112197-16-7

Basic information

• Product Name: 3-Pyridinemethanol,2-methoxy-(9CI)
• Synonyms: 3-Pyridinemethanol,2-methoxy-(9CI);(2-Methoxy-3-pyridinyl)methanol;(2-Methoxypyridin-3-yl)methanol;3-Hydroxymethyl-2-methoxypyridine;2-Methoxypyridine-3-methanol;(2-Methoxypyridin-3-yl);3-Pyridinemethanol, 2-methoxy-
• CAS NO: 112197-16-7
• Molecular Formula: C₇H₉NO₂
• Molecular Weight: 139.153
• Product Categories: PYRIDINE
• Mol File: 112197-16-7.mol
• Article Data: 16

Chemical Properties

• Melting Point: lowmeltsolid°
• Boiling Point: 242℃
• Flash Point: 100℃
• Appearance: /
• Density: 1.155
• Vapor Pressure: 0.019mmHg at 25°C
• Refractive Index: 1.534
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 13.20±0.10(Predicted)
• CAS DataBase Reference: 3-Pyridinemethanol,2-methoxy-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinemethanol,2-methoxy-(9CI)(112197-16-7)
• EPA Substance Registry System: 3-Pyridinemethanol,2-methoxy-(9CI)(112197-16-7)

Safety Data

• RIDADR: UN2811
• HazardClass: IRRITANT
• Hazardous Substances Data: 112197-16-7(Hazardous Substances Data)

Usage

General Description

3-Pyridinemethanol, 2-methoxy- (9CI) is a chemical compound with the molecular formula C7H9NO2. It is also known as 2-methoxypyridine-3-methanol and belongs to the class of organic compounds known as phenols. This chemical is commonly used in the production of pharmaceuticals and agricultural chemicals. It has a wide range of applications including as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Additionally, it is used as a flavoring agent and in the manufacture of fragrance and flavor chemicals. 3-Pyridinemethanol, 2-methoxy- (9CI) is also used in the manufacture of various personal care products.

InChI:InChI=1/C7H9NO2/c1-10-7-6(5-9)3-2-4-8-7/h2-4,9H,5H2,1H3

Upstream product

• 50-00-0 formaldehyd 
• 163105-90-6 2-methoxypyridin-3-yl-boronic acid 
• 40134-18-7 methyl 2-chloropyridine-3-carboxylate 
• 2942-59-8 2-chloronicotinic acid 
• 49609-84-9 2-Chloronicotinoyl chloride 
• 16498-81-0 2-methoxynicotinic acid 
• 71255-09-9 2-methoxynicotinaldehyde 
• 67367-26-4 2-methoxynicotinic acid methyl ester 
• 110-88-3 1,3,5-Trioxan 
• 1628-89-3 2-methoxypyridine 

Downstream Products

• 1020104-70-4 3-(4'-bromo-biphenyl-4-yloxymethyl)-2-methoxy-pyridine 
• 351410-38-3 2-(2-methoxy-3-pyridyl)acetic acid 
• 351410-37-2 (2-methoxypyridin-3-yl)acetonitrile 
• 1361225-10-6 2-((2-methoxy-3-pyridinyl)methyl)piperazine 
• 1361225-05-9 ethyl N-(diphenylmethylidene)-3-(2-methoxy-3-pyridinyl)alaninate 
• 1361225-04-8 1,1,1,3,3,3-hexafluoro-2-(4-(2-((2-methoxy-3-pyridinyl)methyl)-4-(2-thiophenylsulfonyl)-1-piperazinyl)phenyl)-2-propanol 
• 942060-13-1 3-(bromomethyl)-2-methoxypyridine 
• 178982-36-0 2-benzyloxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(2-methoxypyridin-3-ylmethyl)-1H-imidazole 
• 162046-62-0 2-methoxy-pyridin-3-ylmethyl chloride 
• 42463-41-2 2-hydroxy-3-hydroxymethylpyridine 

Relevant articles and documents

PYRIDINONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS AGAINST HIV INFECTED CELLS

The present disclosure is directed to pyridinone derivatives of Formula I and their use for selectively killing HIV infected GAG-POL expressing cells without concomitant cytotoxicity to HIV nave cells, and for the treatment of infection by HIV, or for the treatment, prophylaxis or delay in the onset or progression of AIDS or AIDS Related Complex (ARC).

ISOQUINOLINES AS INHIBITORS OF HPK1

Isoquinoline compounds and their use as inhibitors of HPK1 (hematopoietic kinase 1) are described. The compounds are useful in treating HPK1-dependent disorders and enhancing an immune response. Also described are methods of inhibitng HPK1, methods of treating HPK1-dependent disorders, methods for enhancing an immune response, and methods for preparing the isoquinoline compounds.

Structure-activity relationships (SAR) and structure-kinetic relationships (SKR) of sulphone-based CRTh2 antagonists

Monocyclic and bicyclic ring systems were investigated as the "core" section of a series of diphenylsulphone-containing acetic acid CRTh2 receptor antagonists. A range of potencies were observed and single-digit nanomolar potencies were obtained in both the monocyclic and bicyclic cores. Residence times for the monocyclic compounds were very short. Some of the bicyclic cores displayed better residence times. A methyl group in the northern part of the core, between the head and tail was a necessary requirement for the beginnings of long residence times. Variations of the tail substitution maximised potencies and residence times.