1360952-35-7 Usage
General Description
Methyl 6-chloro-5-(trifluoromethyl)nicotinate is a chemical compound that belongs to the family of nicotinic acid derivatives. It is a white crystalline solid with a molecular formula of C9H6ClF3NO2. Methyl 6-chloro-5-(trifluoroMethyl)nicotinate is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various drugs and pharmaceutical products. It has also been studied for its potential pharmacological properties, including its role as an anti-inflammatory and antifungal agent. Additionally, it can be used as a building block in the synthesis of other organic compounds due to its versatile reactivity and functional groups.
Check Digit Verification of cas no
The CAS Registry Mumber 1360952-35-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,0,9,5 and 2 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1360952-35:
(9*1)+(8*3)+(7*6)+(6*0)+(5*9)+(4*5)+(3*2)+(2*3)+(1*5)=157
157 % 10 = 7
So 1360952-35-7 is a valid CAS Registry Number.
1360952-35-7Relevant articles and documents
Development of a safe and economical synthesis of methyl 6-chloro-5-(trifluoromethyl)nicotinate: Trifluoromethylation on kilogram scale
Mulder, Jason A.,Frutos, Rogelio P.,Patel, Nitinchandra D.,Qu, Bo,Sun, Xiufeng,Tampone, Thomas G.,Gao, Joe,Sarvestani, Max,Eriksson, Magnus C.,Haddad, Nizar,Shen, Sherry,Song, Jinhua J.,Senanayake, Chris H.
, p. 940 - 945 (2013)
Reported herein is a safe and economical synthesis of methyl 6-chloro-5-(trifluoromethyl)nicotinate, an intermediate in the synthesis of novel anti-infective agents. The key to this process is the trifluoromethylation of an aryl iodide using an inexpensive methyl chlorodifluoroacetate (MCDFA)/KF/CuI system, with an emphasis on the development work which led to this effective process.