17119-69-6Relevant articles and documents
Photochemical Strategy for Carbon Isotope Exchange with CO2
Babin, Victor,Talbot, Alex,Labiche, Alexandre,Destro, Gianluca,Del Vecchio, Antonio,Elmore, Charles S.,Taran, Frédéric,Sallustrau, Antoine,Audisio, Davide
, p. 2968 - 2976 (2021/03/09)
A photocatalytic approach for carbon isotope exchange is reported. Utilizing [13C]CO2 and [14C]CO2 as primary C1 sources, this protocol allows the insertion of the desired carbon isotope into phenyl acetic acids without the need for structural modifications or prefunctionalization in one single step. The exceptionally mild conditions required for this traceless transformation are in stark contrast with those for previous methods requiring the use of harsh thermal conditions.
N-benzylation/benzylic C-H amidation cascade by the (ζ3- Benzyl)palladium system in aqueous media: An effective pathway for the direct construction of 3-phenyl-3,4-dihydro-(2H)-1,2,4-benzothiadiazine 1,1-dioxides
Hikawa, Hidemasa,Matsuda, Naoya,Suzuki, Hideharu,Yokoyama, Yuusaku,Azumaya, Isao
supporting information, p. 2308 - 2320 (2013/10/01)
We demonstrate a unique strategy for a benzylation/benzylic C-H amidation cascade reaction by the (ζ3-benzyl)palladium system derived from a palladium catalyst and benzyl alcohol. This tandem process is devised as a new synthetic route for 3-phenyl-3,4-dihydro-(2H)-1,2,4-benzothiadiazine-1,1- dioxide. Water plays an important role for the smooth generation of the (ζ3-benzyl)palladium species, and a bis-benzylated Pd(II) intermediate would be formed in our catalytic system. Atom economical processes such as benzylic C-H activation, cascade reactions and chemoselective reactions in aqueous media have been developed.
Reaction of 1,2-Diphenylethane with D2
Guthrie, Robert D.,Shi, Buchang,Rajagopal, Venkatsubramanian,Ramakrishnan, Sreekumar,Davis, Burtron H.
, p. 7426 - 7432 (2007/10/02)
The reaction of 1,2-diphenylethane (DPE) with D2 (2000 psi) was studied at 450 deg C.The results of GC/MS and NMR analysis of reaction products and of products from reactions of 1,2-diphenylethane-1,1-d2, 1,2-di(phenyl-d5)ethane, and 1,2,3,4-tetraphenylbutane confirm a mechanistic scheme in which the main process for introduction of D is the reaction of 1,2-diphenylethyl radical with D2.This reaction, though energetically uphill, competes with termination processes because of the high concentration of D2 relative to that of radical species.The reaction generates D atoms which attack aromatic ring positions to give substitution for both H and alkyl substituents.Evidence is provided for D and H atom transfer between aliphatic positions in DPE in the presence of either N2 or H2 and between aromatic positions only when provoked by H2 or D2.Only a small amount of exchange between aromatic and aliphatic positions is observed under any conditions.The attack of D atoms at H-carrying aromatic positions makes H atoms available for transfer to other aromatic positions.The process results in a D2-provoked generation of benzene-d0.Mechanistic alternatives for these and other processes are discussed.