15182-06-6

Usage

Uses

Used in Pharmaceutical Industry:
2-[2-(Dimethylamino)ethoxy]benzaldehyde 97 is used as an intermediate compound for the synthesis of various pharmaceutical products. Its unique structure allows it to be a key component in the development of new drugs, potentially contributing to the treatment of various medical conditions.
Used in Chemical Research:
In the field of chemical research, 2-[2-(Dimethylamino)ethoxy]benzaldehyde 97 serves as a valuable compound for studying the properties and reactions of complex organic molecules. Its presence in various chemical reactions can provide insights into the behavior of similar compounds and contribute to the advancement of chemical knowledge.
Used in Material Science:
2-[2-(Dimethylamino)ethoxy]benzaldehyde 97 can be utilized in the development of new materials with specific properties. Its incorporation into polymers or other materials can lead to the creation of novel substances with unique characteristics, such as improved stability, reactivity, or other desirable traits.
Used in Flavor and Fragrance Industry:
Due to its aromatic nature, 2-[2-(Dimethylamino)ethoxy]benzaldehyde 97 can be used as a component in the creation of fragrances and flavors. Its distinctive scent profile can contribute to the development of new and innovative products in the fragrance and flavor industry.

InChI:InChI=1/C11H15NO2/c1-12(2)7-8-14-11-6-4-3-5-10(11)9-13/h3-6,9H,7-8H2,1-2H3

Upstream product

• 90-02-8 salicylaldehyde 
• 107-99-3 2-(dimethylamino)ethyl chloride 
• 13468-02-5 dimethyl(2-phenoxyethyl)amine 
• 68-12-2 N,N-dimethyl-formamide 
• 124-40-3 dimethyl amine 
• 106-93-4 ethylene dibromide 
• 6052-79-5 2-(2-hydroxyphenyl)-1,3-dioxane 
• 1391906-41-4 2-(dimethylamino)ethyl ethyl carbonate 
• 54373-14-7 2-(2-chloroethoxy)benzoic aldehyde 
• 4584-46-7 (2-chloroethyl)dimethylamine hydrochloride 
• 108-95-2 phenol 

Downstream Products

• 91215-97-3 2-(2-dimethylamino-ethoxy)-benzylamine 
• 88159-72-2 (E)-3-[2-(2-Dimethylamino-ethoxy)-phenyl]-2-thiophen-2-yl-acrylonitrile; hydrochloride 
• 88136-98-5 (Z)-3-[2-(2-Dimethylamino-ethoxy)-phenyl]-2-(1H-indol-3-yl)-acrylonitrile 
• 114896-52-5 1-(2-(2-dimethylaminoethoxy)phenyl)-2,3,4,9-tetrahydro-1H-pyrido<3,4-b>indole hydrochloride 
• 86759-05-9 [4-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-piperazin-1-yl]-[1-[2-(2-dimethylamino-ethoxy)-phenyl]-meth-(E)-ylidene]-amine 
• 84203-09-8 2-(2-(4,5-diphenyl-1H-imidazol-2-yl)phenoxy)-N,N-dimethylethanamine 
• 1301625-97-7 C₁₆H₂₇N₃O 
• 1301625-95-5 C₁₅H₂₅N₃O 
• 112562-93-3 2-[2-(2-Dimethylamino-ethoxy)-phenyl]-thiazolidine-3-carbothioic acid methylamide; hydrochloride 
• 86759-03-7 [4-(10,11-Dihydro-dibenzo[b,f]thiepin-10-yl)-piperazin-1-yl]-[1-[2-(2-dimethylamino-ethoxy)-phenyl]-meth-(E)-ylidene]-amine 

Relevant academic research and scientific papers

Mustard Carbonate Analogues as Sustainable Reagents for the Aminoalkylation of Phenols

N,N-dialkyl ethylamine moiety can be found in numerous scaffolds of macromolecules, catalysts, and especially pharmaceuticals. Common synthetic procedures for its incorporation in a substrate relies on the use of a nitrogen mustard gas or on multistep syntheses featuring chlorine hazardous/toxic chemistry. Reported herein is a one-pot synthetic approach for the easy introduction of aminoalkyl chain into different phenolic substrates through dialkyl carbonate (β-aminocarbonate) chemistry. This new direct alcohol substitution avoids the use of chlorine chemistry, and it is efficient on numerous pharmacophore scaffolds with good to quantitative yield. The cytotoxicity via MTT of the β-aminocarbonate, key intermediate of this synthetic approach, was also evaluated and compared with its alcohol precursor.

Urea-Zinc Chloride Eutectic Mixture-Mediated One-Pot Synthesis of Imidazoles: Efficient and Ecofriendly Access to Trifenagrel

The low-melting mixture urea-ZnCl 2 was evaluated as a novel reaction medium for the synthesis of imidazoles. The reaction between a dicarbonyl compound, ammonium acetate, and an aromatic aldehyde is efficiently catalyzed by the eutectic solvent, yielding a wide variety of triaryl-1 H -imidazoles or 2-aryl-1 H -phenanthro[9,10- d ]imidazoles in good to excellent yields. In addition, the eutectic solvent was reused in five cycles without loss of its catalytic activity. This protocol was further explored for the synthesis of the drug trifenagrel, giving an excellent yield.

Synthesis, cytotoxicity and topoisomerase inhibition properties of multifarious aminoalkylated indeno[1,2-c]isoquinolin-5,11-diones

A number of mono- or diaminoalkylated indeno[1,2-c]isoquinolin-5,11-diones analogs of 1 were synthesized and evaluated for their DNA binding affinities, topoisomerase inhibition properties and antiproliferative activities against human cancer cell lines (

Room temperature synthesis of tri-, tetrasubstituted imidazoles and bis-analogues by mercaptopropylsilica (MPS) in aqueous methanol: application to the synthesis of the drug trifenagrel

The heterogeneous solid catalyst, mercaptopropylsilica (MPS), has been prepared by a modified procedure in water and its structure confirmed by solid state carbon-13 CP-MAS NMR spectrum. This catalyst has been efficiently utilized for the synthesis of a w

Diphenyl-substituted heterocycles, processes for preparing them and their use as pharmaceutical compositions

The invention relates to new diphenyl-substituted 5-ring heterocycles of general formula (I) wherein A, X and the groups R1, R2, R3, R4and R5are defined as in the claims, processes for preparing them

ortho-Directed Lithiation of (2-Methoxy)ethoxy- and (2-Dimethylamino)ethoxy-arenes

ortho-Directed lithiation of a number of (2-methoxy)ethoxy- and (2-dimethylamino)ethoxy-arenes has been investigated.Lithiation of these compounds followed by treatment with various electrophiles afforded ortho-substituted products in moderate to excellent yields.Keywords-ortho-directed lithiation; (2-methoxy)ethoxyarene; (2-dimethylamino)ethoxyarene; regioselectivity