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Diethyl ethylphosphoramidate, also known as Vx, is a highly toxic organophosphorus compound that belongs to the class of chemical warfare agents. It is a colorless, odorless, and tasteless oily liquid, making it difficult to detect. Vx is a potent inhibitor of the enzyme acetylcholinesterase, which plays a crucial role in the nervous system by breaking down the neurotransmitter acetylcholine. When Vx inhibits this enzyme, acetylcholine accumulates, leading to overstimulation of the nervous system and potentially fatal consequences. The chemical can be absorbed through the skin, inhaled, or ingested, and it is considered to be more persistent than other nerve agents like sarin or soman, posing a significant threat in both military and terrorist scenarios.

1946-09-4

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1946-09-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1946-09-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,4 and 6 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1946-09:
(6*1)+(5*9)+(4*4)+(3*6)+(2*0)+(1*9)=94
94 % 10 = 4
So 1946-09-4 is a valid CAS Registry Number.

1946-09-4Relevant articles and documents

One-step transformation of ammonium dialkyl phosphoroselenoates into dialkyl phosphoramidates

Mielniczak, Grazyna,Lopusinski, Andrzej

, p. 121 - 127 (2007/10/03)

Ammonium dialkyl phosphoroselenoates are directly converted into the dialkyl phosphoramidates by iodosobenzene and iodoxybenzene. The inversion of configuration at the phosphorus atom, using model diastereoisomeric ammonium cis- and trans-2-oxo-2-seleno-4-methyl-1,3,2-dioxaphosphinan system, was observed. The mechanistic scheme of this transformation is discussed.

Phosphoramidate-mediated conversion of carbonyl ligands into isocyanide ligands: A new approach to chiral isocyanide ligands

Gibson, Susan E.,Ibrahim, Hasim,Pasquier, Corinne,Peplow, Mark A.,Rushton, Julia M.,Steed, Jonathan W.,Sur, Ojit

, p. 269 - 276 (2007/10/03)

Metal isocyanides have been used and studied by organometallic chemists for many years and, as a result, they have a rich and interesting chemistry. The nature of metal-free isocyanides and the methods of making isocyanide complexes, however, has resulted

Phosphoramidate-mediated conversion of metal carbonyls into metal isonitriles

Gibson, Susan E.,Hinkamp, Thomas W.,Peplow, Mark A.,Ward, Mark F.

, p. 1671 - 1672 (2007/10/03)

The reaction of metal carbonyls with readily-available phosphoramidate anions provides a new route to metal isonitriles; in particular, enantiomerically pure isonitrile complexes are easily accessed by this method.

Fungicides for the control of take-all disease of plants

-

, (2008/06/13)

A method of controlling Take-All disease of plants by applying a fungicide of the formula STR1 wherein Z1 and Z2 are C and are part of an aromatic ring which is benzothiophene; and A is selected from --C(X)-amine wherein the amine is an unsubstituted, monosubstituted or disubstituted amino radical, --C(O)--SR3, --NH--C(X)R4, and --C(=NR3)--XR7 ; B is --Wm --Q(R2)3 or selected from O-tolyl, 1-naphthyl, 2-naphthyl, and 9-phenanthryl, each optionally substituted with halogen or R4 ; Q is C, Si, Ge, or Sn; W is --C(R3)p H(2-p) --; or when Q is C, W is selected from --C(R3)p H(2-p), --N(R3)m H(1-m)--, --S(O)p--, and --O--; X is 0 or S; n is 0, 1, 2, or 3; m is 0 or 1; p is 0, 1, or 2; each R and R2 is independently defined herein; R3 is C1 -C4 alkyl; R4 is C1 -C4 alkyl, haloalkyl, alkoxy, alkylthio, alkylamino, or dialkylamino; and R7 is C1 -C4 alkyl, haloalkyl, or phenyl, optionally substituted with halo, nitro, or R4 ; or an agronomic salt thereof.

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