15344-34-0Relevant articles and documents
Studies on phosphoroheterocycle chemistry III: An unusual way to 1,3,2-thiazaphospholidine-4-thione 2-sulfide derivatives
Deng, ShengLou,Chen, RuYu
, p. 2527 - 2531 (2002)
An unusual but efficient method for the synthesis of phosphoroheterocycles, 1,3,2-thiazaphospholidine-4-thione 2-sulfide derivatives, by the reaction of Lawesson's reagent with a variety of α-hydroxy nitriles has been developed. The possible mechanism of the reaction is proposed to involve thiation of hydroxy group in a first step, sequential addition of P-SH to the nitrile and rearrangement resulting in the title phosphoroheterocycles. The preliminary bioassays show that these heterocyclic compounds have herbicidal properties.
Direct C(sp3)-H Cyanation Enabled by a Highly Active Decatungstate Photocatalyst
Kim, Kunsoon,Lee, Seulchan,Hong, Soon Hyeok
supporting information, p. 5501 - 5505 (2021/07/26)
A highly efficient, direct C(sp3)-H cyanation was developed under mild photocatalytic conditions. The method enabled the direct cyanation of various C(sp3)-H substrates with excellent functional group tolerance. Notably, complex natural products and bioactive compounds were efficiently cyanated.
A 2 - hydroxy dissidents calcium synthetic method
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Paragraph 0020-0022; 0030-0032; 0039-0041, (2019/07/05)
The invention discloses a 2 - hydroxy dissidents calcium synthetic method: to different pentanals, sodium bisulfite, sodium cyanide as raw material through nucleophilic addition reaction in the synthesis of 2 - hydroxy different fifth heavenly stem nitrile, then in acidic conditions by the hydrolysis reaction of the 2 - hydroxy dissidents acid, the final calcium salt exchange reaction 2 - hydroxy dissidents calcium, then refined to get the pure product 2 - hydroxy dissidents acid calcium, refined pure product purity as high as 99.7%, three-step [...] yield is up to 80% or more. The method has the production cycle is short, simple and convenient operation, is suitable for industrial production.
Unsymmetric salen ligands bearing a Lewis base: Intramolecularly cooperative catalysis for cyanosilylation of aldehydes
Wen, Ye-Qian,Ren, Wei-Min,Lu, Xiao-Bing
supporting information; experimental part, p. 6323 - 6330 (2011/10/09)
A series of unsymmetric salen ligands derived from 1,2-diaminocyclohexane bearing an appended Lewis base on the three-position of one aromatic ring were synthesized by the reaction of various functional salicyaldehydes with the condensation product of 1,2-diaminocyclohexane mono(hydrogen chloride) and 3,5-di-tert-butylsalicylaldehyde. These ligands in conjunction with Ti(O iPr)4 exhibited excellent activity in catalyzing the cyanosilylation of aldehydes with trimethylsilyl cyanide (TMSCN) at mild conditions. The highest activity was observed in the catalyst system with regard to the salen ligand bearing a diethylamino group, which proved to be active even at a high [aldehyde]/[catalyst] ratio up to 50000. In a low catalyst loading of 0.05 mol%, the quantitative conversion of benzaldehyde to the corresponding cyanosilylation product was found within 10 min. at ambient temperature. An intramolecularly cooperative catalysis was proposed wherein the central metal Ti(iv) is suggested to play a role of Lewis acid to activate aldehydes while the appended Lewis base to activate TMSCN.