185244-08-0Relevant articles and documents
Functionalized amido ketones: New anticonvulsant agents
Beguin, Cecile,Andurkar, Shridhar V.,Jin, Albert Y.,Stables, James P.,Weaver, Donald F.,Kohn, Harold
, p. 4275 - 4285 (2007/10/03)
We have reported that functionalized amino acids (FAA) are potent anticonvulsants. Replacing the N-terminal amide group in FAA with phenethyl, styryl, and phenylethynyl units provided a series of functionalized amido ketones (FAK). We show that select FAK
An efficient method for the synthesis of substituted TosMIC precursors
Sisko, Joseph,Mellinger, Mark,Sheldrake, Peter W.,Baine, Neil H.
, p. 8113 - 8116 (2007/10/03)
Substituted tosylmethyl isocyanides (TosMICs) are useful reagents for which no general method of preparation is available. We describe here a high-yielding method for the synthesis of substituted tosylmethyl formamides, which are readily converted to the corresponding isocyanides.