1833-48-3

Basic information

• Product Name: Ethanone, 1-[4-[(trimethylsilyl)methyl]phenyl]-
• CAS NO: 1833-48-3
• Molecular Formula: C12H18OSi
• Molecular Weight: 206.36
• Mol File: 1833-48-3.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[4-[(trimethylsilyl)methyl]phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[4-[(trimethylsilyl)methyl]phenyl]-(1833-48-3)
• EPA Substance Registry System: Ethanone, 1-[4-[(trimethylsilyl)methyl]phenyl]-(1833-48-3)

Safety Data

• Hazardous Substances Data: 1833-48-3(Hazardous Substances Data)

Upstream product

• 99-90-1 para-bromoacetophenone 
• 69833-15-4 tris{(trimethylsilyl)methyl}indium 
• 225931-80-6 bis[(trimethylsilyl)methyl](1,5-cyclooctadiene)palladium(II) 
• 213182-83-3 N-[2-(diphenylphosphino)-1-phenylethylidene]-2,6-diisopropyl-aniline 
• 109613-00-5 4-acetophenyl triflate 
• 7550-35-8 lithium bromide 
• 13329-40-3 4-Iodoacetophenone 
• 1822-00-0 trimethylsilylmethyllithium 
• 74213-41-5 ((trimethylsilyl)methyl)boronic acid 
• 76374-84-0 tetramethylammonium tetrakis(trimethylsilylmethyl)borate 
• 770-09-2 benzyltrimethylsilane 
• 75-36-5 acetyl chloride 

Downstream Products

• 52000-49-4 3-Oxo-3-(4-trimethylsilanylmethyl-phenyl)-propionic acid ethyl ester 
• 16571-41-8 trimethylsilyl radical 
• 41876-38-4 4-acetylbenzyl radical 

Relevant articles and documents

Scalable Negishi Coupling between Organozinc Compounds and (Hetero)Aryl Bromides under Aerobic Conditions when using Bulk Water or Deep Eutectic Solvents with no Additional Ligands

Pd-catalyzed Negishi cross-coupling reactions between organozinc compounds and (hetero)aryl bromides have been reported when using bulk water as the reaction medium in the presence of NaCl or the biodegradable choline chloride/urea eutectic mixture. Both C(sp3)-C(sp2) and C(sp2)-C(sp2) couplings have been found to proceed smoothly, with high chemoselectivity, under mild conditions (room temperature or 60 °C) in air, and in competition with protonolysis. Additional benefits include very short reaction times (20 s), good to excellent yields (up to 98 %), wide substrate scope, and the tolerance of a variety of functional groups. The proposed novel protocol is scalable, and the practicability of the method is further highlighted by an easy recycling of both the catalyst and the eutectic mixture or water.

B-alkyl suzuki-miyaura cross-coupling reactions with air-stable potassium alkyltrifluoroborates

The palladium-catalyzed cross-coupling reaction of substituted potassium alkyltrifluoroborates with aryl halides and aryl triflates proceeds readily with moderate to good yields. The potassium alkyltrifluoroborates 1, 2, and 3a-e were easily synthesized and obtained as air-stable crystalline solids that can be stored for long periods of time. All of the cross-couplings proceed under the same reaction conditions using PdCl2(dppf)·CH2cl2 as catalyst in THF-H2O in the presence of 3 equiv of Cs2CO3 as base.

Atom-efficient metal-catalyzed cross-coupling reaction of indium organometallics with organic electrophiles

The novel metal-catalyzed cross-coupling reaction of indium organometallics with organic electrophiles is described. Triorganoindium compounds (R3In) containing alkyl, vinyl, aryl, and alkynyl groups are efficiently prepared from the correspond