19005-95-9

Usage

InChI:InChI=1/C9H13NO/c1-5-6(2)10-7(3)9(5)8(4)11/h10H,1-4H3

Upstream product

• 2199-41-9 2,3,5-trimethylpyrrole 
• 676-58-4 methylmagnesium chloride 
• 75-36-5 acetyl chloride 
• 135636-66-7 butane-2,3-dione mono-oxime 
• 123-54-6 acetylacetone 
• 75-15-0 carbon disulfide 
• 7446-70-0 aluminium trichloride 
• 861615-46-5 3-oxo-3-(2,4,5-trimethyl-pyrrol-3-yl)-propionitrile 
• 67-56-1 methanol 
• 64-19-7 acetic acid 
• 2386-25-6 2,4-dimethyl-3-acetylpyrrole 

Downstream Products

• 1003-90-3 2,3,4,5-tetramethylpyrrole 
• 1617532-88-3 5-(2-methyl-4,5-diphenyl-1H-pyrrol-3-yl)-1-phenyl-1H-pyrazole 
• 1617532-89-4 3-(2-methyl-4,5-diphenyl-1H-pyrrol-3-yl)isoxazole 
• 1617532-90-7 7-(2-methyl-4,5-diphenyl-1H-pyrrol-3-yl)pyrazolo[1,5-a] pyrimidine-3-carbonitrile 
• 1617532-92-9 7-(2-methyl-4,5-diphenyl-1H-pyrrol-3-yl)-[1,2,4]triazolo[1,5-a] pyrimidine 
• 1617532-93-0 7-(2-methyl-4,5-diphenyl-1H-pyrrol-3-yl)tetrazolo[1,5-a] pyrimidine 
• 1617532-94-1 4-(2-methyl-4,5-diphenyl-1H-pyrrol-3-yl)benzo [4,5]imidazo[1,2-a] pyrimidine 
• 1617532-95-2 5-(2-methyl-4,5-diphenyl-1H-pyrrol-3-yl)-2-thioxo-2,3-dihydropyrido[2,3-d] pyrimidin-4(1H)-one 
• 1617532-96-3 1-(2-methyl-6-(2-methyl-4,5-diphenyl-1H-pyrrol-3-yl)pyridin-3-yl)ethanone 
• 1617532-97-4 ethyl 2-methyl-6-(2-methyl-4,5-diphenyl-1H-pyrrol-3-yl)nicotinate 
• 1617532-98-5 ethyl 6-(2-methyl-4,5-diphenyl-1H-pyrrol-3-yl)-2-phenylnicotinate 
• 1631184-61-6 6-(2-methyl-4,5-diphenyl-1H-pyrrol-3-yl)-2-oxo-1,2-dihydropyridine-3-carbonitrile 
• 1631184-75-2 ethyl 6-(2-methyl-4,5-diphenyl-1H-pyrrol-3-yl)-2-oxo-1,2-dihydropyridine-3-carboxylate 
• 1617532-85-0 E-1-(2-methyl-4,5-diphenyl-1H-pyrrol-3-yl)-3-morpholinoprop-2-en-1-one 

Relevant academic research and scientific papers

Alkylation process

Substituted pyrrole compounds, such as 3-ethyl-4-methyl-5-carbethoxy pyrrole, 2,4-dimethyl-3-acetyl pyrrole and 2-methyl-5-carboxy pyrrole-4-propionic acid diethyl ester, are alkylated in a single step by reaction with an aldehyde or ketone in the presence of both an acid condensing agent such as hydriodic acid and a compatible reducing agent such as metallic zinc or stannous chloride. Suitable carbonyl reactants include formaldehyde, paraldehyde, isobutyraldehyde, acetone, cyclohexanone and methyl-isobutyl ketone. This application is a continuation application of U.S. application Ser. No. 281,624 filed Aug. 18, 1972, now abandoned, which is a continuation-in-part application of U.S. application Ser. No. 832,001, filed June 10, 1969, now abandoned.