17119-69-6

Upstream product

• 98-07-7 Benzotrichlorid 
• 1124-18-1 toluene-d3 
• 151390-61-3 1,2-Di(phenyl-d5)ethane 
• 93-58-3 benzoic acid methyl ester 
• 1076-07-9 2,2-dideuterio-2-phenyl-acetic acid 
• 1111-72-4 carbon dioxide 
• 100-42-5 styrene 
• 100-51-6 benzyl alcohol 
• 100-52-7 benzaldehyde 
• 21175-64-4 1,1-dideuteriophenylmethanol 
• 28144-70-9 anthranilic acid amide 
• 121998-76-3 2-phenyl-2,3-dihydro-4(1H)-quinazolinone 
• 7789-20-0 water-d2 
• 3481-15-0 benzyl alcohol-d1 

Downstream Products

• 76885-73-9 C₃₀H₃₀⁽²⁾H₆O₁₀S₂ 
• 51271-29-5 [1',1'-2H₂]benzyl bromide 
• 66343-88-2 racemic benzyl-α-d₁ bromide 
• 33712-34-4 benzyl-d2 chloride 
• 79449-94-8 (chloromethyl-d)benzene 

Relevant academic research and scientific papers

Photochemical Strategy for Carbon Isotope Exchange with CO2

A photocatalytic approach for carbon isotope exchange is reported. Utilizing [13C]CO2 and [14C]CO2 as primary C1 sources, this protocol allows the insertion of the desired carbon isotope into phenyl acetic acids without the need for structural modifications or prefunctionalization in one single step. The exceptionally mild conditions required for this traceless transformation are in stark contrast with those for previous methods requiring the use of harsh thermal conditions.

Dramatic Synergy in CoPt Nanocatalysts Stabilized by "click" Dendrimers for Evolution of Hydrogen from Hydrolysis of Ammonia Borane

Hydrolysis of ammonia borane (AB) is a very convenient source of H2, but this reaction needs catalytic activation to become practical under ambient conditions. Here this reaction is catalyzed by bimetallic late transition-metal nanoparticles (N

N-benzylation/benzylic C-H amidation cascade by the (ζ3- Benzyl)palladium system in aqueous media: An effective pathway for the direct construction of 3-phenyl-3,4-dihydro-(2H)-1,2,4-benzothiadiazine 1,1-dioxides

We demonstrate a unique strategy for a benzylation/benzylic C-H amidation cascade reaction by the (ζ3-benzyl)palladium system derived from a palladium catalyst and benzyl alcohol. This tandem process is devised as a new synthetic route for 3-phenyl-3,4-dihydro-(2H)-1,2,4-benzothiadiazine-1,1- dioxide. Water plays an important role for the smooth generation of the (ζ3-benzyl)palladium species, and a bis-benzylated Pd(II) intermediate would be formed in our catalytic system. Atom economical processes such as benzylic C-H activation, cascade reactions and chemoselective reactions in aqueous media have been developed.

Pd-catalyzed benzylic C-H amidation with benzyl alcohols in water: A strategy to construct quinazolinones

A novel method for the synthesis of 4-phenylquinazolinones via a palladium-catalyzed domino reaction of o-aminobenzamides with benzyl alcohols is developed. This protocol involves N-benzylation, benzylic C-H amidation, and dehydrogenation in water, which may play an important role in the smooth generation of the (η3-benzyl)palladium species by activation of the hydroxyl group of the benzyl alcohol.

Reaction of 1,2-Diphenylethane with D2

The reaction of 1,2-diphenylethane (DPE) with D2 (2000 psi) was studied at 450 deg C.The results of GC/MS and NMR analysis of reaction products and of products from reactions of 1,2-diphenylethane-1,1-d2, 1,2-di(phenyl-d5)ethane, and 1,2,3,4-tetraphenylbutane confirm a mechanistic scheme in which the main process for introduction of D is the reaction of 1,2-diphenylethyl radical with D2.This reaction, though energetically uphill, competes with termination processes because of the high concentration of D2 relative to that of radical species.The reaction generates D atoms which attack aromatic ring positions to give substitution for both H and alkyl substituents.Evidence is provided for D and H atom transfer between aliphatic positions in DPE in the presence of either N2 or H2 and between aromatic positions only when provoked by H2 or D2.Only a small amount of exchange between aromatic and aliphatic positions is observed under any conditions.The attack of D atoms at H-carrying aromatic positions makes H atoms available for transfer to other aromatic positions.The process results in a D2-provoked generation of benzene-d0.Mechanistic alternatives for these and other processes are discussed.

Primary and Secondary Kinetic Isotope Effects in the Decomposition of a Tertiary Alkoxide

Kinetic isotope effects have been determined for the elimination of toluene from the alkoxide of 1,2,3-triphenylpropan-2-ol (1a).In DMSO, the rate measurements on 1a and 1,2,3-triphenylpropanol (1b) at 30 deg C give kH4/kC4/

Primary and Secondary Kinetic Hydrogen Isotope Effects in the Solution and Gas Phase Decomposition of t-Alkoxides

Primary and secondary kinetic hydrogen isotope effects (k.i.e.s) in the elimination of toluene from the alkoxide of 1,2,3-triphenylpropane-2-ol have been determined and are consistent with rate limiting proton transfer in gas phase reaction and with rate limiting carbon-carbon bond cleavage in reaction in dimethyl sulphoxide (DMSO) solution.

Side Chain Hydroxylation of Aromatic Hydrocarbons by Fungi. Part 2. Isotope Effects and Mechanism

The benzylic hydroxylation of ethylbenzene, p-diethylbenzene, tetralin, indane, and toluene by the fungi Mortierella isabellina, Cunninghamella echinulata, and Helminthosporium species has been investigated by the use of deuterium-labelled substrates.An i

Primary and Secondary Kinetic Deuterium Isotope Effects and Transition-State Structures for Benzylic Chlorination and Bromination of Toluene

As a chemical model for benzylic hydroxylations effected by cytochrome P-450 enzymes, the chlorination of PhCH3, PhCH2D, PhCHD2, and PhCD3 in a two-phase system of hypochlorite/CH2Cl2 with a phase-transfer catalyst has been investigated.On the basis of th