121352-96-3

Upstream product

• 776-88-5 5,5-dimethyl-2-phenyl-[1,3]dioxane 
• 202406-55-1 (R)-1-(2-Allyl-[1,3]dithian-2-yl)-4-benzyloxy-3,3-dimethyl-butan-2-ol 
• 909016-28-0 (R)-8-Benzyloxy-6-hydroxy-7,7-dimethyl-oct-1-en-4-one 
• 909016-29-1 (3R,5S)-1-(benzyloxy)-2,2-dimethyloct-7-ene-3,5-diol 
• 111080-21-8 (S)-2-(2-Benzyloxy-1,1-dimethyl-ethyl)-oxirane 
• 202406-58-4 (4S,6R)-4-Allyl-6-(2-benzyloxy-1,1-dimethyl-ethyl)-2,2-dimethyl-[1,3]dioxane 
• 126-30-7 2,2-Dimethyl-1,3-propanediol 
• 100-52-7 benzaldehyde 
• 121352-88-3 [(2R,3R)-3-(2-Benzyloxy-1,1-dimethyl-ethyl)-oxiranyl]-methanol 
• 121352-94-1 2,2-Dimethyl-propionic acid 2-[(4R,6S)-6-(2-benzyloxy-1,1-dimethyl-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-ethyl ester 
• 121352-93-0 2,2-Dimethyl-propionic acid (3R,5S)-7-benzyloxy-3,5-dihydroxy-6,6-dimethyl-heptyl ester 
• 111043-54-0 [(2R,3S,2'S,3'R)-3'-(2-Benzyloxy-1,1-dimethyl-ethyl)-[2,2']bioxiranyl-3-yl]-methanol 
• 121352-91-8 (E)-3-[(2R,3R)-3-(2-Benzyloxy-1,1-dimethyl-ethyl)-oxiranyl]-prop-2-en-1-ol 
• 121352-92-9 (3R,5S)-7-Benzyloxy-6,6-dimethyl-heptane-1,3,5-triol 

Downstream Products

• 121352-98-5 (E)-4-[(4R,6S)-6-(2-Benzyloxy-1,1-dimethyl-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-but-2-en-1-ol 
• 121353-00-2 (S)-4-[(4R,6S)-6-(2-Benzyloxy-1,1-dimethyl-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-butane-1,3-diol 
• 121352-99-6 {(2R,3R)-3-[(4S,6S)-6-(2-Benzyloxy-1,1-dimethyl-ethyl)-2,2-dimethyl-[1,3]dioxan-4-ylmethyl]-oxiranyl}-methanol 
• 111043-56-2 2-{(4S,6R)-6-[(S)-4-(tert-Butyl-diphenyl-silanyloxy)-2-methoxymethoxy-butyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-2-methyl-propan-1-ol 
• 121353-03-5 3-{(4S,6R)-6-[(S)-4-(tert-Butyl-diphenyl-silanyloxy)-2-methoxymethoxy-butyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-3-methyl-butan-2-ol 
• 121353-02-4 2-{(4S,6R)-6-[(S)-4-(tert-Butyl-diphenyl-silanyloxy)-2-methoxymethoxy-butyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-2-methyl-propionaldehyde 
• 111070-65-6 3-{(4S,6R)-6-[(S)-4-(tert-Butyl-diphenyl-silanyloxy)-2-methoxymethoxy-butyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-3-methyl-butan-2-one 
• 121353-01-3 (S)-1-[(4R,6S)-6-(2-Benzyloxy-1,1-dimethyl-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-4-(tert-butyl-diphenyl-silanyloxy)-butan-2-ol 
• 121372-79-0 {(S)-4-[(4R,6S)-6-(2-Benzyloxy-1,1-dimethyl-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-3-methoxymethoxy-butoxy}-tert-butyl-diphenyl-silane 
• 121353-16-0 (R)-7-[2-(tert-Butyl-diphenyl-silanyloxy)-eth-(E)-ylidene]-2-{(4S,6R)-6-[(S)-4-(tert-butyl-diphenyl-silanyloxy)-2-methoxymethoxy-butyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-5-hydroxy-2-methyl-dec-9-en-3-one 
• 121353-16-0 (S)-7-[2-(tert-Butyl-diphenyl-silanyloxy)-eth-(E)-ylidene]-2-{(4S,6R)-6-[(S)-4-(tert-butyl-diphenyl-silanyloxy)-2-methoxymethoxy-butyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-5-hydroxy-2-methyl-dec-9-en-3-one 
• 909016-43-9 2-[(2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-((3E,7E)-(R)-2-hydroxy-1,1,4-trimethyl-6-triethylsilanyloxy-10-trimethylsilanyl-deca-3,7-dien-9-ynyl)-2-methoxy-tetrahydro-pyran-2-yl]-propionic acid methyl ester 
• 909016-24-6 2-[(2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-((3E,7E)-(R)-2,6-dihydroxy-1,1,4-trimethyl-9-trityloxy-nona-3,7-dienyl)-2-methoxy-tetrahydro-pyran-2-yl]-propionic acid 
• 909016-41-7 2-[(2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-((3E,7E)-(R)-2-hydroxy-1,1,4-trimethyl-6-triethylsilanyloxy-9-trityloxy-nona-3,7-dienyl)-2-methoxy-tetrahydro-pyran-2-yl]-propionic acid methyl ester 

Relevant academic research and scientific papers

Enantioselective synthesis of aurisides A and B, cytotoxic macrolide glycosides of marine origin

The enantioselective synthesis of aurisides A and B, macrolide glycosides of marine origin, was achieved by a convergent approach. The C1-C9 segment 4 was prepared from (R)-pantolactone, and the C10-C17 segment 14 was synthesized from (R)-glycidyl trityl

Synthesis of the aglycon of aurisides A and B, cytotoxic macrolide glycosides of marine origin

The synthesis of the aglycon of aurisides A and B was achieved from (R)-pantolactone in 29 steps using the Nozaki reaction and the Yamaguchi macrolactonization as key steps.

Synthesis of Bryostatins. 1. Construction of the C(1)-C(16) Fragment

The synthesis of fragment AB of bryostatin 1 is described.Two aldol coupling reactions involving (i) chiral fragment A with achiral B and (ii) chiral fragment A1 with achiral A2 constitute crucial steps in which an external chiral boron reagent is used to control stereoselectivity in the creation of a new stereogenic center.This type of double asymmetric synthesis, although rarely precedented, provides a powerful means of stereocontrol over the fragment assembly.