121352-96-3

Upstream product

• 202406-55-1 (R)-1-(2-Allyl-[1,3]dithian-2-yl)-4-benzyloxy-3,3-dimethyl-butan-2-ol 
• 909016-28-0 (R)-8-Benzyloxy-6-hydroxy-7,7-dimethyl-oct-1-en-4-one 
• 909016-29-1 (3R,5S)-1-(benzyloxy)-2,2-dimethyloct-7-ene-3,5-diol 
• 111080-21-8 (S)-2-(2-Benzyloxy-1,1-dimethyl-ethyl)-oxirane 
• 126-30-7 2,2-Dimethyl-1,3-propanediol 
• 121352-88-3 [(2R,3R)-3-(2-Benzyloxy-1,1-dimethyl-ethyl)-oxiranyl]-methanol 
• 111043-54-0 [(2R,3S,2'S,3'R)-3'-(2-Benzyloxy-1,1-dimethyl-ethyl)-[2,2']bioxiranyl-3-yl]-methanol 
• 121352-90-7 (E)-3-[(2R,3R)-3-(2-Benzyloxy-1,1-dimethyl-ethyl)-oxiranyl]-propenal 
• 121352-89-4 (2S,3R)-3-(2-Benzyloxy-1,1-dimethyl-ethyl)-oxirane-2-carbaldehyde 
• 121352-87-2 (E)-5-(benzyloxy)-4,4-dimethylpent-2-en-1-ol 
• 38216-93-2 3-benzyloxypivalic aldehyde 
• 66582-32-9 3-(benzyloxy)-2,2-dimethylpropan-1-ol 
• 776-88-5 5,5-dimethyl-2-phenyl-[1,3]dioxane 
• 121352-95-2 2-<(4R,6S)-6-(2-benzyloxy-1,1-dimethylethyl)-2,2-dimethyl-1,3-dioxan-4-yl>ethanol 

Downstream Products

• 909016-30-4 4-[(4S,6R)-6-(2-Benzyloxy-1,1-dimethyl-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-3-hydroxy-2-methyl-butyric acid methyl ester 
• 909016-43-9 2-[(2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-((3E,7E)-(R)-2-hydroxy-1,1,4-trimethyl-6-triethylsilanyloxy-10-trimethylsilanyl-deca-3,7-dien-9-ynyl)-2-methoxy-tetrahydro-pyran-2-yl]-propionic acid methyl ester 
• 909016-24-6 2-[(2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-((3E,7E)-(R)-2,6-dihydroxy-1,1,4-trimethyl-9-trityloxy-nona-3,7-dienyl)-2-methoxy-tetrahydro-pyran-2-yl]-propionic acid 
• 909016-41-7 2-[(2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-((3E,7E)-(R)-2-hydroxy-1,1,4-trimethyl-6-triethylsilanyloxy-9-trityloxy-nona-3,7-dienyl)-2-methoxy-tetrahydro-pyran-2-yl]-propionic acid methyl ester 
• 202406-61-9 2-[(2S,4R,6R)-6-(2-Benzyloxy-1,1-dimethyl-ethyl)-4-hydroxy-2-methoxy-tetrahydro-pyran-2-yl]-propionic acid methyl ester 
• 202406-60-8 4-[(4R,6R)-6-(2-Benzyloxy-1,1-dimethyl-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-2-methyl-3-oxo-butyric acid methyl ester 
• 909016-32-6 2-[(2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-(2-hydroxy-1,1-dimethyl-ethyl)-2-methoxy-tetrahydro-pyran-2-yl]-propionic acid methyl ester 
• 202406-63-1 2-[(2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-(1,1-dimethyl-2-oxo-ethyl)-2-methoxy-tetrahydro-pyran-2-yl]-propionic acid methyl ester 
• 909016-31-5 2-[(2S,4R,6R)-6-(2-Benzyloxy-1,1-dimethyl-ethyl)-4-(tert-butyl-diphenyl-silanyloxy)-2-methoxy-tetrahydro-pyran-2-yl]-propionic acid methyl ester 
• 909016-48-4 (E)-(1S,2S,5R,11R,13R)-5-((1E,3E)-4-Bromo-buta-1,3-dienyl)-13-(tert-butyl-diphenyl-silanyloxy)-1-hydroxy-2,7,10,10-tetramethyl-4,15-dioxa-bicyclo[9.3.1]pentadec-7-ene-3,9-dione 
• 202406-76-6 (E)-(1S,2S,5R,11R,13R)-5-((1E,3Z)-4-Bromo-buta-1,3-dienyl)-13-(tert-butyl-diphenyl-silanyloxy)-1-hydroxy-2,7,10,10-tetramethyl-4,15-dioxa-bicyclo[9.3.1]pentadec-7-ene-3,9-dione 
• 202406-73-3 (E)-(1S,2S,5R,11R,13R)-13-(tert-Butyl-diphenyl-silanyloxy)-1-hydroxy-5-hydroxymethyl-2,7,10,10-tetramethyl-4,15-dioxa-bicyclo[9.3.1]pentadec-7-ene-3,9-dione 
• 202406-67-5 2-[(2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-((E)-(R)-2-hydroxy-1,1,4-trimethyl-6-triethylsilanyloxy-7-trityloxy-hept-3-enyl)-2-methoxy-tetrahydro-pyran-2-yl]-propionic acid methyl ester 
• 202406-69-7 2-[(2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-((E)-(R)-2,6-dihydroxy-1,1,4-trimethyl-7-trityloxy-hept-3-enyl)-2-methoxy-tetrahydro-pyran-2-yl]-propionic acid 

Relevant academic research and scientific papers

Enantioselective synthesis of aurisides A and B, cytotoxic macrolide glycosides of marine origin

The enantioselective synthesis of aurisides A and B, macrolide glycosides of marine origin, was achieved by a convergent approach. The C1-C9 segment 4 was prepared from (R)-pantolactone, and the C10-C17 segment 14 was synthesized from (R)-glycidyl trityl

Synthesis of the aglycon of aurisides A and B, cytotoxic macrolide glycosides of marine origin

The synthesis of the aglycon of aurisides A and B was achieved from (R)-pantolactone in 29 steps using the Nozaki reaction and the Yamaguchi macrolactonization as key steps.

Synthesis of Bryostatins. 1. Construction of the C(1)-C(16) Fragment

The synthesis of fragment AB of bryostatin 1 is described.Two aldol coupling reactions involving (i) chiral fragment A with achiral B and (ii) chiral fragment A1 with achiral A2 constitute crucial steps in which an external chiral boron reagent is used to control stereoselectivity in the creation of a new stereogenic center.This type of double asymmetric synthesis, although rarely precedented, provides a powerful means of stereocontrol over the fragment assembly.