763-69-9

Basic information

• Product Name: Ethyl-3-ethoxypropanoate
• Synonyms: 4-03-00-00697 (Beilstein Handbook Reference);AI3-03254;BRN 1751976;Ethoxypropionic acid, ethyl ester;Ethyl beta-ethoxypropionate
• CAS NO: 763-69-9
• Molecular Formula: C₇H₁₄O₃
• Molecular Weight: 146.18426
• EINECS: 212-112-9
• Mol File: 763-69-9.mol
• Article Data: 26

Chemical Properties

• Melting Point: -75℃
• Boiling Point: 166.2 ºC at 760 mmHg
• Flash Point: 52.2 ºC
• Appearance: clear, colorless liquid
• Density: 0.949 g/cm³
• Vapor Pressure: 1.8mmHg at 25°C
• Refractive Index: 1.408
• Water Solubility: 1.6 g/100 mL (20℃)
• CAS DataBase Reference: Ethyl-3-ethoxypropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl-3-ethoxypropanoate(763-69-9)
• EPA Substance Registry System: Ethyl-3-ethoxypropanoate(763-69-9)

Safety Data

• Hazard Codes: Xi:Irritant;; <
• Statements: R10:; R19:; R36:; R50:
• Safety Statements: S25:
• Hazardous Substances Data: 763-69-9(Hazardous Substances Data)

Usage

General Description

Ethyl-3-ethoxypropanoate is a chemical compound classified under the esters family. It is known by other names, such as ethyl 3-ethoxypropionate or EEP, and its molecular formula is C7H14O3. This colorless liquid has a pleasant odor and is primarily used as a solvent in various industrial applications because of its good solvency characteristics. It is prominently used in coatings, printing inks, and adhesives. It’s also used in the manufacture of cosmetics and personal care products. Being flammable, it needs careful handling and storage. It's considered relatively safe; however, overexposure can cause irritation to the skin, eyes, and respiratory tract.

InChI:InChI=1/C7H14O3/c1-3-9-6-5-7(8)10-4-2/h3-6H2,1-2H3

Synthetic route

ethanol (64-17-5) + ethyl acrylate (140-88-5) → ethyl 3-ethoxypropionate (763-69-9)

Conditions	Yield
With quaternary ammonium salt anion exchange resin In water at 30℃; for 4h; Temperature; Inert atmosphere;	98%
With triethylamine at 20℃; for 8h; Reagent/catalyst; Large scale;	98%
With aluminum oxide; potassium fluoride In acetonitrile at 20℃; for 18h; Michael addition reaction;	90%

sodium ethanolate (141-52-6) + ethyl acrylate (140-88-5) → ethyl 3-ethoxypropionate (763-69-9)

Conditions	Yield
In ethanol at 40℃; for 3h; Inert atmosphere;	97.6%

formaldehyde diethyl acetal (462-95-3) → ethyl 3-ethoxypropionate (763-69-9)

Conditions	Yield
With sulfuric acid; acetic anhydride	92%

potassium ethoxide (917-58-8) + ethyl acrylate (140-88-5) → ethyl 3-ethoxypropionate (763-69-9)

Conditions	Yield
With 10H-phenothiazine In methanol at 40 - 100℃; for 2h;	86%

ethanol (64-17-5) + 2-methylenebutyric acid (3586-58-1) → ethyl 3-ethoxypropionate (763-69-9)

Conditions	Yield
With 10H-phenothiazine; potassium ethoxide at 40 - 80℃; for 2h; Reagent/catalyst;	86%

ethyl 2-bromo-3-ethoxypropanoate (78097-85-5) → ethyl 3-ethoxypropionate (763-69-9)

Conditions	Yield
With sodium diethyl phosphate for 5h; Ambient temperature;	72%

sodium ethanolate (141-52-6) + hexyl-methyl-ketone (111-13-7) + ethyl acrylate (140-88-5) → ethyl 3-ethoxypropionate (763-69-9) + 4-pentyl-1,3-cyclohexanedione (63649-30-9)

Conditions	Yield
In tetrahydrofuran at 20℃; for 1h;	A 30% B 58%

acetone (67-64-1) + ethyl acrylate (140-88-5) → ethyl 3-ethoxypropionate (763-69-9) + ethyl 3-(2,4-dioxocyclohexyl)propanoate (1335209-87-4) + 1,3-cylohexanedione (504-02-9)

Conditions	Yield
With sodium hydride In toluene at -10 - 20℃; for 2h; Michael-Claisen cyclization; Inert atmosphere; regioselective reaction;	A 8% B 54% C 3%
With sodium hydride at -10 - 20℃; for 0.0833333h; Michael-Claisen cyclization; Inert atmosphere; neat (no solvent); regioselective reaction;	A 6% B 39% C 9%

2-(2'-Ethoxycarbonylethyl)-saccharin (83747-24-4) + sodium ethanolate (141-52-6) → ethyl 3-ethoxypropionate (763-69-9) + saccharin (81-07-2)

Conditions	Yield
In ethanol Heating;	A n/a B 50%

β-Propiolactone (57-57-8) + ethanol (64-17-5) → ethyl 3-ethoxypropionate (763-69-9)

Conditions	Yield
With sulfuric acid
(i), (ii) (esterification); Multistep reaction;

Ethyl 3-bromopropionate (539-74-2) + sodium ethanolate (141-52-6) → ethyl 3-ethoxypropionate (763-69-9)

ethyl 3-iodopropanoate (6414-69-3) + sodium ethanolate (141-52-6) → ethyl 3-ethoxypropionate (763-69-9)

Conditions	Yield
With diethyl ether

sodium ethanolate (141-52-6) + ethyl 3-chloropropanoate (623-71-2) → ethyl 3-ethoxypropionate (763-69-9)

ethanol (64-17-5) + 3-(ethoxy)propionitrile (2141-62-0) → ethyl 3-ethoxypropionate (763-69-9)

Conditions	Yield
With sulfuric acid
With sulfuric acid

formaldehyde diethyl acetal (462-95-3) + bromo(2-ethoxy-2-oxoethyl)zinc (5764-82-9) → ethyl 3-ethoxypropionate (763-69-9)

Conditions	Yield
With acetyl chloride

ethanol (64-17-5) + 1,1,1-trichloro-3-ethoxy-propane (89181-45-3) → ethyl 3-ethoxypropionate (763-69-9)

Conditions	Yield
With potassium hydroxide

ethanol (64-17-5) + 3-Bromo-propionimidic acid ethyl ester; hydrochloride → ethyl 3-ethoxypropionate (763-69-9)

3-phenoxypropionic acid ethyl ester (22409-91-2) + sodium ethanolate (141-52-6) → ethyl 3-ethoxypropionate (763-69-9)

Conditions	Yield
In ethanol

ethyl acrylate (140-88-5) → ethyl 3-ethoxypropionate (763-69-9)

Conditions	Yield
With tetraethylammoniumcyanide In acetonitrile

methyl vinyl ketone (78-94-4) + ethyl acrylate (140-88-5) → ethyl 3-ethoxypropionate (763-69-9)

Conditions	Yield
With sodium hydroxide; cetyltrimethylammonim bromide In dichloromethane	70 % Chromat.

ethanol (64-17-5) + ethyl acrylate (140-88-5) → 4-oxopimelate (6317-49-3) + ethyl 3-ethoxypropionate (763-69-9) + Ethyl propionate (105-37-3) + 4-Ethoxycarbonyl-4-methyl-5-oxo-octanedioic acid diethyl ester

Conditions	Yield
With potassium tetracarbonylhydridoferrate at 70℃; for 30h;	A 3 mmol B 3 mmol C 27 mmol D n/a
With potassium tetracarbonylhydridoferrate at 70℃; for 30h;	A n/a B 3 mmol C 27 mmol D 3 mmol

ethanol (64-17-5) + ethyl acrylate (140-88-5) → 4-oxopimelate (6317-49-3) + ethyl 3-ethoxypropionate (763-69-9) + Ethyl propionate (105-37-3) + Diethyl methylmalonate (609-08-5)

Conditions	Yield
With potassium tetracarbonylhydridoferrate at 70℃; for 30h; Product distribution; time, atmosphere;

sodium ethanolate (141-52-6) + ethyl acrylate (140-88-5) → ethyl 3-ethoxypropionate (763-69-9) + α-methylene-glutaric acid diethyl ester

Conditions	Yield
at 80 - 100℃; und Behandeln mit kalter verd.Saeure;

ethyl nitrite (109-95-5) + 3-amino-propionic acid-hydrochloride → ethyl 3-ethoxypropionate (763-69-9)

Conditions	Yield
With ethanol at 95 - 105℃; unter Druck;

ethanol (64-17-5) + ethyl acrylate (140-88-5) → ethyl 3-ethoxyacrylate (1001-26-9) + ethyl 3-ethoxypropionate (763-69-9) + ethyl 3,3-diethoxypropanoate (10601-80-6)

Conditions	Yield
With carbon dioxide; oxygen; copper(l) chloride; dichloro bis(acetonitrile) palladium(II) at 40℃; under 97507.8 Torr; for 12h;	A 6.0 % Chromat. B 5.6 % Chromat. C 75.8 % Chromat.

ethanol (64-17-5) + 3-hydroxypropionic acid (503-66-2) → ethyl 3-ethoxypropionate (763-69-9)

Conditions	Yield
sodium hydroxide In water at 220℃; under 2585.81 Torr; for 1.6h; Product distribution / selectivity;	5 - 50 %Chromat.
calcium hydroxide In water at 220℃; under 2585.81 Torr; for 1.6h; Product distribution / selectivity;	5 - 50 %Chromat.
magnesium hydroxide In water at 220℃; under 2585.81 Torr; for 1.6h; Product distribution / selectivity;	5 - 50 %Chromat.

3-bromo-1,1,1-trichloro-3-ethoxy-propane (89180-39-2) → ethyl 3-ethoxypropionate (763-69-9)

Conditions	Yield
Multi-step reaction with 2 steps 1: LiAlH4 / diethyl ether 2: aq. KOH View Scheme

ethyl 3-ethoxypropionate (763-69-9) + formic acid ethyl ester (109-94-4) → trans-2-Ethoxymethylen-3-ethoxy-propionsaeure-ethylester

Conditions	Yield
Stage #1: ethyl 3-ethoxypropionate; formic acid ethyl ester With sodium ethanolate In tetrahydrofuran at 20℃; for 1h; Stage #2: With dimethyl sulfate In tetrahydrofuran at 50℃; for 2h;	100%

ethyl 3-ethoxypropionate (763-69-9) + N-propyl-toluene-4-sulfonamide (1133-12-6) → C15H25NO3S (1391911-31-1)

Conditions	Yield
With 1,1,3,3-Tetramethyldisiloxane; (Ace)Ru3(CO)7 In dichloromethane at 20℃; for 20h; Inert atmosphere;	99%

ethyl 3-ethoxypropionate (763-69-9) + N-benzyl-p-toluenesulfonamide (1576-37-0) → C19H25NO3S (1391911-32-2)

Conditions	Yield
With 1,1,3,3-Tetramethyldisiloxane; (Ace)Ru3(CO)7 In dichloromethane at 20℃; for 20h; Inert atmosphere;	99%

ethyl 3-ethoxypropionate (763-69-9) + 4-methyl-N-pentylbenzenesulfonamide (106011-68-1) → C17H29NO3S (1394028-60-4)

Conditions	Yield
With 1,1,3,3-Tetramethyldisiloxane; (Ace)Ru3(CO)7 In dichloromethane at 20℃; for 20h; Inert atmosphere;	99%

ethyl 3-ethoxypropionate (763-69-9) + 4-methyl-N-(3-methylbut-2-enyl)benzenesulfonamide (78388-19-9) → C17H27NO3S (1394028-61-5)

Conditions	Yield
With 1,1,3,3-Tetramethyldisiloxane; (Ace)Ru3(CO)7 In dichloromethane at 20℃; for 20h; Inert atmosphere;	99%

ethyl 3-ethoxypropionate (763-69-9) + N-methyl-p-toluenesulfonylamide (640-61-9) → C13H21NO3S (1391911-30-0)

Conditions	Yield
With 1,1,3,3-Tetramethyldisiloxane; (Ace)Ru3(CO)7 In dichloromethane at 20℃; for 20h; Inert atmosphere;	99%

ethyl 3-ethoxypropionate (763-69-9) → 3-Ethoxypropionsaeurehydrazid (37952-36-6)

Conditions	Yield
With hydrazine In ethanol; water Reflux;	85%

bromobenzene (108-86-1) + ethyl 3-ethoxypropionate (763-69-9) → 3-ethoxy-1,1-diphenylpropan-1-ol

Conditions	Yield
With magnesium; copper(II) oxide In tetrahydrofuran at 65℃; for 4h; Barbier Coupling Reaction; chemoselective reaction;	83%
With magnesium; copper(II) oxide In tetrahydrofuran at 65℃; for 4h; chemoselective reaction;	83%

ethyl 3-ethoxypropionate (763-69-9) + para-bromotoluene (106-38-7) → 3-ethoxy-1,1-di(p-tolyl)propan-1-ol (1541189-44-9)

Conditions	Yield
With magnesium; copper(II) oxide In tetrahydrofuran at 65℃; for 4h; Barbier Coupling Reaction; chemoselective reaction;	77%
With magnesium; copper(II) oxide In tetrahydrofuran at 65℃; for 4h; chemoselective reaction;	77%

2,3-Diaminopyridine (452-58-4) + ethyl 3-ethoxypropionate (763-69-9) → 2-(2-ethoxyethyl)-3H-imidazo[4,5-b]pyridine (1235235-73-0)

Conditions	Yield
With lithium bromide at 110 - 115℃; for 9h; Neat (no solvent);	75%

ethyl 3-ethoxypropionate (763-69-9) + toluene-4-sulfonamide (70-55-3) → C17H29NO4S (1391911-29-7)

Conditions	Yield
With 1,1,3,3-Tetramethyldisiloxane; (Ace)Ru3(CO)7 In dichloromethane at 20℃; for 20h; Inert atmosphere;	72%

ethyl 3-ethoxypropionate (763-69-9) + 1,2-diamino-benzene (95-54-5) → 2-(2-ethoxy-ethyl)-1H-benzimidazole (51036-80-7)

Conditions	Yield
With lithium bromide at 110 - 115℃; for 10h; Neat (no solvent);	70%
With hydrogenchloride

ethyl 3-ethoxypropionate (763-69-9) + 1,2-dibromomethane (74-95-3) → 1,1-dibromo-4-ethoxy-2-butanone

Conditions	Yield
With 2,2,6,6-tetramethyl-piperidine; n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.166667h;	67%

morpholine (110-91-8) + ethyl 3-ethoxypropionate (763-69-9) → β-ethoxy-N-morpholinylpropionamide

Conditions	Yield
With iron(II) triflate at 0 - 80℃; under 760.051 Torr; for 1h; Autoclave;	62%

ethyl 3-ethoxypropionate (763-69-9) + dimethyl sulfate (77-78-1) + formic acid ethyl ester (109-94-4) → (Z)-ethyl-2-(ethoxymethyl)-3-methoxyacrylate (2974-30-3)

Conditions	Yield
Stage #1: ethyl 3-ethoxypropionate; formic acid ethyl ester With ethanol; sodium In benzene at 0℃; for 2h; Claisen condensation; Stage #2: dimethyl sulfate In benzene at 50℃; for 3h;	58%
Stage #1: ethyl 3-ethoxypropionate; formic acid ethyl ester With sodium ethanolate In toluene at 0℃; for 2h; Inert atmosphere; Stage #2: dimethyl sulfate In toluene at 0 - 50℃; for 12h; Inert atmosphere;	52%
Stage #1: ethyl 3-ethoxypropionate; formic acid ethyl ester With ethanol; sodium In benzene at 0 - 20℃; for 2h; Stage #2: dimethyl sulfate In benzene at 50℃; for 3h; Stage #3: With triethylamine hydrochloride; sodium hydroxide In benzene for 4h;	33%
(i) NaOEt, EtOH, (ii) /BRN= 635994/; Multistep reaction;
Stage #1: ethyl 3-ethoxypropionate; formic acid ethyl ester With sodium In ethanol; benzene at 0℃; for 2h; Stage #2: dimethyl sulfate In ethanol; benzene at 50℃; for 3h;

ethyl 3-ethoxypropionate (763-69-9) + formic acid ethyl ester (109-94-4) → (Z)-ethyl-2-(ethoxymethyl)-3-methoxyacrylate

Conditions	Yield
Stage #1: ethyl 3-ethoxypropionate; formic acid ethyl ester With sodium In ethanol; hexane at 0 - 20℃; for 3h; Stage #2: With triethylamine hydrochloride; sodium hydroxide at 20℃; for 4h;	56%

2-bromo-pyridine (109-04-6) + ethyl 3-ethoxypropionate (763-69-9) → 3-ethoxy-1-(pyridin-2-yl)propan-1-one

Conditions	Yield
Stage #1: 2-bromo-pyridine With n-butyllithium In diethyl ether; hexane at -78℃; for 0.5h; Stage #2: ethyl 3-ethoxypropionate In diethyl ether; hexane at -78℃; for 1h;	54%
Stage #1: 2-bromo-pyridine With n-butyllithium In diethyl ether; hexane at -78℃; for 0.5h; Stage #2: ethyl 3-ethoxypropionate In diethyl ether; hexane at -78℃; for 1h;	54%

ethyl 3-ethoxypropionate (763-69-9) → glyoxylic acid ethyl ester (924-44-7) + 3-oxo-propionic acid ethyl ester (34780-29-5) + acetaldehyde (75-07-0) + 3-Formyloxy-propionic acid ethyl ester + formic acid ethyl ester (109-94-4)

Conditions	Yield
With dodecane; methyl nitrite; nitrogen(II) oxide at 23.9℃; under 760 Torr; Rate constant; Product distribution; Mechanism; Irradiation;	A 25% B 4.8% C 4.9% D 30% E 37%

ethyl 3-ethoxypropionate (763-69-9) + dimethyl sulfate (77-78-1) + formic acid ethyl ester (109-94-4) → (Z)-ethyl-2-(ethoxymethyl)-3-methoxyacrylate (879008-23-8)

Conditions	Yield
Stage #1: ethyl 3-ethoxypropionate; formic acid ethyl ester With sodium In ethanol; hexane at 0 - 20℃; Stage #2: dimethyl sulfate In hexane at 50℃; for 2h; Cooling with ice; Stage #3: With triethylamine hydrochloride; sodium hydroxide In hexane at 20℃; for 4h;	37%
Stage #1: ethyl 3-ethoxypropionate; formic acid ethyl ester With ethanol; sodium In hexane at 0 - 20℃; Stage #2: dimethyl sulfate In hexane at 50℃; for 2h; Cooling with ice;	37%
Stage #1: ethyl 3-ethoxypropionate; formic acid ethyl ester With ethanol; sodium In benzene at 0℃; for 2h; Stage #2: dimethyl sulfate In benzene at 50℃; for 3h; Stage #3: With triethylamine hydrochloride; sodium hydroxide In benzene for 4h;	33%
Stage #1: ethyl 3-ethoxypropionate; dimethyl sulfate; formic acid ethyl ester With ethanol; sodium In benzene at 0 - 50℃; for 5h; Stage #2: With triethylamine hydrochloride; sodium hydroxide In benzene for 4h;	33%
Stage #1: ethyl 3-ethoxypropionate; formic acid ethyl ester With sodium ethanolate In hexane at 0 - 20℃; Stage #2: dimethyl sulfate In hexane at 50℃; for 2h; Cooling with ice;

4-cyclopentylamino-2-methylsulfanyl-pyrimidine-5-carbaldehyde (211245-64-6) + ethyl 3-ethoxypropionate (763-69-9) → 8-cyclopentyl-6-ethoxymethyl-2-methylsulfanyl-8H-pyrido[2,3-d]pyrimidin-7-one (571189-94-1)

Conditions	Yield
Stage #1: ethyl 3-ethoxypropionate With lithium hexamethyldisilazane In tetrahydrofuran Stage #2: 4-cyclopentylamino-2-methylsulfanyl-pyrimidine-5-carbaldehyde In tetrahydrofuran for 24h;	35%
In tetrahydrofuran; ethyl acetate	34.9%

ethyl 3-ethoxypropionate (763-69-9) + dimethyl sulfate (77-78-1) + formic acid ethyl ester (109-94-4) → (z)-ethyl-2-(ethoxymethyl)-3-methoxyacrylate

Conditions	Yield
Stage #1: ethyl 3-ethoxypropionate; formic acid ethyl ester With ethanol; sodium In benzene at 0 - 20℃; for 2h; Stage #2: dimethyl sulfate In benzene at 50℃; for 3h; Stage #3: With sodium hydroxide; water; triethylamine hydrochloride In benzene for 4h;	33%

Upstream product

• 57-57-8 β-Propiolactone 
• 64-17-5 ethanol 
• 141-52-6 sodium ethanolate 
• 623-71-2 ethyl 3-chloropropanoate 
• 140-88-5 ethyl acrylate 
• 503-66-2 3-hydroxypropionic acid 
• 67-64-1 acetone 
• 9004-34-6 cellulose 
• 3586-58-1 2-methylenebutyric acid 
• 917-58-8 potassium ethoxide 
• 462-95-3 formaldehyde diethyl acetal 
• 89180-39-2 3-bromo-1,1,1-trichloro-3-ethoxy-propane 
• 111-13-7 hexyl-methyl-ketone 
• 109-95-5 ethyl nitrite 

Downstream Products

• 14144-41-3 β-Propoxy-propionsaeure-propylester 
• 30354-97-3 6-(2-ethoxy-ethyl)-[1,3,5]triazine-2,4-diyldiamine 
• 51036-80-7 2-(2-ethoxy-ethyl)-1H-benzimidazole 
• 875318-46-0 ethyl 2-(4-(hydroxymethyl)piperidin-1-yl )pyrimidine-5-carboxylate 
• 1552310-52-7 2-chloro-4-(((5-(ethoxycarbonyl)pyrimidin-2-yl)(methyl)amino)methyl)benzoic acid 
• 1552310-58-3 ethyl 2-(3-chloro-4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)phenyl sulfonamido)pyrimidine-5-carboxylate 
• 1552310-69-6 ethyl 2-(4-((3-chloro-4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)phenyl sulfonamido)methyl)piperidin-1-yl)pyrimidine-5-carboxylate 
• 60044-74-8 4-ethoxy-butan-2-one 
• 37952-36-6 3-Ethoxypropionsaeurehydrazid 
• 73-66-5 5-ethoxymethyl-2-methyl-pyrimidin-4-ylamine 
• 1235451-75-8 ethyl 2-(methyl((4-morpholino-2-(1H-pyrrol-3-yl)thieno[3,2-d]pyrimidin-6-yl)methyl)amino)pyrimidine-5-carboxylate 
• 1235451-59-8 ethyl 2-(((2-(3,4-diaminophenyl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)(methyl)amino)pyrimidine-5-carboxylate 
• 1235451-42-9 ethyl 2-(methyl((4-morpholino-2-phenylthieno[3,2-d]pyrimidine-6-yl)methyl)amino)pyrimidine-5-carboxylate 
• 95928-49-7 2-hydroxy-pyrimidine-5-carboxylic acid ethyl ester 

Relevant articles and documents

Synthesis method of ethyl 3-ethoxypropionate

The invention relates to a synthesis method of ethyl 3-ethoxypropionate, which comprises the following steps of carrying out addition reaction on absolute ethyl alcohol and ethyl acrylate in the presence of a catalyst which is a micromolecular tertiary amine catalyst, after the reaction is finished, removing excessive absolute ethyl alcohol, unreacted ethyl acrylate and the catalyst through rectification, collecting ethyl 3-ethoxypropionate with the purity being greater than 99.8% as a product, and recycling the collected excessive absolute ethyl alcohol, unreacted ethyl acrylate and the catalyst in the next reaction. The synthesis method has the advantages of simple synthesis, mild conditions, no need of acid neutralization, few side reactions, no three wastes, high conversion rate, long-term use of the catalyst, repeated cyclic utilization, no damage, simplified separation process, good product quality, easy obtainment of 99.8% or above of purity, promotion of large-scale production,and facilitation of large-scale application to the photoelectric industry.

Method for producing Alkyl 3-Alkoxypropionate Using Continuous Type Process

The invention relates to a process for preparing alkyl 3 - alkoxypropionates. More particularly, it relates to a continuous process for preparing ethyl 3 - ethoxypropionate. A method for preparing an alkyl 3 - alkoxypropionate for a semiconductor is provided to produce alkyl 3 - alkoxypropionate for a semiconductor on a large scale using a continuous reaction, and to prepare an alkyl 3 - 3 - alkoxypropionate for a semiconductor in a large scale production process using a continuous method.

Method for producing Ethyl 3-Ethoxypropionate

The present invention relates to a method for manufacturing ethyl 3-ethoxypropionate (EEP), comprising a step of synthesizing EEP with an ethyl acrylate monomer and ethanol in the presence of a catalyst, and then efficiently regenerating unreacted ethanol and the ethyl acrylate monomer from a reaction product obtained by removing a salt. It is possible to increase economic feasibility of EEP by efficiently regenerating and reusing, especially, ethanol among reaction products.COPYRIGHT KIPO 2019