14970-83-3

Usage

Uses

Used in Electronics Industry:
4-MERCAPTO-1-BUTANOL is used as a capping agent for the synthesis of metal nanoparticles, such as Highly Concentrated Nano-Au and Nano-Ag "Inks". The hydrophilic sparse ionic monolayer formed by 4-MERCAPTO-1-BUTANOL protects the metal nanoparticles, allowing them to be sintered at relatively low temperatures (150 °C) to achieve near-bulk conductivity. This application is particularly useful in the development of conductive inks for printed electronics and other related applications.
Used in Chemical Synthesis:
4-MERCAPTO-1-BUTANOL can be used as a reagent in various chemical synthesis processes due to its reactive thiol group. It can be employed in the production of various organic compounds, including pharmaceuticals, agrochemicals, and specialty chemicals, where its unique properties can be exploited to facilitate specific reactions or improve product yields.
Used in Analytical Chemistry:
The thiol group in 4-MERCAPTO-1-BUTANOL makes it a useful compound for the detection and quantification of heavy metals, such as mercury, lead, and cadmium, through techniques like atomic absorption spectroscopy (AAS) or inductively coupled plasma mass spectrometry (ICP-MS). The strong affinity of the thiol group for heavy metals allows for selective complexation and subsequent detection or separation of these toxic elements from various samples.
Used in Cosmetics and Personal Care Industry:
4-MERCAPTO-1-BUTANOL can be used as a preservative in the cosmetics and personal care industry. Its antimicrobial properties help to prevent the growth of bacteria, fungi, and other microorganisms in products like lotions, creams, and shampoos, thereby extending their shelf life and ensuring product safety.

InChI:InChI=1/C4H10OS/c5-3-1-2-4-6/h5-6H,1-4H2

Upstream product

• 928-51-8 4-Chloro-1-butanol 
• 1003-10-7 Thiobutyrolactone 
• 110-63-4 Butane-1,4-diol 
• 6972-09-4 4-methylbenzenesulfonic acid, 4-hydroxybutyl ester 
• 42729-95-3 4-hydroxybutyl methanesulfonate 
• 15018-33-4 2-(ω-bromobutylthio)-4,6-dimethylpyrimidine 
• 4753-59-7 4-Bromobutyl acetate 
• 17356-08-0 thiourea 
• 33036-62-3 4-Bromo-1-butanol 
• 109-99-9 tetrahydrofuran 
• 92351-81-0 4-acetylthio-1-butyl acetate 

Downstream Products

• 113314-29-7 1-phenylcarbamoylsulfanyl-4-phenylcarbamoyloxy-butane 
• 857894-89-4 (Z)-S-(4-hydroxybutyl) phenylacetothiohydroximate 
• 500547-34-2 5-[2-[(4-hydroxybutyl)thio]-2-(thien-3-yl)ethyl]-2-methyl-2-phenylfuran-3(2H)-one 
• 1006391-71-4 4-[2-(4-bromophenyl)ethyl]-1,4-thiazaperhydroocin-3-one 
• 1343471-92-0 C₁₁H₁₄O₂S₂ 
• 1343471-94-2 C₁₀H₁₃ClOS₂ 
• 1343471-97-5 C₁₀H₁₃BrOS₂ 
• 1343471-95-3 C₁₁H₁₆O₂S₂ 
• 1343471-79-3 C₁₀H₁₃BrOS₂ 
• 1343471-93-1 C₁₀H₁₃ClOS₂ 
• 1377765-78-0 4-mercaptobutyl 3-O-acetyl-2,4,6-tri-O-benzyl-β-D-galactopyranosyl-(1->)-2,3,6-tri-O-benzyl-β-D-glucopyranoside 
• 1377765-44-0 4-mercaptobutyl 2,3,4,6-tetra-O-benzyl-β-D-glucopyranoside 
• 1377766-01-2 4-mercaptobutyl 4-O-allyl-2-azido-3,6-di-O-benzyl-2-deoxy-β-D-glucopyranoside 
• 1377765-98-4 4-mercaptobutyl 4-O-allyl-2-azido-3,6-di-O-benzyl-2-deoxy-α-D-glucopyranoside 

Relevant academic research and scientific papers

Alkyl ether sulfonyl fluoride compound and synthesis method thereof

The invention provides an alkyl ether sulfonyl fluoride compound and a synthesis method thereof. The method comprises the steps that an alkyl dihydric alcohol compound is taken as a start, firstly, sulfhydrylation is carried out so as to obtain a sulfhydryl compound containing monohydric alcohol; and the sulfhydryl compound reacts with halogenated alkane so as to obtain a sulfydryl-containing ether compound; the sulfydryl-containing ether compound is subjected to the action of thionyl chloride and alkali so as to obtain alkyl ether sodium sulfonate; and the alkyl ether sodium sulfonate is prepared into the alkyl ether sulfonyl fluoride compound under a fluorinating reagent. The alkyl ether sulfonyl fluoride compound can serve as a perfluoroalkyl substance precursor, and electrofluorinationis carried out so as to prepare a corresponding perfluoroalkyl substance. The alkyl ether sulfonyl fluoride compound has the advantages that different carbon chain numbers at the two ends of an etherchain compound can be provided, objective data can be provided for basic research, the compound can serve as a novel perfluoroalkyl ether compound precursor, a synthesis process is simple, raw materials are easy to obtain, and the method has relatively good atom economy and strong applicability.

A 4 - mercapto -1 - butanol synthesis process

The present invention discloses a 4-mercapto-1-butanol synthesis process, which comprises: 1) dissolving 1,4-butanediol and an acid-binding agent in an organic solvent I, adding a sulfonylation agent in a dropwise manner to carry out a sulfonylation reaction, carrying out extraction separation with dichloromethane, and carrying out washing, drying and concentration to obtain a colorless oil-like substance; and 2) dissolving the colorless oil-like substance obtained in the step 1) in an organic solvent II, adding a nucleophile to carry out a nucleophilic substitution reaction, and finally carrying out pressure reducing distillation to obtain the 4-mercapto-1-butanol. According to the present invention, the completely-new 4-mercapto-1-butanol synthesis route is provided, the used raw materials are easy to obtain, the operation is simple, the reaction conditions are not harsh, and good industrial values are provided.

Sulfoboration of Cyclic Ethers - A Preparative Route to Mercaptoalkanols and Bis(hydroxyalkyl) Sulfides

Bis(1,5-cyclooctanediylboryl) sulfide (1) reacts slowly with the cyclic ethers A-D to give O,S-bis(9-BBN)mercaptoalkanols 2a-d in excellent yields.From oxetane (E) and 1, however, 2e is obtained rapidly, which further reacts with E to yield the bis(9-BBN-oxypropyl) sulfide 3ee. 2a and c react with E to form the mixed thioethers 3ae and 3ce, respectively.The methanolysis of 2a-e leads to the O-(9-BBN)mercaptoalkanols 4a-e.The compounds 2 and 3 react with acetylacetone or with 2-aminoethanol to yield the mercaptoalkanols 7a-c, e and the bis(hydroxyalkyl) sulfides 8ae, 8ce and 8ee, resp., in high yields beside the 9-BBN-chelates 5 or 6.Key Words: Ethers, cyclic, cleavage of / Sulfoborations / Mercaptoethanols, 9-BBN derivatives of / Sulfides, bis(hydroxyalkyl), 9-BBN derivatives of

THE CHEMISTRY OF α,ω-MERCAPTOALCOHOLS IN THE PRESENCE OF DIETHOXYTRIPHENYLPHOSPHORANE. TEMEPERATURE DEPENDENCE OF CYCLODEHYDRATIONS AND S-ETHYLATIONS

Diethoxytriphenylphosphorane (DTPP) is easily prepared by oxidative addition of triphenylphosphine with diethyl peroxide.DTPP converts a variety of mercaptoalcohols to cyclic sulfides as well as hydroxythioethers.The temperature dependence (+25 --> -25 deg C) of the product distribution has synthetic petential.

ACTIVITY OF 1-OXA-3-THIACYCLOALKANES AND 2-ALKYLTHIOOXACYCLANES IN FREE-RADICAL ISOMERIZATION

It was established that radical isomerization to alkyl esters of thiocarboxylic acids, initiated by tert-butyl peroxide at 130-150 deg C, is a common reaction for five-, six- and seven-membered 1-oxa-3-thiacycloalkanes and 2-alkylthiooxacycloalkanes.Under analogous conditions 2-diethylaminotetrahydropyran isomerizes to N,N-diethylvaleramide.The relation between the structure and the reactivity of 1-oxa-3-thiacycloalkanes and 2-alkylthiooxacycloalkanes in free-radical isomerisation was studied by the method of competing reactions.Depending on the ring size, the activity of the 1-oxa-3-thiacycloalkanes increases in the order : 1,3-oxathianes 1,3-oxathiolanes 1,3-oxathiepanes.