13054-83-6

Usage

Class

Chalcone

Type of Compound

α,β-unsaturated ketone

Usage

Organic synthesis and medicinal chemistry

Potential Therapeutic Applications

Treatment of various diseases, including cancer and inflammation

Demonstrated Activities

Anti-inflammatory, anti-cancer, and anti-bacterial

Preclinical Studies

Shown potential in treating various diseases

Structural and Reactive Properties

Valuable intermediate in the production of other pharmaceuticals and fine chemicals

Additional Applications

Investigated for use as an ingredient in cosmetics and personal care products

Upstream product

• 120-46-7 1,3-diphenylpropanedione 
• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 75-36-5 acetyl chloride 
• 64-19-7 acetic acid 
• 728-84-7 2-bromo-1,3-diphenylpropane-1,3-dione 
• 855754-86-8 α,β-diacetoxy-chalcone 

Downstream Products

• 855754-86-8 α,β-diacetoxy-chalcone 
• 135127-07-0 4-acetoxy-1-(2-hydroxyethyl)-3,5-diphenyl-1H-pyrazole 
• 17953-06-9 4-Hydroxy-3,5-diphenyl-1H-pyrazole 
• 54519-19-6 2,2-Diacetoxy-1,3-diphenylpropan-1,3-dion 
• 13054-61-0 3,5-diphenyl-isoxazol-4-ol 
• 643-75-4 1,3-diphenyl-propane-1,2,3-trione 
• 65-85-0 benzoic acid 
• 582-24-1 1-phenyl-2-hydroxyethanone 
• 60627-48-7 4-acetoxy-1-benzyl-3,5-diphenyl-1H-pyrazole 
• 34878-65-4 4-methoxy-3,5-diphenyl-isoxazole 
• 135127-08-1 tosylate of 4-acetoxy-1-(2-hydroxyethyl)-3,5-diphenyl-1H-pyrazole 
• 135127-14-9 1-[2-(4-Methyl-piperazin-1-yl)-ethyl]-3,5-diphenyl-1H-pyrazol-4-ol 
• 135127-13-8 1-(2-Morpholin-4-yl-ethyl)-3,5-diphenyl-1H-pyrazol-4-ol 
• 135127-12-7 3,5-Diphenyl-1-(2-piperidin-1-yl-ethyl)-1H-pyrazol-4-ol 

Relevant academic research and scientific papers

Oxidative α-Acetoxylation of a β-Oxime Ester with (Diacetoxyiodo)benzene Catalyzed by ScIII Salts: An Approach to the Docetaxel Side Chain

Hypervalent iodine(III) compounds have emerged as reagents of choice for α-oxidation of various ketones under mild reaction conditions. We report herein a simple method for α-hydroxylation of a β-oxime ester, which involves an oxidative α-acetoxylation us

Hypervalent iodine(III)-induced methylene acetoxylation of 3-oxo-n-substituted butanamides

1-Carbamoyl-2-oxopropyl acetate derivatives were synthesized through an acetoxylation process to methylene with the aid of (diacetoxyiodo)benzene (DIB) as the oxidant. Not only mild reaction conditions, but also excellent yields and good substrate scope m