134272-58-5

Upstream product

• 614-27-7 methyl 3-oxo-3-phenylpropionate 
• 107-07-3 2-chloro-ethanol 
• 98-86-2 acetophenone 
• 100-52-7 benzaldehyde 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 

Downstream Products

• 128592-71-2 2-(3-oxo-3-phenylpropylidene)-1,3-dioxolane 
• 93622-17-4 3-(oxo-ethylene acetal)-1-oxo-1-phenyl pentane 
• 111615-95-3 (E)-3-butoxy-1-phenyl-2-propen-1-one 
• 55337-53-6 1-phenyl-2-(2-phenyl-1,3-dioxolan-2-yl)-ethan-1-one 
• 128592-76-7 3-(oxo-ethylene acetal)-1-oxo-1-phenyl heptane 
• 128592-75-6 3-(oxo-ethylene acetal)-4,4-dimethyl-1-oxo-1-phenyl pentane 
• 87920-07-8 3-(oxo-ethylene acetal)-1-oxo-1-phenyl butane 
• 100058-84-2 2-(2'-hydroxy-2'-phenyl)ethyl-1,3-dioxolane 
• 55337-55-8 2-(2-oxo-2-phenyl-ethyl)-1,3-dioxolane 

Relevant academic research and scientific papers

Simple and high yielding syntheses of β-keto esters catalysed by zeolites

Simple and high yielding syntheses of several β-keto esters, catalysed by zeolite Hβ are reported. The methods developed include condensation of aldehydes with ethyl diazoacetate and transesterification of β-keto esters with primary, secondary, allylic and benzylic alcohols etc., all catalysed by Hβ. It was further observed that under microwave irradiation the yields of many aromatic β-keto esters were enhanced appreciably.

Acylketene acetals in organic synthesis

The preparation and reactivity of achiral and enantiomerically pure acylketene acetals are described. The key reactions of these substrates involve facile conjugate hydroboration and organolithium addition. Enantiomerically pure acylketene acetals were employed to generate a homochiral β-keto ketal through a highly diastereoselective lithium enolate quench. This β-ketal, which was also prepared through a desymmetrization ketalization reaction on a meso dione, was employed in the synthesis of the insect pheromone sitophilure.