131077-78-6

Basic information

• Product Name: 4-methyl-4-(trimethylsilyloxy)cyclohexanone
• Synonyms: 4-methyl-4-(trimethylsilyloxy)cyclohexanone
• CAS NO: 131077-78-6
• Molecular Weight: 200.353
• Mol File: 131077-78-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-methyl-4-(trimethylsilyloxy)cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-4-(trimethylsilyloxy)cyclohexanone(131077-78-6)
• EPA Substance Registry System: 4-methyl-4-(trimethylsilyloxy)cyclohexanone(131077-78-6)

Safety Data

• Hazardous Substances Data: 131077-78-6(Hazardous Substances Data)

Upstream product

• 54927-71-8 trimethyl((1-methylcyclohexyl)oxy)silane 
• 75-77-4 chloro-trimethyl-silane 
• 17429-02-6 4-hydroxy-4-methylcyclohexanone 
• 89794-52-5 1-methyl-1,4-cyclohexanediol 
• 10416-59-8 N,O-bis-(trimethylsilyl)-acetamide 
• 131057-03-9 1-methyl-4-tetrahydropyranyloxy-1-cyclohexanol 
• 13482-22-9 4-hydroxycyclohexanone 
• 60739-53-9 4-(tetrahydro-2H-pyran-2-yloxy)cyclohexanone 

Downstream Products

• 1141822-57-2 (1R,2S,5R)-8-phenylmenthyl (1R,5S)-1-benzyl-5-methyl-2-oxo-5-(trimethylsilyloxy)cycloheptanecarboxylate 
• 131077-81-1 4-[2-((3S,5S)-3,5-Dimethyl-2-oxo-5-trimethylsilanyloxy-cyclohexyl)-2-hydroxy-ethyl]-piperidine-2,6-dione 
• 131077-81-1 4-[2-((3R,5S)-3,5-Dimethyl-2-oxo-5-trimethylsilanyloxy-cyclohexyl)-2-hydroxy-ethyl]-piperidine-2,6-dione 
• 523-86-4 (+/-)-4-<2-(5-hydroxy-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl>-2,6-piperidindione 
• 523-86-4 (+/-)-4-<2-(5-hydroxy-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl>-2,6-piperidindione 
• 523-86-4 (+/-)-4-<2-(5-hydroxy-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl>-2,6-piperidindione 
• 523-86-4 (+/-)-4-<2-(5-hydroxy-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl>-2,6-piperidindione 
• 131057-04-0 Acetic acid (1R,3S,5S)-3-[(R)-2-(2,6-dioxo-piperidin-4-yl)-1-triethylsilanyloxy-ethyl]-1,5-dimethyl-4-oxo-cyclohexyl ester 
• 131057-05-1 4-[(R)-2-((1S,3S,5R)-5-Hydroxy-3,5-dimethyl-2-oxo-cyclohexyl)-2-triethylsilanyloxy-ethyl]-piperidine-2,6-dione 
• 2885-39-4 (+/-)-E-73 
• 131077-79-7 cis-2,4-dimethyl-4-trimethylsiloxy-1-cyclohexanone 
• 131077-79-7 trans-2,4-dimethyl-4-trimethylsiloxy-1-cyclohexanone 

Relevant articles and documents

Scalable, Electrochemical Oxidation of Unactivated C-H Bonds

A practical electrochemical oxidation of unactivated C-H bonds is presented. This reaction utilizes a simple redox mediator, quinuclidine, with inexpensive carbon and nickel electrodes to selectively functionalize "deep-seated" methylene and methine moieties. The process exhibits a broad scope and good functional group compatibility. The scalability, as illustrated by a 50 g scale oxidation of sclareolide, bodes well for immediate and widespread adoption.

Syntheses and biological activities of (+/-)-streptovitacin A and E-73.

(+/-)-Streptovitacin A (1) and its stereoisomers were synthesized by an aldol reaction of (+/-)-2,4-dimethyl-4-trimethylsiloxy-1-cyclohexanones (4b and 9) with 4-(2-oxoethyl)-2,6-piperidinedione (5). E-72 (2) was derived from synthetic 1. (+/-)-1 showed m