-73-1 C₁₉H₁₈O₅ 

Relevant articles and documents

Catalytic Enantioselective Direct Aldol Addition of Aryl Ketones to α-Fluorinated Ketones

The catalytic enantioselective synthesis of α-fluorinated chiral tertiary alcohols from (hetero)aryl methyl ketones is described. The use of a bifunctional iminophosphorane (BIMP) superbase was found to facilitate direct aldol addition by providing the strong Br?nsted basicity required for rapid aryl enolate formation. The new synthetic protocol is easy to perform and tolerates a broad range of functionalities and heterocycles with high enantioselectivity (up to >99:1 e.r.). Multi-gram scalability has been demonstrated along with catalyst recovery and recycling. 1H NMR studies identified a 1400-fold rate enhancement under BIMP catalysis, compared to the prior state-of-the-art catalytic system. The utility of the aldol products has been highlighted with the synthesis of various enantioenriched building blocks and heterocycles, including 1,3-aminoalcohol, 1,3-diol, oxetane, and isoxazoline derivatives.

Method for synthesizing methyl 2-methyl-4-acetyl benzoate

The invention provides a method for synthesizing methyl 2-methyl-4-acetyl benzoate. The method comprises the following steps: (1) adding an acylating reagent to a solution with dissolved 2-fluorotoluene, and carrying out an acylation reaction so as to obtain 4-fluoro-3-methylacetophenone; (2) dissolving the obtained 4-fluoro-3-methylacetophenone, adding a cyanation reagent, and carrying out a cyanation reaction so as to obtain 3-methyl-4-cyanoacetophenone; (3) adding acid to the 3-methyl-4-cyanoacetophenone, and carrying out a hydrolysis reaction so as to obtain 2-methyl-4-acetylbenzoic acid;and (4) adding methanol to the 2-methyl-4-acetylbenzoic acid, and carrying out an esterification reaction so as to obtain methyl 2-methyl-4-acetyl benzoate. The method has simple operation, a high reaction yield, easily purchasable reagents and instruments and low cost, and is feasible in specific practical application.

Modulators of methyl modifying enzymes, compositions and uses thereof

Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.

SUBSTITUTED BENZENE AND 6,5-FUSED BICYCLIC HETEROARYL COMPOUNDS

The present invention relates to substituted benzene compounds and bicyclic heteroaryl compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein

Synthesis and antimicrobial screening of some novel pyrazoline derivatives

New series of methyl-4-(4,5-dihydro-5-[(Z)phenyl]-1H-pyrazol-3-yl)-2- methylbenzohydrazide were synthesized by cyclisization of chalcones, methyl 4-((E)-3-((Z)phenyl)acryloyl)-2-methylbenzoate with hydrazine hydrate in presence of basic media. The chalcon

Selective oxidation of acetophenones bearing various functional groups to benzoic acid derivatives with molecular oxygen

Acetophenones substituted by alkyl, alkoxy, acetoxy, and halogen groups were selectively oxidized with molecular oxygen to the corresponding benzoic acids by using the N,N',N"-trihydroxyisocyanuric acid (THICA)/cobalt(II) acetate [Co(OAc)2] and THICA/Co(OAc)2/manganese(II) acetate.