1131-79-9

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 24165-60-4 1-(4-methoxyphenyl)but-3-en-1-ol 
• 624-31-7 4-tolyl iodide 
• 85234-21-5 1-(4-methoxyphenyl)but-3-en-1-one 
• 5123-13-7 5,5-dimethyl-2-phenyl-1,3,2-dioxaborinane 
• 17614-89-0 (2-(4-methoxyphenyl)-2-oxoethyl)triphenylphosphonium bromide 
• 75-07-0 acetaldehyde 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 696-62-8 para-iodoanisole 
• 64-17-5 ethanol 
• 111887-18-4 4-(4-methoxyphenyl)but-3-yn-2-ol 
• 100-07-2 4-methoxy-benzoyl chloride 
• 762-72-1 allyl-trimethyl-silane 
• 67-56-1 methanol 

Downstream Products

• 1109280-52-5 1-(4-methoxyphenyl)-3-(p-tolyl)butan-1-one 
• 1443527-03-4 (S)-1-(4-methoxyphenyl)-3-(p-tolyl)butan-1-one 
• 1613249-79-8 C₁₅H₁₈O₃ 
• 4023-80-7 1-(4-methoxyphenyl)butan-1,3-dione 
• 1374988-85-8 (S)-1-(4-methoxyphenyl)-3-[2-((E)-2-phenylethenyl)phenyl]butan-1-one 
• 1008533-94-5 C₂₂H₃₄O₂Si 
• 147024-45-1 CH₃OC₆H₄C(O)CH₂CH(CH₃)Pb(C₄H₉)3 

Relevant academic research and scientific papers

InBr3-Catalyzed Alkynylation and Allylation of Acid Chlorides: A Facile Synthesis of Alkynyl and Allyl Ketones

Alkynylsilanes and allyltrimethylsilane undergo smooth coupling with acid chlorides in the presence of 5 mol% of indium tribromide under mild conditions to afford the corresponding α,β-acetylenic ketones and β,γ-unsaturated ketones in excellent yields in a short reaction time with high selectivity.

Method for preparing phenyl propenone compound by catalyzing phenylacetylene through molecular sieve

The invention belongs to the field of molecular sieve catalysis and organic synthesis, and discloses a method for preparing a phenyl propenone compound by catalyzing phenylacetylene through a molecular sieve, which comprises the following steps: adding a phenylacetylene compound I, aldehyde II and a molecular sieve catalyst into a small reaction kettle without adding an organic solvent and any other assistants; performing stirring to react for 0.25-6 hours under the condition of heating at 30-90 DEG C, cooling the reaction kettle to room temperature, performing diluting with ethyl acetate, andcentrifugally separating the catalyst to obtain the phenyl allyl ketone compound III. The molecular sieve catalyst provided by the invention is H-beta of which the silica-alumina ratios are respectively 14 and 29. The method is simple in reaction process, high in catalytic activity and selectivity, recyclable, environmentally friendly and capable of achieving large-scale industrial production.

Ni-Catalyzed 1,2-Diarylation of Alkenyl Ketones: A Comparative Study of Carbonyl-Directed Reaction Systems

A nickel-catalyzed 1,2-diarylation of alkenyl ketones with aryl iodides and arylboronic esters is reported. Ketones with a variety of substituents serve as effective directing groups, offering high levels of regiocontrol. A representative product is diversified into a wide range of useful products that are not readily accessible via existing 1,2-diarylation reactions. Preliminary mechanistic studies shed light on the binding mode of the substrate, and Hammett analysis reveals the effect of electronic factors on initial rates.

Efficient and regioselective one-step synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a] pyrimidine derivatives

Two facile and efficient one-step procedures for the regioselective synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a]pyrimidines have been developed, via reactions of 3,5-diamino-1,2,4-triazole with variously substituted 1-a

A mild isomerization reaction for β,γ-unsaturated ketone to α,β-unsaturated ketone

A series of β,γ-unsaturated ketones were isomerized to their corresponding α,β-unsaturated ketones by the introduction of DABCO in iPrOH at room temperature. The endo-cyclic double bond (β,γ-position) on ketone was rearranged to exo-cyclic double bond (α,β-position) under the reaction conditions.

Bi(OTf)3-catalyzed tandem Meyer-Schuster rearrangement and 1,4-addition to the resulting vinyl ketone

Bi(OTf)3-catalyzed Meyer-Schuster rearrangement of electron-rich propargyl alcohols, followed by 1,4-addition of the resulting vinyl ketone, proceeded smoothly though Meyer-Schuster rearrangement of primary propargyl alcohols is rare. This tandem reaction can be extended to an intramolecular version, featuring a one-pot dihydroquinolone synthesis. (Chemical Equation Presented).

Gold meets rhodium: Tandem one-pot synthesis of β-disubstituted ketones via meyer-schuster rearrangement and asymmetric 1,4-addition

An asymmetric one-pot tandem Au/Rh-catalyzed synthesis of highly enantioenriched β-disubstituted ketones starting from racemic propargyl alcohols is disclosed. The compatibility of the two metal complexes (Au/Rh) and their orthogonal ligand systems (NHC/d

A new organic transformation by introducing crotyl/allyltrifluoroborates in cross-coupling reaction with aroyl chlorides

Microwave irradiated PdCl2(dtbpf) catalyzed direct cross-coupling reaction of aroyl chlorides with potassium crotyl/ allyltrifluoroborates has been developed. Regioselectivity of the cross-coupling product is varied from crotyltrifluoroborate to allyltrifluoroborate.

Synthesis of β-Amino and β-Methoxy Ketones by Lewis Acids Promoted β-Substitution Reactions of βγ,-Unsaturated Ketones

A reaction mixture of β,γ-unsaturated ketone and BF 3·OEt2 in CH3OH was stirred at room temperature and β-methoxy ketone was produced in high yield. The β-amino ketone was obtained as the major product from a reaction mixture of β,γ-unsaturated ketone, AlCl3 and Ts-NH2 in CH2Cl2 at room temperature. This Lewis acid promoted β-substitution reaction mechanism was proposed as that the process occurred via in situ isomerization of β,γ-unsaturated ketone to α,β-unsaturated ketone followed by the 1,4-addition reaction.

COBALT(II)CHLORIDE CATALYSED ACYLATION OF ANISOLE

Cobalt(II)chloride catalysed acylation of anisole with variety of acid chlorides proceeds via an acyl radical to give p-acylated anisoles in good yields.