1311145-52-4Relevant articles and documents
Synthesis and in vitro antiproliferative evaluation of novel N-alkylated 6-isobutyl- and propyl pyrimidine derivatives
Gazivoda Kraljevi?, Tatjana,Ili?, Nata?a,Stepani?, Vi?nja,Sappe, Lana,Petranovi?, Jasna,Kraljevi? Paveli?, Sandra,Rai?-Mali?, Silvana
, p. 2913 - 2917 (2014/06/10)
A series of novel N-alkylated C-6-isobutyl- or -propyl pyrimidine derivatives were synthesized and their antiproliferative effect was evaluated on a panel of tumor cell lines including leukemia cell line K562 and normal diploid human fibroblasts. N-methox
Methoxymethyl (MOM) group nitrogen protection of pyrimidines bearing C-6 acyclic side-chains
Kraljevic, Tatjana Gazivoda,Petrovic, Martina,Kristafor, Svjetlana,Makuc, Damjan,Plavec, Janez,Ross, Tobias L.,Ametamey, Simon M.,Raic-Malic, Silvana
, p. 5113 - 5129 (2011/08/06)
Novel N-methoxymethylated (MOM) pyrimidine (4-13) and pyrimidine-2,4- diones (15-17) nucleoside mimetics in which an isobutyl side-chain is attached at the C-6 position of the pyrimidine moiety were synthesized. Synthetic methods via O-persilylated or N-a