1081-48-7

Basic information

• Product Name: 1-phenyl-2-(pyridin-3-yl)ethanone
• CAS NO: 1081-48-7
• Molecular Formula: C₁₃H₁₁NO
• Molecular Weight: 197.2325
• Mol File: 1081-48-7.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 348.7°C at 760 mmHg
• Flash Point: 172.6°C
• Density: 1.127g/cm³
• Vapor Pressure: 4.93E-05mmHg at 25°C
• Refractive Index: 1.588
• CAS DataBase Reference: 1-phenyl-2-(pyridin-3-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-2-(pyridin-3-yl)ethanone(1081-48-7)
• EPA Substance Registry System: 1-phenyl-2-(pyridin-3-yl)ethanone(1081-48-7)

Safety Data

• Hazardous Substances Data: 1081-48-7(Hazardous Substances Data)

Usage

Physical state

Yellow liquid

Odor

Sweet, floral

Usage

Intermediate in the synthesis of pharmaceuticals and other organic compounds

Chemical class

Ketone (contains a carbonyl group bonded to two carbon atoms)

Substitution

Phenyl group and pyridine group

Value in research and industry

Ability to undergo various chemical reactions, making it a valuable building block in organic synthesis

Safety precautions

Handle with care, as it can be hazardous if not properly handled and stored.

Upstream product

• 98-88-4 benzoyl chloride 
• 108-99-6 3-Methylpyridine 
• 6919-61-5 N-methoxy-N-methylbenzamide 
• 1696-17-9 N,N-diethylbenzamide 
• 1120-90-7 3-iodopyridine 
• 98-86-2 acetophenone 
• 694-59-7 pyridine N-oxide 
• 2216-94-6 phenylpropynoic acid ethyl ester 
• 613-90-1 benzoyl cyanide 
• 31729-70-1 bis(iodozinc)methane 
• 626-55-1 3-Bromopyridine 
• 626-60-8 3-Chloropyridine 
• 308103-40-4 (2-acetylphenyl)boronic acid 
• 1233943-56-0 ethyl 3-oxo-3-phenyl-2-(pyridin-3-yl)propanoate 

Downstream Products

• 1233943-57-1 2-(hydroxyimino)-1-phenyl-2-(pyridin-3-yl)ethanone 
• 6312-10-3 1-phenyl-2-(pyridin-3-yl)ethan-1-ol 
• 62144-14-3 1,2-diphenyl-2-(pyridin-3-yl)ethan-1-one 
• 1283118-01-3 4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-6-phenyl-5-(pyridin-3-yl)-3,4-dihydropyrimidin-2(1H)-one 
• 70827-30-4 5-phenyl-6-(3-pyridyl)-2,3-dihydroimidazo<2,1-b>thiazol 
• 74212-39-8 6-phenyl-4-propylpyridazine 
• 23826-56-4 1-phenyl-2-(pyridin-3-yl)ethane-1,2-dione 
• 6312-09-0 3-(2-phenylethyl)pyridine 
• 6632-77-5 3-(2-hydroxy-2,2-diphenylethyl)pyridine 
• 99466-49-6 2-Bromo-1-phenyl-2-(pyridin-3-yl)ethanone Hydrobromide 
• 1620-43-5 1-methyl-3-phenacylpyridinium iodide 
• 138625-38-4 α-Phenyl-α-trichlormethyl-3-pyridinethanol 

Relevant articles and documents

Asymmetric transfer hydrogenation of heterocycle-containing acetophenone derivatives using N-functionalised [(benzene)Ru(II)(TsDPEN)] complexes

The application of enantiomerically-pure ruthenium(II) catalysts containing N - functionalised TsDPEN ligand to the asymmetric transfer hydrogenation of 15 examples of α-heterocyclic acetophenone derivatives is reported. Products of up to 99% ee were formed.

Palladium-Catalyzed Direct α-C(sp3) Heteroarylation of Ketones under Microwave Irradiation

Heteroaryl compounds are valuable building blocks in medicinal chemistry and chemical industry. A palladium-catalyzed direct α-C(sp3) heteroarylation of ketones under microwave irradiation is developed and reported in this study. Under optimized condition

NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME

The present invention provides novel transition-metal precatalysts that are useful in preparing active coupling catalysts. In certain embodiments, the precatalysts of the invention are air-stable and moisture-stable. The present invention further provides methods of making and using the precatalysts of the invention.