18476-67-0Relevant articles and documents
Method for synthesizing substituted furan
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Paragraph 0010, (2017/12/09)
Provided is a method for synthesizing substituted furan. Iodohydrocarbon and terminal propargyl alcohol produce Sonogashira coupling reaction to generate an intermediate product 3-alkyne-1-alcohol, then isomeric cyclization occurs under the effect of Dess
Gold-catalyzed cycloisomerization of alk-4-yn-1-ones
Belting, Volker,Krause, Norbert
supporting information; experimental part, p. 1221 - 1225 (2009/05/30)
Depending on the substitution pattern and the solvent, the gold-catalyzed cyclization of alk-4-yn-1-ones 1 affords different oxygen heterocycles under mild reaction conditions. Alkynones with one substituent at C-3 undergo a 5-exo-dig cycloisomerization t
2,5-Disubstituted furans from 1,4-alkynediols
Pridmore, Simon J.,Slatford, Paul A.,Williams, Jonathan M.J.
, p. 5111 - 5114 (2008/02/09)
1,4-Alkynediols serve as readily available starting materials for isomerisation to 1,4-diketones, which can be converted in situ into the corresponding furans by acid-catalysed dehydration. A range of 2,5-disubstituted furans was prepared using the ruthenium-based catalyst Ru(PPh3)3(CO)H2 with Xantphos at 1 mol % loading.
