1609373-98-9

Usage

Uses

Used in Organic Synthesis:
2-Methylbenzofuro[2,3-b]pyridin-8-yl trifluoromethanesulfonate is used as a reagent for the introduction of the 8-triflate group onto different substrates in organic synthesis. Its trifluoromethanesulfonate salt nature makes it an effective leaving group, thereby enhancing the reactivity of the compound in various chemical reactions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Methylbenzofuro[2,3-b]pyridin-8-yl trifluoromethanesulfonate is utilized as a key intermediate in the synthesis of complex organic molecules, including potential drug candidates. Its specific structure and properties contribute to the development of novel therapeutic agents with unique pharmacological profiles.
Used in Chemical Research:
2-Methylbenzofuro[2,3-b]pyridin-8-yl trifluoromethanesulfonate is also employed in chemical research as a model compound to study the reactivity and properties of trifluoromethanesulfonate salts. This helps in understanding the underlying mechanisms of reactions involving such leaving groups and contributes to the advancement of organic chemistry.

Upstream product

• 42753-71-9 5-bromo-6-methyl-pyridin-2-ylamine 
• 958357-86-3 2-amino-5-bromo-3-iodo-6-methylpyridine 
• 952948-94-6 3-bromo-5-chloro-6-methylpyridin-2-amine 
• 1824-81-3 2-Amino-6-methylpyridine 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 1609373-97-8 2-methylbenzofuro[2,3-b]pyridine-8-ol 
• 1609373-96-7 8-methoxy-2-methylbenzofuro[2,3-b]pyridine 
• 1609373-95-6 3-(2,3-dimethoxyphenyl)-6-methylpyridin-2-amine 
• 126325-46-0 2-amino-3-bromo-6-methyl-pyridine 
• 40972-86-9 (2,3-dimethoxyphenyl)boronic acid 

Downstream Products

• 1609373-99-0 1,2-methyl-8-(2-pyridine)benzofuran[2,3-B]pyridine 
• 1609374-04-0 2-methyl-8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzofuro[2,3-b]pyridine 

Relevant academic research and scientific papers

Synthesis, characterization, and photoelectric properties of iridium(iii) complexes containing an N hetero-dibenzofuran C^N ligand

In this study, three high-efficient green light iridium(iii) complexes were designed and synthesized, wherein 2-methyl-8-(2-pyridine) benzofuran [2,3-B] pyridine (MPBFP) is the main ligand and three β-diketone derivatives, namely 3,7-diethyl-4,6-nondiazone (detd), 2,2,6,6-tetramethyl-3,5-heptyldione (tmd) and acetylacetone (acac), are ancillary ligands. The thermal stabilities, electrochemical properties, and electroluminescence (EL) performance of these three complexes, namely (MPBFP)2Ir(detd), (MPBFP)2Ir(tmd) and (MPBFP)2Ir(acac), were investigated. The results show that the absorption peaks of the three complexes range from 260 to 340 nm, and the maximum emission wavelengths are 537 nm, 544 nm and 540 nm, respectively. The LUMO level is ?2.18 eV, ?2.20 eV, ?2.21 eV, and the HOMO level is ?5.30 eV, ?5.25 eV, and ?5.25 eV, respectively. The thermal decomposition temperatures of each of the three compounds are 359 °C, 389 °C and 410 °C respectively, with a weight loss of 5%. Green phosphorescent electroluminescent devices were prepared with the structure of ITO/HAT-CN/TAPC/TCTA/TCTA:X/Bepp2/LiF/Al, and the three complexes were dispersed in the organic light-emitting layer as the guest material X. The maximum external quantum efficiency of the devices is 17.2%, 16.7%, and 16.5%, respectively. The maximum brightness is 57?328 cd m?2, 69?267 cd m?2and 69?267 cd m?2, respectively. With respect to the EL properties, (MPBFP)2Ir(detd) is the best performer among the three complexes. The different performances exhibited by these complexes were discussed from the view point of substituent effect on the β-diketone ligands.

Synthesis method of nitrogen-containing deuterated methyl compound

The invention discloses a synthesis method of a nitrogen-containing deuterated methyl compound. The method comprises the following steps: 2-amino-6-methylpyridine used as an initial raw material reacts with an aprotic solution of N-bromosuccinimide, separation is performed to obtain a compound 1, the compound 1 is subjected to an iodination reaction, palladium catalysis, cyclization, hydroxyl trifluoromethanesulfonic acid anhydridization and a deuteration reaction, and then extraction, organic phase mixing, saturated salt water washing, drying, spin-drying, column separation and other post-treatments to obtain the final product. The raw material has a low cost and is easy to obtain, so compared with other synthesis routes, the synthesis method of the nitrogen-containing deuterated methyl compound has the advantages of obvious reduction of the cost, good separation effect, few impurities, suitableness for large-scale production, and increase of the demethylation synthesis yield; the deuterated product can be effectively obtained through method, the deuteration rate can reach 97%, the production temperature is not higher than 100 DEG C to easily achieve safe production, and the practical value is high.

Iridium complexes with aza-benzo fused ligands

Novel iridium complexes containing phenylpyridine and pyridyl aza-benzo fused ligands are described. These complexes are useful as light emitters when incorporated into OLEDs.