16437-69-7 Usage
Description
Acetic acid methylthiomethyl ester, also known as methylthiomethyl acetate, is a chemical compound characterized by its clear, colorless liquid form and a pungent odor. It is widely recognized for its role in the production of flavors and fragrances, and also serves as a versatile solvent in various industrial applications. Additionally, it is a key intermediate in the synthesis of pharmaceuticals and other organic compounds, establishing its significance as a fundamental building block in chemical manufacturing. Due to its potential to cause irritation to the skin, eyes, and respiratory system, it is crucial to handle acetic acid methylthiomethyl ester with appropriate care.
Uses
Used in Flavor and Fragrance Industry:
Acetic acid methylthiomethyl ester is used as a key ingredient in the creation of various flavors and fragrances, leveraging its distinctive pungent odor to enhance the sensory profiles of products in this industry.
Used in Solvent Applications:
In various industrial applications, acetic acid methylthiomethyl ester is utilized as a solvent, capitalizing on its ability to dissolve a wide range of substances, which is essential for processes such as chemical synthesis and material production.
Used in Pharmaceutical Synthesis:
As a crucial intermediate in the synthesis of pharmaceuticals, acetic acid methylthiomethyl ester is used in the development and manufacturing of various medicinal compounds, contributing to the advancement of healthcare and medicine.
Used in Chemical Manufacturing:
Recognized for its importance as a building block in chemical manufacturing, acetic acid methylthiomethyl ester is employed in the production of a multitude of organic compounds, underpinning the creation of a broad spectrum of chemical products.
Check Digit Verification of cas no
The CAS Registry Mumber 16437-69-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,4,3 and 7 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 16437-69:
(7*1)+(6*6)+(5*4)+(4*3)+(3*7)+(2*6)+(1*9)=117
117 % 10 = 7
So 16437-69-7 is a valid CAS Registry Number.
InChI:InChI=1/C4H8O2S/c1-4(5)6-3-7-2/h3H2,1-2H3
16437-69-7Relevant articles and documents
Convenient Preparation of Methylthiomethyl p-Tolyl Sulfone Starting from Dimethyl Sulfoxide
Ogura, Katsuyuki,Yahata, Nobuhiro,Watanabe, Jun-ichi,Takahashi, Kazumasa,Iida, Hirotada
, p. 3543 - 3544 (1983)
An efficient method for preparing methylthiomethyl p-tolyl sulfone was accomplished by the Pummerer reaction of dimethyl sulfoxide with acetic anhydride followed by treatment of the resulting acetoxymethyl methyl sulfide with sodium p-toluenesulfinate in the presence of sodium acetate in acetic acid.
Direct introduction of CH2SMe group in aromatic ring
Zaraiskii,Kachurin
, p. 1572 - 1575 (2003)
Application as a reagent of an accessible methylthiomethyl acetate in a reaction carried out under two-phase conditions and electrophilic catalysis can become a promising procedure for preparation of methylthiomethyl-substituted arenes.
Oae et al.
, p. 817 (1963)
Assessment of heat-sensitive thiophosphate protecting groups in the development of thermolytic DNA oligonucleotide prodrugs
Ausín, Cristina,Kauffman, Jon S.,Duff, Robert J.,Shivaprasad, Shankaramma,Beaucage, Serge L.
experimental part, p. 68 - 79 (2010/03/04)
Heat-sensitive thiophosphate protecting groups derived from the alcohol 4 or 10 have provided insights in the design of DNA oligonucleotide prodrugs. Indeed, functional groups stemming from the alcohol 9, 15, 16 or 22 may be applicable to thiophosphate protection of immunostimulatory CpG DNA motifs, whereas those originating from the alcohol 3, 5, 12, 13, 18, 20 or 22 offer adequate protection of terminal phosphodiester functions against ubiquitous exonucleases that may be found in biological environments. Functional groups derived from the alcohol 9, 15, 16, 19 or 23 are suitable for the protection of phosphodiester functions flanking the CpG motifs of immunomodulatory DNA sequences.
