2835-98-5

Basic information

• Product Name: 6-Amino-m-cresol
• Synonyms: JAROCOL 2M5AP;6-amino-meta-cresol;6-Amino-m-cresol;2-Amino-5-methylphenol;2-AMINO-5-METHYLPHENOL 98%;6-Amino-m-methylphenol;m-Hydroxy-p-toluidine;Phenol, 2-amino-5-methyl-;6-AMINO-M- CRESOL, 4-AMINO- 3- HYDROXYTOLUENE, 2-AMINO-5- METHYLPHENOL, 2- HYDROXY-4- METHYLANILINE
• CAS NO: 2835-98-5
• Molecular Formula: C₇H₉NO
• Molecular Weight: 123.15
• EINECS: 220-618-6
• Product Categories: Aromatic Phenols;Phenoles and thiophenoles;Amines;NULL
• Mol File: 2835-98-5.mol
• Article Data: 14

Chemical Properties

• Melting Point: 160-162 °C(lit.)
• Boiling Point: 229.26°C (rough estimate)
• Flash Point: 99.8 °C
• Appearance: Beige to brown crystal powder
• Density: 1.0877 (rough estimate)
• Refractive Index: 1.5380 (estimate)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 9.87±0.10(Predicted)
• Water Solubility: soluble
• Stability: Hygroscopic
• BRN: 386144
• CAS DataBase Reference: 6-Amino-m-cresol(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Amino-m-cresol(2835-98-5)
• EPA Substance Registry System: 6-Amino-m-cresol(2835-98-5)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 26-36-37/39
• WGK Germany: 1
• RTECS: SJ6090000
• Hazardous Substances Data: 2835-98-5(Hazardous Substances Data)

Usage

Chemical Properties

Beige to brown crystal powder

Uses

2-Amino-5-methylphenol was used in the synthesis of tridentate Schiff base ligand and novel non-metallocene catalysts with phenoxy-imine ligands.

General Description

2-Amino-5-methylphenol reacts with bovine hemoglobin to form 2-amino-4,4α-dihydro-4α-7-dimethyl-3H-phenoxazine-3-one, which inhibits the proliferation of Poliovirus in Vero cells. It is converted to dihydrophenoxazinone by purified human hemoglobin.

Purification Methods

Crystallise it from H2O, 50% EtOH, or toluene. [Beilstein

InChI:InChI=1/C7H9NO/c1-5-2-3-6(8)7(9)4-5/h2-4,9H,8H2,1H3

Upstream product

• 2101-86-2 p-methylazidobenzene 
• 700-38-9 2-nitro-5-methylphenol 
• 88-44-8 2-Amino-5-methylbenzenesulfonic acid 
• 452-86-8 4-methyl-1,2-dihydroxybenzene 
• 64-17-5 ethanol 
• 861619-98-9 2-amino-3-bromo-5-methyl-phenol 
• 64-19-7 acetic acid 
• 7647-01-0 hydrogenchloride 
• 35605-65-3 4-Methyl-2-hydroxyphenylazoformamid 
• 196497-20-8 (1R,5S,8R)-8-methoxy-3,3-dimethyl-2,4,7-trioxabicyclo[3.3.0]octan-6-one 
• 100-46-9 benzylamine 
• 74993-52-5 O-(3-methylphenyl)hydroxylamine 

Downstream Products

• 117099-26-0 N-(2-hydroxy-4-methylphenyl)furan-2-carboxamide 
• 13429-10-2 N-(2-hydroxy-4-methylphenyl)acetamide 
• 106421-35-6 5-(2-hydroxy-4-methyl-phenylcarbamoyl)-benzene-1,3-disulfonyl chloride 
• 55697-67-1 2-(4-tert-pentyl-phenoxy)-butyric acid-(2-hydroxy-4-methyl-anilide) 
• 62143-66-2 1-benzoylamino-2-benzoyloxy-4-methyl-benzene 
• 103854-30-4 butyric acid-(2-hydroxy-4-methyl-anilide) 
• 854625-32-4 2-(2,4-dinitro-phenoxy)-4-methyl-aniline 
• 301325-96-2 2-(2,4-dinitro-anilino)-5-methyl-phenol 
• 14847-51-9 2-bromo-5-methylphenol 
• 35928-80-4 6-iodo-3-methyl-phenol 
• 98922-98-6 2'-hydroxy-2,2,4'-trimethylpropionanilide 
• 23417-29-0 6-methylbenzo[d]oxazole-2-thiol 

Relevant articles and documents

High-Density and Thermally Stable Palladium Single-Atom Catalysts for Chemoselective Hydrogenations

Single-atom catalysts (SACs) have shown superior activity and/or selectivity for many energy- and environment-related reactions, but their stability at high site density and under reducing atmosphere remains unresolved. Herein, we elucidate the intrinsic driving force of a Pd single atom with high site density (up to 5 wt %) under reducing atmosphere, and its unique catalytic performance for hydrogenation reactions. In situ experiments and calculations reveal that Pd atoms tend to migrate into the surface vacancy-enriched MoC surface during the carburization process by transferring oxide crystals to carbide crystals, leading to the surface enrichment of atomic Pd instead of formation of particles. The Pd1/α-MoC catalyst exhibits high activity and excellent selectivity for liquid-phase hydrogenation of substituted nitroaromatics (>99 %) and gas-phase hydrogenation of CO2 to CO (>98 %). The Pd1/α-MoC catalyst could endure up to 400 °C without any observable aggregation of single atoms.

Ramoplanin derivatives possessing antibacterial activity

Novel ramoplanin derivatives are disclosed. These ramoplanin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against gram positive bacteria, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.

Indium Mediated Reduction of Nitro and Azide Groups in the Presence of HCl in Aqueous Media

Indium mediated reduction of azide and nitro groups in the presence of HCl (1.5 equiv based on indium) at room temperature in aqueous THF successfully provided the corresponding amine in high to quantitative yields. Under the some reaction conditions, selective reduction of azide and nitro group in the presence of vinyl group could be accomplished.