141377-56-2Relevant academic research and scientific papers
Water-assisted organocatalysis: An enantioselective green protocol for the henry reaction
Thorat, Prashant B.,Goswami, Santosh V.,Jadhav, Wamanrao N.,Bhusare, Sudhakar R.
, p. 661 - 666 (2013)
We report an enantioselective Henry (nitroaldol) reaction catalysed by an organocatalyst using water as solvent. The enantioselective synthesis of β-nitroalcohols was achieved by using a neutral chiral organocatalyst, through strong hydrogen bonding, whic
Asymmetric Henry reaction of aldehydes catalyzed by recyclable an MCM-41 supported copper(II) salen complex
Dhahagani, Karuthamohamed,Rajesh, Jegathalaprathaban,Kannan, Ramanujam,Rajagopal, Gurusamy
, p. 857 - 865 (2011)
A chiral modified MCM-41-Cu(salen) complex has been prepared and characterized by SEM, powder XRD, and EDX techniques as well as FT-IR and EPR spectroscopic methods. This new catalytic system was examined in the asymmetric Henry reaction between various a
Enantioselective hydroxylation of nitroalkenes: An organocatalytic approach
Diner, Peter,Nielsen, Martin,Bertelsen, Soren,Niess, Barbara,Jorgensen, Karl Anker
, p. 3646 - 3648 (2007)
An easy hydroxylation of aliphatic nitroalkenes in high yields and enantioselectivities is catalysed by bifunctional thiourea-cinchona alkaloids giving access to optically active nitroalcohols and aminoalcohols as final products. The Royal Society of Chem
Enantioselective catalysts for the Henry reaction: Fine-tuning the catalytic components
Constable, Edwin C.,Zhang, Guoqi,Housecroft, Catherine E.,Neuburger, Markus,Schaffner, Silvia,Woggon, Wolf-D.,Zampese, Jennifer A.
, p. 2166 - 2173 (2009)
Catalysts for the asymmetric Henry reaction involving 1,6-bis(3-ethoxy-2- hydroxyphenyl)-(3S,4S)-(-)-diphenyl-2,5-diazahexane (H22) and copper salts have been investigated. Conditions for the conversion of 4-nitrobenzaldehyde to 2-nitro-1-(4-ni
Enantioselective nitroaldol (Henry) reaction using copper(II) complexes of (-)-sparteine
Maheswaran,Prasanth, K. Leon,Krishna, G. Gopi,Ravikumar,Sridhar,Kantam, M. Lakshmi
, p. 4066 - 4068 (2006)
The dichloro[(-)-sparteine-N,N′]copper(ii) complex provides Henry adducts with high enantioselectivities (73-97% ee) in Henry reaction between nitromethane and various aldehydes. The Royal Society of Chemistry 2006.
Efficient and recyclable catalysts based on simple chiral N 1-alkyl, N2-arylmethyl diamines in the Cu-catalyzed asymmetric Henry reactions
Liu, Fei,Gou, Shaohua,Li, Lei,Yan, Peisheng,Zhao, Chunhong
, p. 163 - 168 (2013)
A class of (1R,2R)-N1-alkyl, N2-(4-chlorobenzyl) cyclohexane-1,2-diamines (4) were designed and synthesized. They were used to form the corresponding copper(II) complexes, 4-Cu(OAc)2, as chiral catalysts in the asymmetric
Solvent-dependent strong asymmetric amplification in the catalytic enantioselective Henry reaction using the trans-N,N′-bis-biphenyl-4-ylmethyl-cyclohexane-1,2-diamine-CuCl2 complex
Tanaka, Koichi,Iwashita, Tomoharu,Yoshida, Erika,Ishikawa, Tomomi,Otuka, Shinya,Urbanczyk-Lipkowska, Zofia,Takahashi, Hiroki
, p. 7907 - 7910 (2015)
A strong asymmetric amplification was observed in the enantioselective Henry reaction catalyzed by the (R,R)-trans-N,N′-bis-biphenyl-4-ylmethyl-cyclohexane-1,2-diamine·CuCl2 complex in AcOEt, while no amplification occurred in MeOH.
Optimization of privileged structures for selective and potent melanocortin subtype-4 receptor ligands
Hong, Qingmei,Bakshi, Raman K.,Dellureficio, James,He, Shuwen,Ye, Zhixiong,Dobbelaar, Peter H.,Sebhat, Iyassu K.,Guo, Liangqin,Liu, Jian,Jian, Tianying,Tang, Rui,Kalyani, Rubana N.,MacNeil, Tanya,Vongs, Aurawan,Rosenblum, Charles I.,Weinberg, David H.,Peng, Qingping,Tamvakopoulos, Constantin,Miller, Randy R.,Stearns, Ralph A.,Cashen, Doreen,Martin, Willian J.,Chen, Airu S.,Metzger, Joseph M.,Chen, Howard Y.,Strack, Allison M.,Fong, Tung M.,MacLntyre, Euan,Van Der Ploeg, Lex H.T.,Wyvratt, Matthew J.,Nargund, Ravi P.
, p. 4483 - 4486 (2010)
Design, syntheses and structure-activity relationships of N-acetylated piperazine privileged structures containing MC4R agonist compounds were described. The most potent derivatives were low nM MC4R selective full agonists. Several compounds from the series had modest pharmacokinetic properties.
Catalytic Asymmetric Nitroaldol Reactions. A New Practical Method for the Preparation of the Optically Active Lanthanum Complex
Sasai, Hiroaki,Suzuki, Takeyuki,Itoh, Noriie,Shibasaki, Masakatsu
, p. 851 - 854 (1993)
The optically active La complex, which catalyzes asymmetric nitroaldol reactions, was found to be readily prepared from LaCl3*7H2O.The presence of water, LiCl or LiBr and an alkali metal hydroxide was essential for the formation of the effective lanthanum
Recoverable salen-based macrocyclic chiral complexes; Catalysts for enantioselective Henry reactions
Ibrahim, Farah,Jaber, Nada,Guerineau, Vincent,Hachem, Ali,Ibrahim, Ghassan,Mellah, Mohamed,Schulz, Emmanuelle
, p. 1395 - 1401 (2013)
Cobalt and chromium complexes have been prepared from chiral calix-salen cyclic ligands. The corresponding tetrahydrosalen reduced forms have been used for copper salt complexation. These new chiral catalysts have been tested for their ability to promote
