16906-73-3

Upstream product

• 6293-71-6 4,4'-dimethoxydiphenyliodonium iodide 
• 128-04-1 sodium dimethyldithiocarbamate 
• 100-66-3 methoxybenzene 
• 696-62-8 para-iodoanisole 
• 75-15-0 carbon disulfide 
• 104-94-9 4-methoxy-aniline 
• 124-40-3 dimethyl amine 
• 137-26-8 Thiram 
• 97-74-5 bis(dimethylthiocarbamoyl)sulfide 
• 5720-07-0 4-methoxyphenylboronic acid 
• 459-64-3 4-methoxybenzenediazonium tetrafluoroborate 

Downstream Products

• 3393-77-9 bis(4-methoxyphenyl)sulfide 
• 38695-13-5 1-fluoro-4-[(4-methoxyphenyl)thio]benzene 

Relevant academic research and scientific papers

Synthesis of Aryl Dithiocarbamates from Tetramethylthiuram Monosulfide (TMTM) and Aryl Boronic Acids: Copper-Catalyzed Construction of C(sp2)-S Bonds

A highly efficient method for the synthesis of S-aryl dithiocarbamates is reported. By using tetramethylthiuram monosulfide (TMTM) and aryl boronic acids as starting materials, C(sp2)-S bondforming reactions proceed smoothly to give the desired aryl dithiocarbamates in good to excellent yields. The methodology features a simple procedure, broad functional group tolerance and excellent yields, whilst showing potential synthetic value for the preparation of a diverse range of biologically and pharmaceutically active compounds.

An Efficient Copper-Catalyzed C(sp 2)-S Formation Starting from Aryl Iodides and Tetramethylthiuram Monosulfide (TMTM)

A new, efficient copper-catalyzed C(sp 2)-S formation of phenyl dithiocarbamates starting from aryl iodides and tetramethylthiuram monosulfide (TMTM) was developed. The target compounds, phenyl dithiocarbamates with active sites, were synthesized smoothly in good to excellent yields. The easy performance, high yields, decent functional group compatibility, and cost-effective substrates make the protocol practical and attractive in C-S bond formation.

Aryldithiocarbamates as thiol alternatives in Cu-catalyzed C(aryl)-S coupling reactions using aryldiazonium tetrafluoroborate salts

An efficient method for the synthesis of unsymmetrical diaryl sulfides has been developed by the C-S cross coupling of aryldithiocarbamates and aryldiazonium salts in the presence of CuI-2,2′-bipyridine and Zn. Aryldithiocarbamate compounds have been used here as thiol substitutes. The protocol shows wide substrate scope and good yields of the products.

Copper-Catalyzed Synthesis of S-Aryl Dithiocarbamates from Tetraalkylthiuram Disulfides and Aryl Iodides in Water

An efficient approach for the copper-catalyzed synthesis of aryl dithiocarbamates from aryl iodides and tetraalkylthiuram disulfides in water is described. Without additional ligand and organic solvent, the coupling reaction could provide a series of S-aryl dithiocarbamates in moderate to good yields.

Synthesis of Phenyl Dithiocarbamates Starting from Sodium Dialkyldithiocarbamates and Aryl Boronic Acids: a Copper Catalyzed S-Arylation

A convenient and efficient protocol for the S-arylation of sodium dialkyldithiocarbamates was developed. With the catalysis of copper(I) bromide, sodium dialkyldithiocarbamates coupled with aryl boronic acids giving the C-S coupling products smoothly in g

A Highly Efficient CuCl 2 -Catalyzed C-S Coupling of Aryl Iodides with Tetraalkylthiuram Disulfides: Synthesis of Aryl Dithiocarbamates

A highly efficient copper(II)-catalyzed C-S cross-coupling reaction of aryl iodides with tetraalkylthiuram disulfides was developed. With only 1 mol% of CuCl 2 as catalyst, zinc powder as reductant, and K 2 CO 3 as base, aryl iodides reacted with tetraalkylthiuram disulfides in DMSO furnishing the corresponding aryl dithiocarbamates in good to excellent yields. This protocol is an improvement of previous work, it features convenient performance, low addition of catalyst, no requirement for any ligand, and provides good yields. The method has a broad substrate scope and uses cheap and readily available starting materials.

Copper-Catalyzed C(sp2)-S Coupling Reactions for the Synthesis of Aryl Dithiocarbamates with Thiuram Disulfide Reagents

An efficient protocol for the copper-catalyzed preparation of aryl dithiocarbamates from aryl iodides and inexpensive, environmentally benign tetraalkylthiuram disulfides was developed. The features of mild reaction conditions, high yields, and broad substrate scope render this new approach synthetically attractive for the preparation of potentially biologically active compounds.

Transition-Metal-Free C-S Bond Formation: Aqueous Synthesis of S-Aryl Dithiocarbamates by the use of Stable Arenediazonium Salts Mediated by Nano-Magnetic Supported Silica Sulfonic Acid

A convenient and transition-metal-free method for the synthesis of S-aryl dithiocarbamates based on the reaction of stable arenediazonium nano-magneto silica sulfates (ArN2+-OSO3-SiO2@Fe3O4) with dithiocarbamic acid at room temperature was studied. Avoiding the use of any hazardous transition metal, simple procedure, low cast, and short reaction time are noteworthy advantages of this methodology.

A new method for the synthesis of dithiocarbamates by CuI-catalyzed coupling reaction

The Ullmann-type coupling reaction of sodium dithiocarbamates with aryl iodides and vinyl bromides catalyzed by CuI/N,N-dimethylglycine proceeds smoothly in DMF at 110 °C to give corresponding dithiocarbamates in good yields.