13732-26-8

Usage

Uses

Used in Organic Synthesis:
2-(Phenylhydrazono)malonic acid dimethyl ester is used as a reagent for the synthesis of heterocyclic compounds, which are essential in various chemical and pharmaceutical applications. Its phenylhydrazine functional group enables it to undergo a range of chemical reactions, making it a valuable component in the creation of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-(Phenylhydrazono)malonic acid dimethyl ester is utilized as a building block for the development of new drugs and medicinal compounds. Its ability to participate in various chemical reactions allows for the synthesis of diverse and effective pharmaceutical agents.
Used in Chemical Research:
2-(Phenylhydrazono)malonic acid dimethyl ester is also employed in chemical research for studying the properties and reactions of malonic acid derivatives and phenylhydrazine-containing compounds. This helps in advancing the understanding of organic chemistry and contributes to the discovery of new chemical processes and applications.

InChI:InChI=1/C11H12N2O4/c1-16-10(14)9(11(15)17-2)13-12-8-6-4-3-5-7-8/h3-7,12H,1-2H3

Upstream product

• 186581-53-3 diazomethane 
• 136966-69-3 phenylhydrazono-malonic acid monomethyl ester 
• 3298-40-6 mesoxalate de methyle 
• 100-63-0 phenylhydrazine 
• 40885-82-3 2-(phenylhydrazono)malonic acid 
• 2684-02-8 benzenediazonium 
• 64-17-5 ethanol 
• 127-09-3 sodium acetate 
• 108-59-8 malonic acid dimethyl ester 
• 67-56-1 methanol 
• 6134-59-4 diethyl 2-(phenylhydrazono)malonate 
• 142-04-1 aniline hydrochloride 
• 100-34-5 benzene diazonium chloride 

Downstream Products

• 40885-79-8 phenylhydrazono-malonic acid monoethyl ester 
• 136966-69-3 phenylhydrazono-malonic acid monomethyl ester 
• 40885-82-3 2-(phenylhydrazono)malonic acid 
• 50599-22-9 phenylhydrazono-malonic acid diamide 
• 107111-24-0 phenylhydrazono-malonic acid bis-methylamide 
• 75872-34-3 1,6-Dihydro-4-methoxy-1-phenyl-6-(phenylimino)-3-pyridazincarbonsaeure-methylester 
• 75872-33-2 1,6-Dihydro-4-methoxy-6-oxo-1-phenyl-3-pyridazincarbonsaeure-methylester 
• 75872-34-3 4-Methoxy-1-phenyl-6-[(E)-phenylimino]-1,6-dihydro-pyridazine-3-carboxylic acid methyl ester 
• 76368-96-2 dimethyl 2-(p-nitrophenylhydrazono)propanodioate 
• 56840-65-4 dimethyl 2-(o-nitrophenylhydrazono)propanedioate 
• 53792-98-6 KP-23202 

Relevant academic research and scientific papers

Solid phase synthesis of 6-acylamino-1-alkyl/aryl-4-oxo-1,4- dihydrocinnoline-3-carboxamides

6-Acylmino-1-alkyl/aryl-4-oxo-1,4-dihydrocinnoline-3-carboxamides were synthesized in parallel from 6-nitro-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid. The latter formed amides with amines bound to polystyrene-based resins via acid-labile linkers. N1 an

Synthesis, spectral and structural studies, and an evaluation of the hydrogen bonding of some phenylhydrazones

A series of 46 phenylhydrazones, some novel, containing a variety of structural types has been synthesised. These have been studied by 1H n.m.r. and i.r. spectroscopy with respect to potential inter- and intra-molecular hydrogen bonding. ortho-Nitro or -carbonyl groups form strong hydrogen bonds to the imino-group which are readily observed by 1H n.m.r. but not by i.r. spectroscopy. 'Terminal' carbonyl groups also form strong hydrogen bonds to the imino-group and these can be detected by both i.r. and 1H n.m.r. spectroscopy. When both ortho-nitro- or -carbonyl groups and 'terminal' carbonyl groups are present the imino hydrogen atom is doubly hydrogen bonded and this is apparent in the 1H n.m.r. spectrum. The formation of an intramolecular hydrogen bond in the phenylhydrazone prevents the formation of an intermolecular hydrogen bond between the phenylhydrazone and a polar solvent.