17012-93-0Relevant articles and documents
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Sonnek,G. et al.
, p. 23 - 30 (1977)
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ADDITION OF TRIMETHYLSILYLMETHYLMAGNESIUM CHLORIDE TO α,β-UNSATURATED CARBONYLS
Taylor, Richard T.,Galloway, James G.
, p. 295 - 300 (2007/10/02)
Reactions of α,β-unsaturated carbonyl compounds with Me3SiCH2MgCl, prepared from chloromethyltrimethylsilane , were examined.Unlike its lithium counterpart (Me3SiCH2Li), which adds to α,β-unsaturated ketones in the 1,2-sense, the Grignard reagent afforts γ silanes via a 1,4-addition sequence.This tendency is accenturated by the addition of Cu2Br2.Addition of the Grignard reagent to α,β-unsaturated aldehydes gives the simple 1,2-addition products.
