17012-93-0Relevant academic research and scientific papers
Silicon-Promoted Carbon-Carbon Bond Formation between Ketones and Allyl- or Vinylsilanes Catalyzed by Manganese(IV) Dioxide
Hwu, Jih Ru,Chen, Buh-Luen,Shiao, Shui-Sheng
, p. 2448 - 2455 (2007/10/02)
The influence of silicon on the carbon-carbon bond formation was investigated by use of various silylalkenes to react with ketones.Treatment of an allylsilane (CH2=CHCH2SiMemPhn; m + n = 3) with various ketones (20 equiv) in the presence of MnO2 (2.0 equi
ADDITION OF TRIMETHYLSILYLMETHYLMAGNESIUM CHLORIDE TO α,β-UNSATURATED CARBONYLS
Taylor, Richard T.,Galloway, James G.
, p. 295 - 300 (2007/10/02)
Reactions of α,β-unsaturated carbonyl compounds with Me3SiCH2MgCl, prepared from chloromethyltrimethylsilane , were examined.Unlike its lithium counterpart (Me3SiCH2Li), which adds to α,β-unsaturated ketones in the 1,2-sense, the Grignard reagent afforts γ silanes via a 1,4-addition sequence.This tendency is accenturated by the addition of Cu2Br2.Addition of the Grignard reagent to α,β-unsaturated aldehydes gives the simple 1,2-addition products.
