1156-50-9

Basic information

• Product Name: BIS(4-NITROPHENYL) SULFONE
• Synonyms: 1,1’-sulfonylbis(4-nitro-benzen;1,1’-sulfonylbis(4-nitrobenzene);4-nitrophenylsulfone;sulfone,bis(p-nitrophenyl);BIS(4-NITROPHENYL) SULFONE;DI-(P-NITROPHENYL)-SULFON;4,4'-DINITRODIPHENYL SULFONE;bis(4-nitrophenyl) sulphone
• CAS NO: 1156-50-9
• Molecular Formula: C₁₂H₈N₂O₆S
• Molecular Weight: 308.27
• EINECS: 214-589-9
• Product Categories: Diphenyl Sulfones (for High-Performance Polymer Research);Functional Materials;Reagent for High-Performance Polymer Research
• Mol File: 1156-50-9.mol
• Article Data: 25

Chemical Properties

• Melting Point: 178-185°C
• Boiling Point: 541.1°C at 760 mmHg
• Flash Point: 281°C
• Appearance: /
• Density: 1.53g/cm³
• Vapor Pressure: 3.18E-11mmHg at 25°C
• Refractive Index: 1.637
• Storage Temp.: Refrigerator
• Solubility: Acetonitrile (Slightly), DMSO (Slightly)
• CAS DataBase Reference: BIS(4-NITROPHENYL) SULFONE(CAS DataBase Reference)
• NIST Chemistry Reference: BIS(4-NITROPHENYL) SULFONE(1156-50-9)
• EPA Substance Registry System: BIS(4-NITROPHENYL) SULFONE(1156-50-9)

Safety Data

• Statements: 20/21/22
• Safety Statements: 22-36/37/39
• RTECS: WR4700000
• TSCA: Yes
• Hazardous Substances Data: 1156-50-9(Hazardous Substances Data)

Usage

General Description

BIS(4-NITROPHENYL) SULFONE is a chemical compound with the molecular formula C12H8N2O6S. It is a yellow crystalline powder that is commonly used as a precursor in the synthesis of various organic compounds, pharmaceuticals, and dyes. BIS(4-NITROPHENYL) SULFONE is also used as a crosslinking agent for polymers, as well as a stabilizer in plastics and rubbers. BIS(4-NITROPHENYL) SULFONE is known for its high thermal stability and resistance to oxidation, making it a valuable additive in a wide range of industrial and commercial applications. However, it is important to handle this compound with care, as it is considered to be toxic and may cause irritation to the skin, eyes, and respiratory system upon exposure.

InChI:InChI=1/C12H8N2O6S/c15-13(16)9-1-5-11(6-2-9)21(19,20)12-7-3-10(4-8-12)14(17)18/h1-8H

Upstream product

• 100-32-3 di(p-nitrophenyl) disulfide 
• 1223-31-0 bis(4-nitrophenyl)sulfide 
• 71-43-2 benzene 
• 1849-36-1 para-nitrobenzenethiol 
• 15959-31-6 sodium 4-nitrobenzenesulfinate 
• 100-00-5 4-chlorobenzonitrile 
• 139-66-2 diphenyl sulfide 
• 586-78-7 para-nitrophenyl bromide 
• 636-98-6 p-nitrobenzene iodide 
• 1774-38-5 4,4'-dinitrodiphenyl sulfoxide 
• 30388-70-6 2,2'-dinitrophenyl sulphoxide 

Downstream Products

• 383-29-9 bis(p-fluorophenyl)sulfone 
• 115166-72-8 bis-{4-[(N-acetyl-sulfanilyl)-amino]-phenyl}-sulfone 
• 119-59-5 4,4'-sulfinyldianiline 
• 36679-41-1 4,4'-bis(N,O-diacetylhydroxylamino)diphenyl sulfone 
• 77-46-3 acedapsone 
• 100-32-3 di(p-nitrophenyl) disulfide 
• 1223-31-0 bis(4-nitrophenyl)sulfide 
• 74236-92-3 4-Nitro-benzenethiosulfonic acid; compound with ammonia 
• 80-08-0 dapsone 
• 36679-40-0 dapsone dihydroxylamine 
• 1948-92-1 4-(4-nitrophenylsulfonyl)aniline 

Relevant articles and documents

An efficient method for the oxidation of sulfides to sulfones

Ruthenium trichloride - sodium periodate is a highly efficient and powerful system for the oxidation of unreactive sulfides to sulfones.

Selective synthesis of sulfoxides and sulfones by methyltrioxorhenium-catalyzed oxidation of sulfides with hydrogen peroxide

Methyltrioxorhenium-catalyzed oxidation of sulfides with hydrogen peroxide in ethanol has been found to be an efficient catalytic system for the selective formation of sulfoxides and sulfones. The oxidation using an equimolar amount of hydrogen peroxide afforded sulfoxides in excellent yield, and the use of two molar amounts of hydrogen peroxide gave sulfones quantitatively. Strongly deactivated sulfide, bis(4-nitrophenyl) sulfide, was converted smoothly to the corresponding sulfoxide and sulfone in excellent yields. The functional group in the side chain of sulfide such as a carbon-carbon double bond was not affected under the reaction conditions, and the sulfur atom was selectively oxidized.

Tris(hydroxymethyl)aminomethane modified layered double hydroxides greatly facilitate polyoxometalate intercalation

Polyoxometalate (POM) intercalation to layered double hydroxides (LDHs) has been greatly restricted by the geometry, charge and size of POMs. We report herein, for the first time, the intercalation of Na3[PW12O40]·15H2O into tris(hydroxymethyl)-aminomethane (Tris) modified layered double hydroxides (Tris-LDH-CO3) using an ion exchange method, resulting in the formation of novel intercalated Tris-LDH-PW12 under ambient conditions without the necessity of degassing CO2. Theoretical calculations show the decreased energy and the slightly distorted LDH layer after Tris modification, indicating that the Tris-modified LDH layers greatly facilitate the intercalation of PW12. Further application of Tris-LDH-PW12 for oxygenation of sulfides shows highly efficient and selective catalytic activities under mild conditions. The Tris-LDH-PW12 can be easily recovered and reused for more than 10 times without any obvious decrease of reactivity. This opens a completely new pathway for engineering POM-LDH advanced functional materials. This journal is

An Efficient Oxidation of Sulfides to Sulfones with Urea-Hydrogen Peroxide in the Presence of Phthalic Anhydride in Ethyl Acetate

A metal-free, environmentally benign oxidation of substituted sulfides directly to their corresponding sulfones is described. Using urea-hydrogen peroxide and phthalic anhydride in ethyl acetate clean conversion into the sulfone was achieved without observation of the possible sulfoxide oxidation product.