18699-77-9

Basic information

• Product Name: 1,3-Dioxolane, 2,2-dimethyl-4,5-diphenyl-, cis-
• CAS NO: 18699-77-9
• Molecular Formula: C17H18O2
• Molecular Weight: 254.329
• Mol File: 18699-77-9.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 1,3-Dioxolane, 2,2-dimethyl-4,5-diphenyl-, cis-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxolane, 2,2-dimethyl-4,5-diphenyl-, cis-(18699-77-9)
• EPA Substance Registry System: 1,3-Dioxolane, 2,2-dimethyl-4,5-diphenyl-, cis-(18699-77-9)

Safety Data

• Hazardous Substances Data: 18699-77-9(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Odor

Faint floral

Uses

a. Solvent in industrial processes
b. Synthesis of pharmaceuticals
c. Synthesis of agricultural chemicals
d. Synthesis of other organic compounds
e. Manufacture of adhesives
f. Manufacture of plastics
g. Manufacture of coatings

Isomer

cis

Importance

Important in the synthesis of various compounds

Safety precautions

a. Can be irritating to skin and eyes
b. Potential harmful effects if inhaled or ingested
c. Proper handling procedures should be followed
d. Use personal protective equipment (PPE) when handling

Upstream product

• 67-64-1 acetone 
• 7647-01-0 hydrogenchloride 
• 492-70-6 1,2-diphenyl-1,2-ethanediol 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 77-76-9 2,2-dimethoxy-propane 
• 1439-07-2 (R,R)-trans-stilbene epoxide 
• 1439-07-2 trans-Stilbene oxide 
• 103-30-0 (E)-1,2-diphenyl-ethene 
• 645-49-8 cis-stilben 

Downstream Products

• 655-48-1 DL-1,2-diphenylethane-1,2-diol 
• 5876-78-8 trans-diphenyl-4,5 dimethyl-2,2 dioxolanne-1,3 
• 5928-67-6 (S)-(+)-benzoin 
• 5928-66-5 (R)-benzoin 
• 100-52-7 benzaldehyde 
• 65-85-0 benzoic acid 

Relevant articles and documents

Ultrasound Assisted the Synthesis of 1,3-Dioxolane Derivatives from the Reaction of Epoxides or 1,2-Diols with Various Ketones Using Graphene Oxide Catalyst

Abstract: The main objective of this study concerns the sonochemical synthesis of 1,3-dioxolane derivatives using graphene oxide catalyst by applying two methods. In the first method, we described the synthesis of 1,3-dioxolane by ring-opening of epoxides in the presence of ketones catalyzed by graphene oxide (GO) under ultrasonic irradiation. In the second sonochemical procedure, we described the synthesis of 1,3-dioxolane derivatives by the reaction of 1,2-diols with ketones using same GO catalyst. Mild reaction conditions, high yields, short reaction times, reusability of catalyst and easy isolation of the products make the developed methods very useful. Graphic Abstract: [Figure not available: see fulltext.]

OXONE-ACETONE MEDIATED METAL FREE PREPARATION OF SYN-DIOLS

The present invention disclose a simple and high yielding process of Oxone-acetone mediated metal free syn-dihydroxylation of benzo fused olefins of formula (II) to obtain library of dioxolo compounds of formula (I). The invention further disclsoe a simple and high yielding process of Oxone-acetone mediated metal free syn-dihydroxylation of stilbene and its derivatives of formula (III) thereof. Also disclosed herein is Wacker-type oxidation of benzo-fused olefins of formula (X). The invention further disclose compounds of formula (I) which can be useful for the treatment of HIV, cancer or malaria.

Mild and efficient protection of diol and carbonyls as cyclic acetals catalysed by iron (III) chloride

A friendly method for the protection of diols and carbonyls catalysed by hexahydrated iron (III) chloride has been developed. This method, which consists of the transformation of diols and carbonyls to cyclic acetals, functions in mild conditions and it is efficient for a wide range of diols.