3:;14435-92-8Relevant articles and documents
The exciting chemistry of tetraazidomethane
Banert, Klaus,Joo, Young-Hyuk,Rueffer, Tobias,Walfort, Bernhard,Lang, Heinrich
, p. 1168 - 1171 (2007)
(Chemical Equation Presented) With a nitrogen content of 93.3%, "perazidomethane(CN12) is highly explosive but nevertheless isolable. The title compound, which is accessible from commercially available trichloroacetonitrile in one step, undergo
Carbonyl diazide, OC(N3)2: Synthesis, purification, and IR spectrum
Nolan, Alex M.,Amberger, Brent K.,Esselman, Brian J.,Thimmakondu, Venkatesan S.,Stanton, John F.,Woods, R. Claude,McMahon, Robert J.
, p. 9846 - 9851 (2012)
Carbonyl diazide (1), OC(N3)2, is prepared by reaction of triphosgene and tetra-n-butylammonium azide in a solution of diethyl ether or dimethyl ether. The advantage of this synthetic method, relative to other procedures, is that the use of triphosgene, OC(OCCl3) 2, mitigates the need to use highly poisonous reagents such as phosgene, OCCl2, or chlorofluorocarbonyl, OC(Cl)F. The identity and purity of OC(N3)2 are established by gas-phase IR spectroscopy, which reveals the presence of both syn-syn and anti-syn conformers. Computed anharmonic vibrational frequencies and infrared intensities of carbonyl diazide (1) display excellent agreement with experiment, and reveal the presence of strong Fermi resonances.
Fascinating diazirinone: A violet gas
Zeng, Xiaoqing,Beckers, Helmut,Willner, Helge,Stanton, John F.
, p. 3403 - 3409 (2012)
Diazirinone (cyclic N2CO) recently identified in solid noble gas matrices and in the gas phase by infrared spectroscopy, has now been trapped at -196°C as a neat brownish-yellow solid, and characterized by low-temperature IR and Raman spectroscopy. Evaporation of the solid yields violet gaseous N2CO, which is surprisingly stable in a clean quartz cell. Its decay at room temperature in the dark follows a second-order rate law (k2 = 4.9 × 10-2 L mol-1 s-1) with a half-life of 30 h at an initial pressure of 5 mbar. The visible absorption spectrum of the gas reveals a structured band with the 0-0 transition at 567 nm (17651 cm-1), and its assignment has been made with the aid of theoretical calculations. Cyclic diazirinone that is isolated in solid Ar at 16 K decomposes upon visible light irradiation to yield N2 and CO, but after being exposed to ArF excimer laser irradiation (193 nm) the N=N bond is cleaved and the open-chain isomers NOCN, ONCN, and ONNC are formed. Diazirinone (cyclic N2CO) has been prepared in a neat form as a violet gas. It has a half-life of 30 h at an initial pressure of 5 mbar in a clean quartz container at room temperature, and the substance has been characterized by IR, Raman, and UV/Vis spectroscopy. Copyright
Matrix isolation of two isomers of N4CO
Zeng, Xiaoqing,Beckers, Helmut,Willner, Helge
, p. 482 - 485 (2011)
A close analogue to diazide: Azido isocyanate, N3-NCO, is formed by a stepwise photo-induced decomposition of carbonyl diazide, CO(N 3)2, and characterized by matrix IR, UV/Vis spectroscopy, and DFT calculations (see scheme). The azido carbonyl nitrene intermediate N3C(O)N has also been characterized.
Asymmetric Radical Bicyclization of Allyl Azidoformates via Cobalt(II)-Based Metalloradical Catalysis
Jiang, Huiling,Lang, Kai,Lu, Hongjian,Wojtas, Lukasz,Zhang, X. Peter
supporting information, p. 9164 - 9167 (2017/07/22)
Cobalt(II)-based metalloradical catalysis has been successfully applied to radical bicyclization of allyl azidoformates to construct aziridine/oxazolidinone-fused bicyclic structures. The Co(II) complex of D2-symmetric chiral amidoporphyrin 3,5
Hydantoins and related heterocycles as inhibitors of matrix metalloproteinases and/or TNF-alpha converting enzyme (TACE)
-
, (2008/06/13)
The present application describes novel hydantoin derivatives of formula (I): or pharmaceutically acceptable salt or prodrug forms thereof, wherein A, B, R1, R2, R3, R4, R5, R6, R7, R11, and n are defined in the present specification, which are useful as inhibitors of matrix metalloproteinases (MMP), TNF-α converting enzyme (TACE), aggrecanase, or a combination thereof.
